Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Anastasia Krivoruchko"'
Autor:
Hulya Karaca, Murat Kaya, Handan Açelya Kapkac, Serkan Levent, Yusuf Ozkay, Secil Deniz Ozan, Jens Nielsen, Anastasia Krivoruchko
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Background Metabolic engineering enables the sustainable and cost-efficient production of complex chemicals. Efficient production of terpenes in Saccharomyces cerevisiae can be achieved by recruiting an intermediate of the mevalonate pathway
Externí odkaz:
https://doaj.org/article/a295840edbce4ef7bdd81a762e3bc912
Autor:
Tao Yu, Yongjin J. Zhou, Leonie Wenning, Quanli Liu, Anastasia Krivoruchko, Verena Siewers, Jens Nielsen, Florian David
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Production of chemicals by microbial fermentation is an economical alternative to chemical synthesis. Here the authors re-engineer the yeastS. cerevisiaeto produce the very long chain fatty alcohol docosanol by expressing a heterologous Mycobacteria
Externí odkaz:
https://doaj.org/article/36f3a67ebbcd46798748b17bc28b8b18
Autor:
Tao Yu, Yongjin J. Zhou, Leonie Wenning, Quanli Liu, Anastasia Krivoruchko, Verena Siewers, Jens Nielsen, Florian David
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications 8: Article number: 15587 (2017); Published: 26 May 2017, Updated: 13 July 2018 In the originally published version of this Article, financial support was not fully acknowledged. The PDF and HTML versions of the Article have now
Externí odkaz:
https://doaj.org/article/b7bc770f7e634861b917495da7c010c1
Autor:
Boyang Ji, Michael Krogh Jensen, Jay D. Keasling, Anastasia Krivoruchko, Emre Özdemir, Jiufu Qin, Jens Nielsen, Mette Kristensen, Yu Chen
Publikováno v:
Nature Catalysis. 4:498-509
Structurally complex and diverse polyamines and polyamine analogues are potential therapeutics and agrochemicals that can address grand societal challenges, for example, healthy ageing and sustainable food production. However, their structural comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6f904b78dcef2aefdf067123dd134b5
https://doi.org/10.1038/s41929-021-00631-z
https://doi.org/10.1038/s41929-021-00631-z
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 44:1065-1072
Beta-elemene, a sesquiterpene and the major component of the medicinal herb Curcuma wenyujin, has antitumor activity against various types of cancer and could potentially serve as a potent antineoplastic drug. However, its current mode of production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d058d2d7d6efbc671b2638eeac4b92a
https://doi.org/10.1007/s10295-017-1934-z
https://doi.org/10.1007/s10295-017-1934-z
Publikováno v:
Nature chemical biology. 16(2)
Phospholipids, the most abundant membrane lipid components, are crucial in maintaining membrane structures and homeostasis for biofunctions. As a structurally diverse and tightly regulated system involved in multiple organelles, phospholipid metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f73169da6e58de0ed740ce4eba44f5
https://pubmed.ncbi.nlm.nih.gov/31844304
https://pubmed.ncbi.nlm.nih.gov/31844304
Autor:
Yongjin J. Zhou, Martin Grininger, Jens Nielsen, Zongbao K. Zhao, Anastasia Krivoruchko, Zhiwei Zhu
Publikováno v:
Nature Chemical Biology. 13:360-362
Fungal type I fatty acid synthases (FASs) are mega-enzymes with two separated, identical compartments, in which the acyl carrier protein (ACP) domains shuttle substrates to catalytically active sites embedded in the chamber wall. We devised synthetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::844c1b654abe2c33ebfb38285b3c6c08
https://doi.org/10.1038/nchembio.2301
https://doi.org/10.1038/nchembio.2301
Publikováno v:
Biotechnology and Bioengineering. 113:1164-1170
Engineering industrial cell factories to effectively yield a desired product while dealing with industrially relevant stresses is usually the most challenging step in the development of industrial production of chemicals using microbial fermentation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9bcb13a23f2d88ea5da1986a9ae36d7
https://doi.org/10.1002/bit.25870
https://doi.org/10.1002/bit.25870
Publikováno v:
Metabolic Engineering. 28:28-42
Recent concerns over the sustainability of petrochemical-based processes for production of desired chemicals have fueled research into alternative modes of production. Metabolic engineering of microbial cell factories such as Saccharomyces cerevisiae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3247ad85ee44725c7e82542d7d668b39
https://doi.org/10.1016/j.ymben.2014.11.009
https://doi.org/10.1016/j.ymben.2014.11.009