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Synthesis and cytotoxicity of novel simplified eleutherobin analogues as potential antitumour agents
Autor:
Yulia A. Gracheva, Vladimir A. Palyulin, Marina N. Semenova, Dmitry I. Osolodkin, Victor V. Semenov, Marina V. Proskurnina, Anastasia V Tutushkina, Alexander A. Shtil, Nikolay S. Zefirov, Valeria A. Glazunova, S. E. Sosonyuk, Dmitry A. Khlevin, N. A. Lozinskaya, Anita Peshich
Publikováno v:
Organicbiomolecular chemistry. 17(10)
Mixed simplified structures containing the paclitaxel and eleutherobin pharmacophore moieties were analyzed using molecular docking techniques and synthesized based on adamantane and 8-oxabicyclo[3.2.1]octane scaffolds. The crucial role of substituen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2025aa005a50f1c53dd46b38e6be2d4
https://pubmed.ncbi.nlm.nih.gov/30793716
https://pubmed.ncbi.nlm.nih.gov/30793716
