Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Anastasia L. Khandazhinskaya"'
Autor:
Alexander Yu Rudenko, Sofia S. Mariasina, Anastasiia K. Bolikhova, Maxim V. Nikulin, Ratislav M. Ozhiganov, Vasiliy G. Vasil’ev, Yuri A. Ikhalaynen, Anastasia L. Khandazhinskaya, Maxim A. Khomutov, Peter V. Sergiev, Alex R. Khomutov, Vladimir I. Polshakov
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
S-Adenosyl-l-methionine (SAM)-mediated methylation of biomolecules controls their function and regulates numerous vital intracellular processes. Analogs of SAM with a reporter group in place of the S-methyl group are widely used to study these proces
Externí odkaz:
https://doaj.org/article/77e58f40aa35434d87abbb35bd6ea9be
Derivatives of Pyrimidine Nucleosides Affect Artificial Membranes Enriched with Mycobacterial Lipids
Autor:
Olga S. Ostroumova, Svetlana S. Efimova, Polina D. Zlodeeva, Liudmila A. Alexandrova, Dmitry A. Makarov, Elena S. Matyugina, Vera A. Sokhraneva, Anastasia L. Khandazhinskaya, Sergey N. Kochetkov
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1110 (2024)
The mechanisms of action of pyrimidine nucleoside derivatives on model lipid membranes of various compositions were studied. A systematic analysis of the tested agents’ effects on the membrane physicochemical properties was performed. Differential
Externí odkaz:
https://doaj.org/article/b66b0686a2264f98ad282d3178176a2e
Autor:
Barbara Z. Eletskaya, Anton F. Mironov, Ilya V. Fateev, Maria Ya. Berzina, Konstantin V. Antonov, Olga S. Smirnova, Alexandra B. Zatsepina, Alexandra O. Arnautova, Yulia A. Abramchik, Alexander S. Paramonov, Alexey L. Kayushin, Anastasia L. Khandazhinskaya, Elena S. Matyugina, Sergey N. Kochetkov, Anatoly I. Miroshnikov, Igor A. Mikhailopulo, Roman S. Esipov, Irina D. Konstantinova
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 798 (2024)
Enzymatic transglycosylation of the fleximer base 4-(4-aminopyridine-3-yl)-1H-pyrazole using recombinant E. coli purine nucleoside phosphorylase (PNP) resulted in the formation of “non-typical” minor products of the reaction. In addition to “ty
Externí odkaz:
https://doaj.org/article/6dc5ba4973204c2f85cf40e3a5e85b6f
Autor:
Liudmila A. Alexandrova, Anastasia L. Khandazhinskaya, Elena S. Matyugina, Dmitriy A. Makarov, Sergey N. Kochetkov
Publikováno v:
Microorganisms, Vol 10, Iss 7, p 1299 (2022)
Tuberculosis (TB) is the oldest human infection disease. Mortality from TB significantly decreased in the 20th century, because of vaccination and the widespread use of antibiotics. However, about a third of the world’s population is currently infe
Externí odkaz:
https://doaj.org/article/7dd3191d86834485989b480b1c67b88a
Autor:
Vasily A. Kezin, Elena S. Matyugina, Mikhail S. Novikov, Alexander O. Chizhov, Robert Snoeck, Graciela Andrei, Sergei N. Kochetkov, Anastasia L. Khandazhinskaya
Publikováno v:
Molecules, Vol 27, Iss 9, p 2866 (2022)
Pyrimidine nucleoside analogues are widely used to treat infections caused by the human immunodeficiency virus (HIV) and DNA viruses from the herpes family. It has been shown that 5-substituted uracil derivatives can inhibit HIV-1, herpes family viru
Externí odkaz:
https://doaj.org/article/ba7d97f4d9c742ed9afcdcc355080063
Autor:
Anna A. Maslova, Elena S. Matyugina, Robert Snoeck, Graciela Andrei, Sergey N. Kochetkov, Anastasia L. Khandazhinskaya, Mikhail S. Novikov
Publikováno v:
Molecules, Vol 25, Iss 15, p 3350 (2020)
Widespread latent herpes viral infections within a population can lead to the development of co-infections in HIV-infected patients. These infections are not particularly dangerous for healthy individuals and often occur with minimal symptoms, but fo
Externí odkaz:
https://doaj.org/article/66eefd2c585745748102f251bc4fdaf6
Autor:
Anastasia L. Khandazhinskaya, Elena S. Matyugina, Pavel N. Solyev, Maggie Wilkinson, Karen W. Buckheit, Robert W. Buckheit, Larisa N. Chernousova, Tatiana G. Smirnova, Sofya N. Andreevskaya, Khalid J. Alzahrani, Manal J. Natto, Sergey N. Kochetkov, Harry P. de Koning, Katherine L. Seley-Radtke
Publikováno v:
Molecules, Vol 24, Iss 19, p 3433 (2019)
Carbocyclic nucleosides have long played a role in antiviral, antiparasitic, and antibacterial therapies. Recent results from our laboratories from two structurally related scaffolds have shown promising activity against both Mycobacterium tuberculos
Externí odkaz:
https://doaj.org/article/a637c58484344774bb35089123f966d7
Autor:
Anastasia L. Khandazhinskaya, Liudmila A. Alexandrova, Elena S. Matyugina, Pavel N. Solyev, Olga V. Efremenkova, Karen W. Buckheit, Maggie Wilkinson, Robert W. Buckheit, Larisa N. Chernousova, Tatiana G. Smirnova, Sofya N. Andreevskaya, Olga G. Leonova, Vladimir I. Popenko, Sergey N. Kochetkov, Katherine L. Seley-Radtke
Publikováno v:
Molecules, Vol 23, Iss 12, p 3069 (2018)
A series of novel 5′-norcarbocyclic derivatives of 5-alkoxymethyl or 5-alkyltriazolyl-methyl uracil were synthesized and the activity of the compounds evaluated against both Gram-positive and Gram-negative bacteria. The growth of Mycobacterium smeg
Externí odkaz:
https://doaj.org/article/df8f90d82864430ebc867f93b84c24a6
Autor:
Anna A. Klimenko, Elena S. Matyugina, Evgeniya B. Logashenko, Pavel N. Solyev, Marina A. Zenkova, Sergey N. Kochetkov, Anastasia L. Khandazhinskaya
Publikováno v:
Molecules, Vol 23, Iss 10, p 2654 (2018)
Here we report the synthesis and biological activity of new 5′-norcarbocyclic derivatives of bicyclic pyrrolo- and furano[2,3-d]pyrimidines with different substituents in the heterocyclic ring. Lead compound 3i, containing 6-pentylphenyl substituen
Externí odkaz:
https://doaj.org/article/bd62b854daba4f88b774317fef51845e
Autor:
Elena S. Matyugina, Mikhail S. Novikov, Liubov I. Kozlovskaya, Victor P. Volok, Elena Y. Shustova, Aidar A. Ishmukhametov, Sergey N. Kochetkov, Anastasia L. Khandazhinskaya
Publikováno v:
Acta Naturae
The pandemic caused by the novel betacoronavirus SARS-CoV-2 has already claimed more than 3.5 million lives. Despite the development and use of anti-COVID-19 vaccines, the disease remains a major public health challenge throughout the world. Large-sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c58c64440d346e384b299cb259592e
https://doi.org/10.32607/actanaturae.11479
https://doi.org/10.32607/actanaturae.11479