Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Anastasia Lomova"'
Autor:
Elizabeth K. Benitez, Anastasia Lomova Kaufman, Lilibeth Cervantes, Danielle N. Clark, Paul G. Ayoub, Shantha Senadheera, Kyle Osborne, Julie M. Sanchez, Ralph Valentine Crisostomo, Xiaoyan Wang, Nina Reuven, Yosef Shaul, Roger P. Hollis, Zulema Romero, Donald B. Kohn
Publikováno v:
Frontiers in Genome Editing, Vol 2 (2020)
Monogenic disorders of the blood system have the potential to be treated by autologous stem cell transplantation of ex vivo genetically modified hematopoietic stem and progenitor cells (HSPCs). The sgRNA/Cas9 system allows for precise modification of
Externí odkaz:
https://doaj.org/article/e020611151d74c03b1efb0d76272a5c3
Autor:
Nicholas A Graham, Aspram Minasyan, Anastasia Lomova, Ashley Cass, Nikolas G Balanis, Michael Friedman, Shawna Chan, Sophie Zhao, Adrian Delgado, James Go, Lillie Beck, Christian Hurtz, Carina Ng, Rong Qiao, Johanna ten Hoeve, Nicolaos Palaskas, Hong Wu, Markus Müschen, Asha S Multani, Elisa Port, Steven M Larson, Nikolaus Schultz, Daniel Braas, Heather R Christofk, Ingo K Mellinghoff, Thomas G Graeber
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 2, Pp 1-25 (2017)
Abstract Copy number alteration (CNA) profiling of human tumors has revealed recurrent patterns of DNA amplifications and deletions across diverse cancer types. These patterns are suggestive of conserved selection pressures during tumor evolution but
Externí odkaz:
https://doaj.org/article/ecca9cc2cad345a0a0b562644ca81d88
Autor:
Shantha Senadheera, Julie M. Sanchez, Paul G. Ayoub, Nina Reuven, Danielle N. Clark, Zulema Romero, Donald B. Kohn, Elizabeth K. Benitez, Anastasia Lomova Kaufman, Roger P. Hollis, Ralph Valentine Crisostomo, Lilibeth Cervantes, Kyle Osborne, Yosef Shaul, Xiaoyan Wang
Publikováno v:
Frontiers in Genome Editing, Vol 2 (2020)
Frontiers in Genome Editing
Frontiers in Genome Editing
Monogenic disorders of the blood system have the potential to be treated by autologous stem cell transplantation of ex vivo genetically modified hematopoietic stem and progenitor cells (HSPCs). The sgRNA/Cas9 system allows for precise modification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f4d1d455b4aa2cff2cd59d20350b97
https://doi.org/10.3389/fgeed.2020.601541
https://doi.org/10.3389/fgeed.2020.601541
Publikováno v:
Cell stem cell, vol 21, iss 5
The use of allogeneic hematopoietic stem cells (HSCs) to treat genetic blood cell diseases has become a clinical standard but is limited by the availability of suitable matched donors and potential immunologic complications. Gene therapy using autolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078c3febbd69c5dab700939954a4338c
https://doi.org/10.1016/j.stem.2017.10.010
https://doi.org/10.1016/j.stem.2017.10.010
Autor:
Eric Miyahira, Donald B. Kohn, Danielle N. Clark, Joseph Long, Caroline Y. Kuo, Katelyn E. Masiuk, Zulema Romero, Yerbol Z. Kurmangaliyev, Beatriz Campo-Fernandez, Julie M. Sanchez, Ruixue Zhang, Suzanne Said, Anastasia Lomova, Alexandra Miggelbrink, Megan D. Hoban, Xiaoyan Wang, Roger P. Hollis, Devin Brown, Miriam Velez
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy, vol 27, iss 8
Mol Ther
Mol Ther
Site-specific correction of a point mutation causing a monogenic disease in autologous hematopoietic stem and progenitor cells (HSPCs) can be used as a treatment of inherited disorders of the blood cells. Sickle cell disease (SCD) is an ideal model t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::562e02d2604c4665940c8b4a73f1699e
https://escholarship.org/uc/item/6802h9n8
https://escholarship.org/uc/item/6802h9n8
Autor:
Beatriz Campo-Fernandez, Devin Brown, Zulema Romero, Sorel Fitz-Gibbon, Carmen Flores‐Bjurström, Jacob E. Corn, Roger P. Hollis, Mark A. DeWitt, Danielle N. Clark, Michael L. Kaufman, Xiaoyan Wang, Anastasia Lomova, Eric Miyahira, Donald B. Kohn
Publikováno v:
Stem cells (Dayton, Ohio), vol 37, iss 2
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated system (Cas9)-mediated gene editing of human hematopoietic stem cells (hHSCs) is a promising strategy for the treatment of genetic blood diseases through site-specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19b41d75376759f82855f312be00e4c
https://europepmc.org/articles/PMC6368869/
https://europepmc.org/articles/PMC6368869/
Autor:
Nikolaus Schultz, Michael C. Friedman, Carina Ng, Johanna ten Hoeve, Nicholas A. Graham, Hong Wu, Nikolas G. Balanis, Anastasia Lomova, Daniel Braas, Sophie Zhao, James Go, Ashley A. Cass, Rong Qiao, Christian Hurtz, Thomas G. Graeber, Adrian Delgado, Shawna Chan, Markus Müschen, Elisa Port, Nicolaos Palaskas, Aspram Minasyan, Steven M. Larson, Lillie Beck, Heather R. Christofk, Ingo K. Mellinghoff, Asha S. Multani
Publikováno v:
Molecular systems biology, vol 13, iss 2
Molecular Systems Biology
Molecular Systems Biology
Copy number alteration (CNA) profiling of human tumors has revealed recurrent patterns of DNA amplifications and deletions across diverse cancer types. These patterns are suggestive of conserved selection pressures during tumor evolution but cannot b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f716fc6b11a8964bca84976afd8ddc05
https://escholarship.org/uc/item/6vs2896r
https://escholarship.org/uc/item/6vs2896r
Autor:
Charles Ng, Bjoern Titz, Amanda Lassen, Antoni Ribas, Michael C. Friedman, Jennifer Tsoi, Bartosz Chmielowski, Anastasia Lomova, Thomas G. Graeber, Mohammad Atefi, Allison Le, Earl Avramis
Publikováno v:
Scientific reports, vol 6, iss 1
Scientific Reports
Scientific Reports
Approximately 75% of melanomas have known driver oncogenic mutations in BRAF, NRAS, GNA11 or GNAQ, while the mutations providing constitutive oncogenic signaling in the remaining melanomas are not known. We established a melanoma cell line from a tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde1a597fb975dc580ad084e212c0c30
https://escholarship.org/uc/item/1p19106w
https://escholarship.org/uc/item/1p19106w
Publikováno v:
Medical news of the North Caucasus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b4dbe1243665feb2600f1494db0c0e5
https://doi.org/10.14300/mnnc.2016.00096
https://doi.org/10.14300/mnnc.2016.00096
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