Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Anastasia Sowers"'
Autor:
Youji Hong, Yvette Robbins, Xinping Yang, Wojciech K. Mydlarz, Anastasia Sowers, James B. Mitchell, James L. Gulley, Jeffrey Schlom, Sofia R. Gameiro, Cem Sievers, Clint T. Allen
Publikováno v:
JCI Insight, Vol 7, Iss 5 (2022)
Therapeutic IL-12 has demonstrated the ability to reduce local immune suppression in preclinical models, but clinical development has been limited by severe inflammation-related adverse events with systemic administration. Here, we show that potent i
Externí odkaz:
https://doaj.org/article/087a78f2b3ee4f39ba65e786fa395d71
Autor:
James B. Mitchell, John A. Cook, Askale Mathias, Janet Gamson, Maria Wissler, Rajani Choudhuri, Anastasia Sowers, Sarwat Naz
Purpose: To characterize the ionizing radiation (IR) enhancing effects and underlying mechanisms of the CDK4/6 inhibitor abemaciclib in non–small cell lung cancer (NSCLC) cells in vitro and in vivo.Experimental Design: IR enhancement by abemaciclib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377a6d1429efe7eaaa181ddca8c16c7c
https://doi.org/10.1158/1078-0432.c.6528822
https://doi.org/10.1158/1078-0432.c.6528822
Autor:
Deborah E. Citrin, James Mitchell, Kevin Camphausen, Angela Thetford, Anastasia Sowers, Ayla White, Naamit Gerber, William P. Shield, Eun Joo Chung, Mary Ellen Urick
PDF file - 69K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21c76647e8d545551c181492a48ef94
https://doi.org/10.1158/1078-0432.22443156
https://doi.org/10.1158/1078-0432.22443156
Autor:
Deborah E. Citrin, James Mitchell, Kevin Camphausen, Angela Thetford, Anastasia Sowers, Ayla White, Naamit Gerber, William P. Shield, Eun Joo Chung, Mary Ellen Urick
PDF file - 69K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4620885418bd2b04aef78f7031714a61
https://doi.org/10.1158/1078-0432.22443159
https://doi.org/10.1158/1078-0432.22443159
Autor:
James B. Mitchell, John A. Cook, Askale Mathias, Janet Gamson, Maria Wissler, Rajani Choudhuri, Anastasia Sowers, Sarwat Naz
Figure S1. Radiation survival curve of H460 cells treated with Palbociclib (A) Ribociclib (B) and Abemaciclib (C) at a dose of 1µM and 10µM administered either 24 hour pre-or post for indicated dose (Gy) of radiation exposure. (D) Full dose surviva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7418025bb05a6810a893ff8370b2b5
https://doi.org/10.1158/1078-0432.22474578
https://doi.org/10.1158/1078-0432.22474578
Autor:
James B. Mitchell, John A. Cook, Askale Mathias, Janet Gamson, Maria Wissler, Rajani Choudhuri, Anastasia Sowers, Sarwat Naz
experimental methods and all supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb3e35a5ac2af2a594a674ce12cdbf1e
https://doi.org/10.1158/1078-0432.22474563.v1
https://doi.org/10.1158/1078-0432.22474563.v1
Autor:
James B. Mitchell, John A. Cook, Askale Mathias, Janet Gamson, Maria Wissler, Rajani Choudhuri, Anastasia Sowers, Sarwat Naz
excel file table showing details of microsatellite markers used for cell line authentication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a50c4ef4543ae4007c9eef943fff57
https://doi.org/10.1158/1078-0432.22474566
https://doi.org/10.1158/1078-0432.22474566
Autor:
Tiffany Toni, Ramya Viswanathan, Yvette Robbins, Sreenivasulu Gunti, Xinping Yang, Angel Huynh, Hui Cheng, Anastasia Sowers, James Mitchell, Clint Allen, Ethan Morgan, Carter Van Waes
Publikováno v:
Cancers; Volume 15; Issue 4; Pages: 1029
Head and neck squamous cell carcinoma (HNSCC) remains a prevalent diagnosis with current treatment options that include radiotherapy and immune-mediated therapies, in which tumor necrosis factor-α (TNFα) is a key mediator of cytotoxicity. However,
Autor:
Youji Hong, Yvette Robbins, Xinping Yang, Wojciech K. Mydlarz, Anastasia Sowers, James B. Mitchell, James L. Gulley, Jeffrey Schlom, Sofia R. Gameiro, Cem Sievers, Clint T. Allen
Publikováno v:
JCI insight. 7(5)
Therapeutic IL-12 has demonstrated the ability to reduce local immune suppression in preclinical models, but clinical development has been limited by severe inflammation-related adverse events with systemic administration. Here, we show that potent i
Autor:
Sandhya, Xavier, Ester, Piek, Makiko, Fujii, Delphine, Javelaud, Alain, Mauviel, Kathy C, Flanders, Ayelet M, Samuni, Angelina, Felici, Michael, Reiss, Shai, Yarkoni, Anastasia, Sowers, James B, Mitchell, Anita B, Roberts, Angelo, Russo
Publikováno v:
The Journal of biological chemistry. 279(15)
Radiation-induced fibrosis is an untoward effect of high dose therapeutic and inadvertent exposure to ionizing radiation. Transforming growth factor-beta (TGF-beta) has been proposed to be critical in tissue repair mechanisms resulting from radiation