Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Anastasia V. Shindyapina"'
Autor:
Kejun Ying, José P. Castro, Anastasia V. Shindyapina, Alexander Tyshkovskiy, Mahdi Moqri, Ludger J. E. Goeminne, Sofiya Milman, Zhengdong D. Zhang, Nir Barzilai, Vadim N. Gladyshev
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract While previous studies identified common genetic variants associated with longevity in centenarians, the role of the rare loss-of-function (LOF) mutation burden remains largely unexplored. Here, we investigated the burden of rare LOF mutatio
Externí odkaz:
https://doaj.org/article/5caa0089e32b4109a566c31b600051c0
Autor:
Raquel Fernando, Anastasia V. Shindyapina, Mario Ost, Didac Santesmasses, Yan Hu, Alexander Tyshkovskiy, Sun Hee Yim, Jürgen Weiss, Vadim N. Gladyshev, Tilman Grune, José Pedro Castro
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Skeletal muscle aging is characterized by the loss of muscle mass, strength and function, mainly attributed to the atrophy of glycolytic fibers. Underlying mechanisms driving the skeletal muscle functional impairment are yet to be elucidated
Externí odkaz:
https://doaj.org/article/b1e477911453427b854cf104b5383a76
Autor:
Aminat Guseynovna Ibragimova, Yaroslav Mikhailovich Stanishevskiy, Alexey Mikhaylovich Plakkhin, Alexandr Vladimirovich Zubko, Nidal Akhmedovich Darvish, Anton Karenovich Koassary, Anastasia V. Shindyapina
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
IntroductionCalcification of soft tissues is a common age-related pathology that primarily occurs within vascular tissue. The mechanisms underlying pathological calcification in humans and tissue specificity of the process is still poorly understood.
Externí odkaz:
https://doaj.org/article/4b1d1500c8d343bfb38403fb31fde909
Autor:
Kejun Ying, Ranran Zhai, Timothy V. Pyrkov, Anastasia V. Shindyapina, Marco Mariotti, Peter O. Fedichev, Xia Shen, Vadim N. Gladyshev
Publikováno v:
Communications Medicine, Vol 1, Iss 1, Pp 1-15 (2021)
Ying et al. conduct a multi-instrument Mendelian randomization study looking at the link between aging and COVID-19 risk. They observe an association between genetic variation implicated in longevity and decreased risk of COVID-19 infection and hospi
Externí odkaz:
https://doaj.org/article/9432b47b0f474ab28368a68b3468e756
Autor:
Kenneth Walsh, Nalini Raghavachari, Candace Kerr, Alexander G. Bick, Steven R. Cummings, Todd Druley, Cynthia E. Dunbar, Giulio Genovese, Margaret A. Goodell, Siddhartha Jaiswal, Jaroslaw Maciejewski, Pradeep Natarajan, Anastasia V. Shindyapina, Alan R. Shuldiner, Erik B. Van Den Akker, Jan Vijg
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Aging is characterized by increased mortality, functional decline, and exponential increases in the incidence of diseases such as cancer, stroke, cardiovascular disease, neurological disease, respiratory disease, etc. Though the role of aging in thes
Externí odkaz:
https://doaj.org/article/91cc6f1fb0f44f728c443e64a1e07a92
The Antioxidant Cofactor Alpha-Lipoic Acid May Control Endogenous Formaldehyde Metabolism in Mammals
Autor:
Anastasia V. Shindyapina, Tatiana V. Komarova, Ekaterina V. Sheshukova, Natalia M. Ershova, Vadim N. Tashlitsky, Alexander V. Kurkin, Ildar R. Yusupov, Garik V. Mkrtchyan, Murat Y. Shagidulin, Yuri L. Dorokhov
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
The healthy human body contains small amounts of metabolic formaldehyde (FA) that mainly results from methanol oxidation by pectin methylesterase, which is active in a vegetable diet and in the gastrointestinal microbiome. With age, the ability to ma
Externí odkaz:
https://doaj.org/article/273250f2cb5a40c69942aca8b084f5ec
Autor:
Ekaterina V. Sheshukova, Tatiana V. Komarova, Natalia M. Ershova, Anastasia V. Shindyapina, Yuri L. Dorokhov
Publikováno v:
Frontiers in Plant Science, Vol 8 (2017)
Although plants as sessile organisms are affected by a variety of stressors in the field, the stress factors for the above-ground and underground parts of the plant and their gene expression profiles are not the same. Here, we investigated NbKPILP, a
Externí odkaz:
https://doaj.org/article/6b201e81c7ac4651b90b8e58e590cb82
Autor:
Ekaterina V. Sheshukova, Tatiana V. Komarova, Denis V. Pozdyshev, Natalia M. Ershova, Anastasia V. Shindyapina, Vadim N. Tashlitsky, Eugene V. Sheval, Yuri L. Dorokhov
Publikováno v:
Frontiers in Plant Science, Vol 8 (2017)
The mechanical damage that often precedes the penetration of a leaf by a pathogen promotes the activation of pectin methylesterase (PME); the activation of PME leads to the emission of methanol, resulting in a “priming” effect on intact leaves, w
Externí odkaz:
https://doaj.org/article/c33b0356328a40df863c14570d9ddfad
Autor:
Anastasia V Shindyapina, Aleksandr A Zenin, Andrei E Tarkhov, Didac Santesmasses, Peter O Fedichev, Vadim N Gladyshev
Publikováno v:
eLife, Vol 9 (2020)
Heritability of human lifespan is 23–33% as evident from twin studies. Genome-wide association studies explored this question by linking particular alleles to lifespan traits. However, genetic variants identified so far can explain only a small fra
Externí odkaz:
https://doaj.org/article/ff3daf06424e4c80a7ff49263016b9fb
Autor:
Rui Ribeiro, Joana C. Macedo, Madalena Costa, Vladimir Ustiyan, Anastasia V. Shindyapina, Alexander Tyshkovskiy, Rita N. Gomes, José Pedro Castro, Tanya V. Kalin, Francisco Vasques-Nóvoa, Diana S. Nascimento, Sergey E. Dmitriev, Vadim N. Gladyshev, Vladimir V. Kalinichenko, Elsa Logarinho
Publikováno v:
Nature Aging. 2:397-411
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39dee783a460982bc9771f1f14e0104c
https://doi.org/10.1038/s43587-022-00209-9
https://doi.org/10.1038/s43587-022-00209-9