Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Anastasia Zoga"'
Autor:
Ioannis Kostopoulos, AL Skaltsounis, Ourania E. Tsitsilonis, Antigone Lazou, M Tsoumani, Anastasia Zoga, Andreas Papapetropoulos, Ioanna Papatheodorou, Panagiota-Efstathia Nikolaou, Ioanna Andreadou, Efstathios K. Iliodromitis, Anastasios Georgoulis, T Dermintzoglou, I. Tseti, Panagiotis Efentakis
Publikováno v:
European Heart Journal. 42
Background/Introduction Oleuropein (oleu), the main polyphenolic constituent of olive, has cardioprotective effects against ischemia (I) – reperfusion (R) injury (IRI) when administered chronically. Purpose We aimed to assess the cardioprotection a
Autor:
Efstathios K. Iliodromitis, Alexios-Leandros Skaltsounis, Ioanna Andreadou, Panagiota-Efstathia Nikolaou, Andreas Papapetropoulos, Kerstin Boengler, Vassilios Myrianthopoulos, Anna Tsantili-Kakoulidou, Nicholas Gaboriaud-Kolar, Nikolaos Kostomitsopoulos, Rainer Schulz, Konstantina Vouvogiannopoulou, Pavlos Alexakos, Ioannis Rerras, Panagiotis Efentakis, Anastasia Zoga
Publikováno v:
Cardiovascular Research. 115:1228-1243
Aims Glycogen synthase kinase 3 beta (GSK3β) link with the mitochondrial Permeability Transition Pore (mPTP) in cardioprotection is debated. We investigated the role of GSK3β in ischaemia (I)/reperfusion (R) injury using pharmacological tools. Meth
Autor:
Anastasia Zoga, S.I. Bibli, Nicole Pouli, S. Vasileiou, Maria Anastasiou-Nana, D. Kremastinos, E. Iliodromitis, Panagiotis Efentakis, Ioanna Andreadou
Publikováno v:
European Journal of Pharmacology. 789:431-438
We tested the hypothesis that ranolazine (Ran) is cardioprotective in a model of ischemia /reperfusion and we elucidated the intracellular mechanism. Anesthetized rabbits were subjected to is chemia and reperfusion and were divided into 5 groups: 1)
Autor:
Dimitrios Th. Kremastinos, Dimitrios Farmakis, Panagiotis Efentakis, Anastasia Zoga, Emmanuel Mastromanolis, Efstathios K. Iliodromitis, Nikolaos Papaioannou, Ioanna Andreadou, Sofia-Iris Bibli
Publikováno v:
International Journal of Cardiology. 184:140-151
Background We investigated the effectiveness of perconditioning (Perc) applied at different time points along with the role of RISK, SAFE, STAT5 and eNOS pathways. Methods and results Anesthetized rabbits were subjected to 30-min ischemia/3-hour repe
Autor:
Alexios-Leandros Skaltsounis, Dimitra Benaki, Panagiotis Efentakis, Alkistis-Ioanna Milioni, Anastasia Papachristodoulou, Efstathios K. Iliodromitis, Anastasia Zoga, Ioanna Andreadou, Sofia-Iris Bibli, Emmanuel Mikros
Publikováno v:
Planta Medica. 81:655-663
Ischemic preconditioning, which is mediated by cell signaling molecules, protects the heart from ischemia-reperfusion injury by limiting the infarct size. Oleuropein, the main polyphenolic constituent of olives, reduced the infarct size in normal and
Autor:
Nicole Pouli, Spyridon Toumpas, Evangelos Gikas, Panagiotis Efentakis, Alexios-Leandros Skaltsounis, Milos R. Filipovic, Nikolaos Lougiakis, Anastasia Zoga, Ioanna Andreadou, Panagiotis Marakos, Rudolf Wedmann, Efstathios K. Iliodromitis, Zhongmin Zhou, Andreas Papapetropoulos
Publikováno v:
Journal of medicinal chemistry. 59(5)
This work deals with the design, synthesis, and evaluation of the cardioprotective properties of a number of novel hybrid compounds combining the adenine nucleus with a suitable H2S slow-releasing moiety, coupled via a stable ether bond. The H2S rele
Autor:
Anastasia Zoga, Efstathios K. Iliodromitis, Theano Fotopoulou, S.I. Bibli, Dimitrios Th. Kremastinos, Ioanna Andreadou, Maria Koufaki
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:5948-5956
Novel purine analogues bearing nitrate esters were designed and synthesized in an effort to develop compounds triggering endogenous cardioprotective mechanisms such as ischemic preconditioning (IPC) or postconditioning (PostC). The majority of the co
Autor:
Dimitrios Th. Kremastinos, Ioanna Andreadou, Apostolos Papalois, Eftihios Prokovas, Fragiska Sigala, Efstathios K. Iliodromitis, Dimitrios Farmakis, Katerina Spyridaki, Maria Anastasiou-Nana, Andreas Papapetropoulos, Anastasia Zoga
Publikováno v:
Cardiovascular Research. 94:501-509
Aims The effectiveness of postconditioning (POC) in hypercholesterolaemia is in dispute. We investigated the effects of 3-day lipophilc (simvastatin) or hydrophilic (pravastatin) statin treatment, without or with POC in normocholesterolaemic (Norm) a
Autor:
Vassilios Souridis, Eftihios Prokovas, Anastasia Zoga, Anna Tsantili-Kakoulidou, Efstathios K. Iliodromitis, Emmanuel Mikros, Ioanna Andreadou, Sarantos Kostidis, Nikolaos Dagres, Maria Anastasiou-Nana, Dimitrios Th. Kremastinos
Publikováno v:
Journal of Cardiovascular Pharmacology. 58:609-616
Reactive oxygen and nitrogen species are critical in preconditioning (PC). We sought to determine the effect of N-2-mercaptopropionyl glycine (MPG) on infarct size and on the oxidative status. Rabbits were exposed to 30-minute regional ischemia of th
Autor:
Maria Zervou, Dimitrios Th. Kremastinos, Helen Triantafyllidi, George Kokotos, Efstathios K. Iliodromitis, Panagiotis Zoumpoulakis, Thomas Mavromoustakos, Panagiota Moutevelis-Minakakis, Aggeliki Politi, Anastasia Zoga
Publikováno v:
Journal of the Renin-Angiotensin-Aldosterone System. 11:103-110
Introduction: The aim of this study was to establish an optimized fast and safe protocol for the pharmacological screening of AT1 antagonists. Materials and methods : The pharmaceutical prototype AT1 antagonist losartan, its active metabolite EXP3174