Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Anastasia V. Galochkina"'
Autor:
Anna A. Shtro, Artem M. Klabukov, Anzhelika V. Garshinina, Anastasia V. Galochkina, Yulia V. Nikolaeva, Tatyana M. Khomenko, Danila E. Bobkov, Aleksey A. Lozhkov, Konstantin V. Sivak, Kirill S. Yakovlev, Andrey B. Komissarov, Sophia S. Borisevich, Konstantin P. Volcho, Nariman F. Salakhutdinov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12933 (2023)
Respiratory syncytial virus (RSV) is known to cause annual epidemics of respiratory infections; however, the lack of specific treatment options for this disease poses a challenge. In light of this, there has been a concerted effort to identify small
Externí odkaz:
https://doaj.org/article/cdc8aff3f8404ae59ef6231cce3e147f
Autor:
Elena K. Kokinos, Sergey A. Tsymbal, Anastasia V. Galochkina, Svetlana A. Bezlepkina, Julia V. Nikolaeva, Sofia O. Vershinina, Anna A. Shtro, Victor V. Tatarskiy, Alexander A. Shtil, Eugenia V. Broude, Igor B. Roninson, Marina Dukhinova
Publikováno v:
Viruses, Vol 15, Iss 6, p 1292 (2023)
Hyperactivation of the immune system remains a dramatic, life-threatening complication of viral and bacterial infections, particularly during pneumonia. Therapeutic approaches to counteract local and systemic outbreaks of cytokine storm and to preven
Externí odkaz:
https://doaj.org/article/19250ae8ae084306bf89ae07e22bdecc
Autor:
Tatyana M. Khomenko, Anna A. Shtro, Anastasia V. Galochkina, Yulia V. Nikolaeva, Anzhelika V. Garshinina, Sophia S. Borisevich, Dina V. Korchagina, Konstantin P. Volcho, Nariman F. Salakhutdinov
Publikováno v:
Molecules, Vol 28, Iss 6, p 2673 (2023)
Respiratory syncytial virus (RSV) causes annual epidemics of respiratory infection. Usually harmless to adults, the RSV infection can be dangerous to children under 3 years of age and elderly people over 65 years of age, often causing serious problem
Externí odkaz:
https://doaj.org/article/f898cdbdf8014486be3e9f218ed2e56f
Autor:
Anastasiya S. Sokolova, Olga I. Yarovaya, Lana V. Kuzminykh, Anna A. Shtro, Artem M. Klabukov, Anastasia V. Galochkina, Yulia V. Nikolaeva, Galina D. Petukhova, Sophia S. Borisevich, Edward M. Khamitov, Nariman F. Salakhutdinov
Publikováno v:
Pharmaceuticals, Vol 15, Iss 11, p 1390 (2022)
Respiratory syncytial virus (RSV) causes acute respiratory infections, thus, posing a serious threat to the health of infants, children, and elderly people. In this study, we have discovered a series of potent RSV entry inhibitors with the (-)-borneo
Externí odkaz:
https://doaj.org/article/0f1616c0654d4805a855279093cc914a
Autor:
Tatyana M. Khomenko, Anna A. Shtro, Anastasia V. Galochkina, Yulia V. Nikolaeva, Galina D. Petukhova, Sophia S. Borisevich, Dina V. Korchagina, Konstantin P. Volcho, Nariman F. Salakhutdinov
Publikováno v:
Molecules, Vol 26, Iss 24, p 7493 (2021)
Respiratory syncytial virus (RSV) is a critical cause of infant mortality. However, there are no vaccines and adequate drugs for its treatment. We showed, for the first time, that O-linked coumarin–monoterpene conjugates are effective RSV inhibitor
Externí odkaz:
https://doaj.org/article/e5e7a134896b4c53a951294e02ba79f7
Autor:
Albina V. Dogadina, Vitali M. Boitsov, Julia L. Piterskaia, Anton A. Kornev, Yulia V. Nikolaeva, A. A. Babushkina, Anastasia V. Galochkina, Anna A. Shtro, D. M. Egorov
Publikováno v:
Medicinal Chemistry Research. 30:2203-2215
A series of 3-phosphonylated thiazolo[3,2-a]oxopyrimidines 3a-k was synthesized for the first time by the reactions of chloroethynylphosphonates with 5,6-disubstituted 2-thiouracils. In vitro antiviral activities have shown that the compounds 1i, 1j,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c664fc4f3bfce438b078051681fa3af7
https://doi.org/10.1007/s00044-021-02801-x
https://doi.org/10.1007/s00044-021-02801-x
Autor:
Galina A. Triandafilova, Svetlana O. Kushch, Yanina V. Burgart, Yulia V. Nikolaeva, Iana L. Esaulkova, Ekaterina I. Yakovleva, Ekaterina O. Sinegubova, Anastasia V. Galochkina, Vladimir V. Zarubaev, Olga P. Krasnykh, Victor I. Saloutin, Marina A. Ezhikova, Pavel A. Slepukhin, Anna A. Shtro, M. V. Goryaeva, Mikhail I. Kodess
Publikováno v:
Organic & Biomolecular Chemistry. 19:9925-9935
Heteroanalogs of ascidian alkaloids have been synthesized, and for the first time 10 different types of saturated carbo- and heteroannulated pyridones have been obtained. A new method for the formation of decahydro[1,3]oxazolo[2,3-j]quinoline and oct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f93cd04ad7687b5bd81f3d68e7fd0a
https://doi.org/10.1039/d1ob01843d
https://doi.org/10.1039/d1ob01843d
Autor:
Raylya R. Gabbasova, Roman S. Pavelyev, Denis Yu. Grishaev, Anastasia V. Galochkina, Raushan Nigmatullin, Petr Yablonskiy, Konstantin V. Balakin, Rail M. Khaziev, Olga Manicheva, Tatiana Vinogradova, Anna A. Shtro, Yulia V. Nikolaeva, Marine Dogonadze, Oleg Gnezdilov, E. G. Sokolovich, Yurii G. Shtyrlin, Nikita V. Shtyrlin
Publikováno v:
Letters in Drug Design & Discovery. 16:1360-1369
Background: Adamantane derivatives possess multiple pharmacological activities such as antiviral, anticancer, antimycobacterial, antidiabetic, antiparkinsonian and others. The interest of medicinal chemists in adamantane compounds is due to their uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b18484f80bd12df55986716eb6f2e3e0
https://doi.org/10.2174/1570180816666190911150705
https://doi.org/10.2174/1570180816666190911150705
Autor:
Elisaveta Gorbunova, Inna P. Tsypysheva, A. V. Koval’skaya, Vladimir V. Zarubaev, Sophia S. Borisevich, Dmitry O. Tsypyshev, P. R. Petrova, Anastasia V. Galochkina, Alexander N. Lobov, Victoria A. Fedorova
Publikováno v:
Tetrahedron. 75:2933-2943
The synthesis and anti-influenza activity study of Diels-Alder adducts of 3-N-substituted derivatives of (−)-cytisine with N-substituted maleimides are described. Synthesized compounds were studied for antiviral activity against influenza virus A/C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bd500d7652e40ecb276f6a50e897b25
https://doi.org/10.1016/j.tet.2019.04.021
https://doi.org/10.1016/j.tet.2019.04.021
Publikováno v:
European Journal of Medicinal Chemistry. 161:526-532
A novel chemotype topologically similar to known influenza virus PA endonuclease inhibitors has been designed. It was aimed to reproduce the extended topology of the known metal-chelating ligands with a p-phenylidene-linked bis-imidazoline scaffold.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e5b91e20db9f7fd34ae8753e5bf403
https://doi.org/10.1016/j.ejmech.2018.10.063
https://doi.org/10.1016/j.ejmech.2018.10.063