Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Anastasia Maria Zavitsanou"'
Autor:
Volkan I Sayin, Sarah E LeBoeuf, Simranjit X Singh, Shawn M Davidson, Douglas Biancur, Betul S Guzelhan, Samantha W Alvarez, Warren L Wu, Triantafyllia R Karakousi, Anastasia Maria Zavitsanou, Julian Ubriaco, Alexander Muir, Dimitris Karagiannis, Patrick J Morris, Craig J Thomas, Richard Possemato, Matthew G Vander Heiden, Thales Papagiannakopoulos
Publikováno v:
eLife, Vol 6 (2017)
During tumorigenesis, the high metabolic demand of cancer cells results in increased production of reactive oxygen species. To maintain oxidative homeostasis, tumor cells increase their antioxidant production through hyperactivation of the NRF2 pathw
Externí odkaz:
https://doaj.org/article/602ecca23db94613a5c1c6970c4e76e5
Autor:
Anastasia-Maria Zavitsanou, Ray Pillai, Yuan Hao, Warren L. Wu, Eric Bartnicki, Triantafyllia Karakousi, Sahith Rajalingam, Alberto Herrera, Angeliki Karatza, Ali Rashidfarrokhi, Sabrina Solis, Metamia Ciampricotti, Anna H. Yeaton, Ellie Ivanova, Corrin A. Wohlhieter, Terkild B. Buus, Makiko Hayashi, Burcu Karadal-Ferrena, Harvey I. Pass, John T. Poirier, Charles M. Rudin, Kwok-Kin Wong, Andre L. Moreira, Kamal M. Khanna, Aristotelis Tsirigos, Thales Papagiannakopoulos, Sergei B. Koralov
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113295- (2023)
Summary: Lung cancer treatment has benefited greatly through advancements in immunotherapies. However, immunotherapy often fails in patients with specific mutations like KEAP1, which are frequently found in lung adenocarcinoma. We established an anti
Externí odkaz:
https://doaj.org/article/240bdf74cb4547dea3fb1640afd7bcf5
Autor:
Sam Sheppard, Joana Guedes, Anna Mroz, Anastasia-Maria Zavitsanou, Hiromi Kudo, Stephen M. Rothery, Panagiotis Angelopoulos, Robert Goldin, Nadia Guerra
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Expression of NKG2D immunoreceptor ligands on tumour cells is believed to inhibit tumour growth through engaging NKG2D-expressing immune cells. Here, the authors show that in a model of liver cancer the NKG2D/NKG2D-ligand pathway can also promote tum
Externí odkaz:
https://doaj.org/article/19101936214342739334b5deafccc5f2
Autor:
Charles M. Rudin, Thales Papagiannakopoulos, John T. Poirier, Trudy G. Oliver, Triparna Sen, Mark T.A. Donoghue, Tyler Jacks, Elliot H. Akama-Garren, William M. Rideout, Andrea Ventura, Danilo Maddalo, Anastasia-Maria Zavitsanou, Janneke E. Jaspers, Francisco J. Sanchez-Rivera, Faruk E. Kombak, Kyle B. Spainhower, Parvathy Manoj, Viola Allaj, Emily A. Costa, Rebecca Caeser, Angeliki Karatza, Àlvaro Quintanal-Villalonga, Allison L. Richards, Triantafyllia Karakousi, Metamia Ciampricotti
Supplementary Figures S1 - S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e21dac3fbf8c8abfbd8d681c0ce639
https://doi.org/10.1158/2159-8290.22540609
https://doi.org/10.1158/2159-8290.22540609
Autor:
Leopoldo N. Segal, Thales Papagiannakopoulos, Kwok-Kin Wong, Richard Bonneau, Huilin Li, Jose C. Clemente, Harvey I. Pass, Daniel H. Sterman, William N. Rom, Adriana Heguy, Aristotelis Tsirigos, William Moore, Andre L. Moreira, Cynthia A. Loomis, Valeria Mezzano, Sergei B. Koralov, Anastasia-Maria Zavitsanou, Ray Pillai, Kevin Felner, Harald Sauthoff, Robert L. Smith, Jamie L. Bessich, Samaan Rafeq, Gaetane Michaud, Linchen He, Nan Shen, James T. Morton, Michelle Badri, Mariam El-Ashmawy, Tadasu Iizumi, Joseph Carpenito, Brendan Franca, Luisannay Perez, Evan Olsen, Peter Meyn, Ting-An Yie, Yonghua Li, Rosemary Schluger, Katherine Gershner, Imran Sulaiman, Benjamin G. Wu, Jun-Chieh J. Tsay
Supplementary Figure 1-23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45084f004644904ab2ad94b1c40f082a
https://doi.org/10.1158/2159-8290.22535168
https://doi.org/10.1158/2159-8290.22535168
Autor:
Leopoldo N. Segal, Thales Papagiannakopoulos, Kwok-Kin Wong, Richard Bonneau, Huilin Li, Jose C. Clemente, Harvey I. Pass, Daniel H. Sterman, William N. Rom, Adriana Heguy, Aristotelis Tsirigos, William Moore, Andre L. Moreira, Cynthia A. Loomis, Valeria Mezzano, Sergei B. Koralov, Anastasia-Maria Zavitsanou, Ray Pillai, Kevin Felner, Harald Sauthoff, Robert L. Smith, Jamie L. Bessich, Samaan Rafeq, Gaetane Michaud, Linchen He, Nan Shen, James T. Morton, Michelle Badri, Mariam El-Ashmawy, Tadasu Iizumi, Joseph Carpenito, Brendan Franca, Luisannay Perez, Evan Olsen, Peter Meyn, Ting-An Yie, Yonghua Li, Rosemary Schluger, Katherine Gershner, Imran Sulaiman, Benjamin G. Wu, Jun-Chieh J. Tsay
In lung cancer, enrichment of the lower airway microbiota with oral commensals commonly occurs, and ex vivo models support that some of these bacteria can trigger host transcriptomic signatures associated with carcinogenesis. Here, we show that this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4661dacabf76498f52c10e3d10efe956
https://doi.org/10.1158/2159-8290.c.6547772.v1
https://doi.org/10.1158/2159-8290.c.6547772.v1
Autor:
Leopoldo N. Segal, Thales Papagiannakopoulos, Kwok-Kin Wong, Richard Bonneau, Huilin Li, Jose C. Clemente, Harvey I. Pass, Daniel H. Sterman, William N. Rom, Adriana Heguy, Aristotelis Tsirigos, William Moore, Andre L. Moreira, Cynthia A. Loomis, Valeria Mezzano, Sergei B. Koralov, Anastasia-Maria Zavitsanou, Ray Pillai, Kevin Felner, Harald Sauthoff, Robert L. Smith, Jamie L. Bessich, Samaan Rafeq, Gaetane Michaud, Linchen He, Nan Shen, James T. Morton, Michelle Badri, Mariam El-Ashmawy, Tadasu Iizumi, Joseph Carpenito, Brendan Franca, Luisannay Perez, Evan Olsen, Peter Meyn, Ting-An Yie, Yonghua Li, Rosemary Schluger, Katherine Gershner, Imran Sulaiman, Benjamin G. Wu, Jun-Chieh J. Tsay
Supplementary File Table 1-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509ec0cdbe1fcc5c0d7d0a974f6ab8fd
https://doi.org/10.1158/2159-8290.22535165.v1
https://doi.org/10.1158/2159-8290.22535165.v1
Autor:
Leopoldo N. Segal, Thales Papagiannakopoulos, Kwok-Kin Wong, Richard Bonneau, Huilin Li, Jose C. Clemente, Harvey I. Pass, Daniel H. Sterman, William N. Rom, Adriana Heguy, Aristotelis Tsirigos, William Moore, Andre L. Moreira, Cynthia A. Loomis, Valeria Mezzano, Sergei B. Koralov, Anastasia-Maria Zavitsanou, Ray Pillai, Kevin Felner, Harald Sauthoff, Robert L. Smith, Jamie L. Bessich, Samaan Rafeq, Gaetane Michaud, Linchen He, Nan Shen, James T. Morton, Michelle Badri, Mariam El-Ashmawy, Tadasu Iizumi, Joseph Carpenito, Brendan Franca, Luisannay Perez, Evan Olsen, Peter Meyn, Ting-An Yie, Yonghua Li, Rosemary Schluger, Katherine Gershner, Imran Sulaiman, Benjamin G. Wu, Jun-Chieh J. Tsay
Supplementary Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4d3bab28bde65ec906d8c7d1902d7d
https://doi.org/10.1158/2159-8290.22535162
https://doi.org/10.1158/2159-8290.22535162
Autor:
Charles M. Rudin, Thales Papagiannakopoulos, John T. Poirier, Trudy G. Oliver, Triparna Sen, Mark T.A. Donoghue, Tyler Jacks, Elliot H. Akama-Garren, William M. Rideout, Andrea Ventura, Danilo Maddalo, Anastasia-Maria Zavitsanou, Janneke E. Jaspers, Francisco J. Sanchez-Rivera, Faruk E. Kombak, Kyle B. Spainhower, Parvathy Manoj, Viola Allaj, Emily A. Costa, Rebecca Caeser, Angeliki Karatza, Àlvaro Quintanal-Villalonga, Allison L. Richards, Triantafyllia Karakousi, Metamia Ciampricotti
Small cell lung cancer (SCLC) has limited therapeutic options and an exceptionally poor prognosis. Understanding the oncogenic drivers of SCLC may help define novel therapeutic targets. Recurrent genomic rearrangements have been identified in SCLC, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e119dfd0f00e496d01bd3fbdec93d54
https://doi.org/10.1158/2159-8290.c.6549427.v1
https://doi.org/10.1158/2159-8290.c.6549427.v1
Autor:
Ray Pillai, Sarah LeBoeuf, Ali Rashidfarrokhi, Shih Ming Huang, Triantafyllia Karakousi, Anastasia-Maria Zavitsanou, Warren Wu, Volkan Sayin, Robert Wild, Sergei Koralov, Thales Papagiannakopoulos
Publikováno v:
Cancer Research. 83:4904-4904
KEAP1 is mutated in approximately 20% of non-small cell lung cancer (NSCLC) and is associated with poor response rates to checkpoint blockade. Given the therapeutic challenge presented by KEAP1 mutant tumors and the great potential held by immunother