Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Anastasia Mashukova"'
Publikováno v:
Biology Open, Vol 2, Iss 11, Pp 1264-1269 (2013)
Summary Components of the Par-complex, atypical PKC and Par3, have been found to be downregulated upon activation of NF-κB in intestinal epithelial cells. To determine their possible role in pro-inflammatory responses we transduced Caco-2 human colo
Externí odkaz:
https://doaj.org/article/6dd97eb4c8754721b69a6b37312bba75
Publikováno v:
Molecular Biology of the Cell
Par1b/MARK2 is a Ser/Thr kinase with pleiotropic effects that participates in the generation of apico-basal polarity in Caenorhabditis elegans. It is phosphorylated by atypical PKC(ι/λ) in Thr595 and inhibited. Because previous work showed a decrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36c49d6b788bd89fb197f40b819d390
https://pubmed.ncbi.nlm.nih.gov/33596087
https://pubmed.ncbi.nlm.nih.gov/33596087
Autor:
Pedro J.I. Salas, Radia Forteza, Maria M. Rodriguez, Nadia A. Ameen, Dmitri V. Kravtsov, Anastasia Mashukova
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 307:G992-G1001
Microvillus inclusion disease (MVID) is an autosomal recessive condition resulting in intractable secretory diarrhea in newborns due to loss-of-function mutations in myosin Vb (Myo5b). Previous work suggested that the apical recycling endosomal (ARE)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d08f1d972728f0009f138af61da6ef5
https://doi.org/10.1152/ajpgi.00180.2014
https://doi.org/10.1152/ajpgi.00180.2014
Publikováno v:
Biology Open
Biology Open, Vol 2, Iss 12, Pp 1425-1425 (2013)
Biology Open, Vol 2, Iss 11, Pp 1264-1269 (2013)
Biology Open, Vol 2, Iss 12, Pp 1425-1425 (2013)
Biology Open, Vol 2, Iss 11, Pp 1264-1269 (2013)
Summary Components of the Par-complex, atypical PKC and Par3, have been found to be downregulated upon activation of NF-κB in intestinal epithelial cells. To determine their possible role in pro-inflammatory responses we transduced Caco-2 human colo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2fbb8af11cff29ab12e42fc7260bef9
https://doi.org/10.1242/bio.20135918
https://doi.org/10.1242/bio.20135918
Publikováno v:
Molecular Biology of the Cell
Atypical PKC, Par6, and Par3 constitute a conserved complex signaling cell asymmetry. In contrast to its role in other tissues, atypical PKC inhibits NF-κB activation in epithelia and may function in maintaining low levels of inflammation in additio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253411437c31bcfe831bdf57034653a9
https://pubmed.ncbi.nlm.nih.gov/27226486
https://pubmed.ncbi.nlm.nih.gov/27226486
Publikováno v:
Tissue Barriers
As multicellular organisms evolved a family of cytoskeletal proteins, the keratins (types I and II) expressed in epithelial cells diversified in more than 20 genes in vertebrates. There is no question that keratin filaments confer mechanical stiffnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e598cad788400f3b31b2080c9921aa6b
https://pubmed.ncbi.nlm.nih.gov/27583190
https://pubmed.ncbi.nlm.nih.gov/27583190
Publikováno v:
Methods in enzymology. 569
A growing body of evidence from several laboratories points at non-mechanical functions of keratin intermediate filaments (IF), such as control of apoptosis, modulation of signaling, or regulation of innate immunity, among others. While these functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9c4ef9c4b8e48fe2baae071712e982f
https://pubmed.ncbi.nlm.nih.gov/26778557
https://pubmed.ncbi.nlm.nih.gov/26778557
Publikováno v:
Molecular Biology of the Cell
The polarity complex atypical PKC (aPKC) is rescued from degradation on intermediate filaments by Hsp70 chaperoning. The results indicate that PDK1 participates in the rescue mechanism and is localized to apical endosomes. Inhibition of dynamin-depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b426885fcfb554420456de82d50510c8
https://doi.org/10.1091/mbc.e11-12-0988
https://doi.org/10.1091/mbc.e11-12-0988
Autor:
Kai Stühler, Helmut E. Meyer, Heike Piechura, Nadine Stoepel, Daniela Brunert, Anastasia Mashukova, Eva M. Neuhaus, Bettina Warscheid, Hanns Hatt, Barbara Sitek, Jon Barbour
Publikováno v:
Journal of Proteome Research. 7:1594-1605
The olfactory system is exposed to a plethora of chemical compounds throughout an organism's lifespan. Anticipation of stimuli and construction of appropriate neural filters present a significant challenge. This may be addressed via modulation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5e60e3b27372464f28bafad0113b70
https://doi.org/10.1021/pr7005796
https://doi.org/10.1021/pr7005796
Publikováno v:
The Journal of Neuroscience. 26:9902-9912
Odorant receptors comprise the biggest subfamily of G-protein-coupled receptors. Although the endocytic mechanisms of other G-protein-coupled receptors have been characterized extensively, almost nothing is known about the intracellular trafficking o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a837296f8cf20927b804ad7665cc11
https://doi.org/10.1523/jneurosci.2897-06.2006
https://doi.org/10.1523/jneurosci.2897-06.2006