Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Anastasia M. Lopez"'
Autor:
Philip Jones, Nancy E. Kohl, Timothy P. Heffernan, Joseph R. Marszalek, Giulio F. Draetta, Andy M. Zuniga, Simon S. Yu, Christopher C. Williams, Erika Suzuki, Nakia D. Spencer, Sahil Seth, Vandhana Ramamoorthy, Michael Peoples, Robert A. Mullinax, Meredith A. Miller, Timothy McAfoos, Pijus K. Mandal, Xiaoyan Ma, Anastasia M. Lopez, Chiu-Yi Liu, Jeffrey J. Kovacs, Zhijun Kang, Yongying Jiang, Justin K. Huang, Virginia Giuliani, Sonal Gera, Guang Gao, Ningping Feng, Qing Chang, Christopher L. Carroll, Caroline C. Carrillo, Jason P. Burke, Christopher A. Bristow, Benjamin J. Bivona, Maria Emilia Di Francesco, Jason B. Cross, Connor A. Parker, Sarah Johnson, Qi Wu, Angela L. Harris, Faika Mseeh, Paul Leonard, Barbara Czako, Brooke A. Meyers, Yuting Sun
Src homology 2 domain-containing phosphatase (SHP2) is a phosphatase that mediates signaling downstream of multiple receptor tyrosine kinases (RTK) and is required for full activation of the MAPK pathway. SHP2 inhibition has demonstrated tumor growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679aa5c2787960118aa25b0d20d0a771
https://doi.org/10.1158/0008-5472.c.6512119.v1
https://doi.org/10.1158/0008-5472.c.6512119.v1
Autor:
Philip Jones, Nancy E. Kohl, Timothy P. Heffernan, Joseph R. Marszalek, Giulio F. Draetta, Andy M. Zuniga, Simon S. Yu, Christopher C. Williams, Erika Suzuki, Nakia D. Spencer, Sahil Seth, Vandhana Ramamoorthy, Michael Peoples, Robert A. Mullinax, Meredith A. Miller, Timothy McAfoos, Pijus K. Mandal, Xiaoyan Ma, Anastasia M. Lopez, Chiu-Yi Liu, Jeffrey J. Kovacs, Zhijun Kang, Yongying Jiang, Justin K. Huang, Virginia Giuliani, Sonal Gera, Guang Gao, Ningping Feng, Qing Chang, Christopher L. Carroll, Caroline C. Carrillo, Jason P. Burke, Christopher A. Bristow, Benjamin J. Bivona, Maria Emilia Di Francesco, Jason B. Cross, Connor A. Parker, Sarah Johnson, Qi Wu, Angela L. Harris, Faika Mseeh, Paul Leonard, Barbara Czako, Brooke A. Meyers, Yuting Sun
Supplementary Materials and Methods Supplementary References Tables S1 to S3 and legends Figures S1 to S4 and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb5082d82bd02f09e6060ee7ba89279
https://doi.org/10.1158/0008-5472.22425706.v1
https://doi.org/10.1158/0008-5472.22425706.v1
Autor:
Krishnan K. Mahadevan, Kathleen M. McAndrews, Valerie S. LeBleu, Sujuan Yang, Hengyu Lyu, Bingrui Li, Amari M. Sockwell, Michelle L. Kirtley, Sami J. Morse, Barbara A. Moreno Diaz, Michael P. Kim, Ningping Feng, Anastasia M. Lopez, Paola A. Guerrero, Hikaru Sugimoto, Kent A. Arian, Haoqiang Ying, Yasaman Barekatain, Patience J. Kelly, Anirban Maitra, Timothy P. Heffernan, Raghu Kalluri
Publikováno v:
bioRxiv
Pancreatic ductal adenocarcinoma (PDAC) is associated with mutations in Kras, a known oncogenic driver of PDAC; and theKRASG12Dmutation is present in nearly half of PDAC patients. Recently, a non-covalent small molecule inhibitor (MRTX1133) was ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ea79611c3fdc6d33522b958197d67c
https://doi.org/10.1101/2023.02.15.528757
https://doi.org/10.1101/2023.02.15.528757
Autor:
Qing Chang, Simon S. Yu, Christopher A. Bristow, Meredith A. Miller, Pijus K. Mandal, Yongying Jiang, Maria Emilia Di Francesco, Angela L. Harris, Christopher Carroll, Jason P Burke, Brooke A. Meyers, Zhijun Kang, Erika Suzuki, Cross Jason, Qi Wu, Connor A. Parker, Timothy McAfoos, Guang Gao, Sarah B. Johnson, Nancy E. Kohl, Ningping Feng, Yuting Sun, Chiu Yi Liu, Caroline C. Carrillo, Andy M. Zuniga, Paul G. Leonard, Sahil Seth, Virginia Giuliani, Faika Mseeh, Timothy P. Heffernan, Jeffrey J. Kovacs, Joseph R. Marszalek, Barbara Czako, Justin K. Huang, Giulio Draetta, Christopher C. Williams, Xiaoyan Ma, Anastasia M. Lopez, Nakia D. Spencer, Robert A. Mullinax, Vandhana Ramamoorthy, Philip Jones, Sonal Gera, Benjamin J. Bivona, Michael Peoples
Publikováno v:
Cancer research. 80(21)
Src homology 2 domain-containing phosphatase (SHP2) is a phosphatase that mediates signaling downstream of multiple receptor tyrosine kinases (RTK) and is required for full activation of the MAPK pathway. SHP2 inhibition has demonstrated tumor growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614d2e4bc8f9b4ddee8a36ce57a0dcd4
https://pubmed.ncbi.nlm.nih.gov/32928921
https://pubmed.ncbi.nlm.nih.gov/32928921
