Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Anastasia Korolj"'
Autor:
Anastasia Korolj, Rainer H. Kohler, Ella Scott, Elias A. Halabi, Kilean Lucas, Jonathan C.T. Carlson, Ralph Weissleder
Publikováno v:
Advanced Science, Vol 10, Iss 34, Pp n/a-n/a (2023)
Abstract Intravital microscopy (IVM) allows spatial and temporal imaging of different cell types in intact live tissue microenvironments. IVM has played a critical role in understanding cancer biology, invasion, metastases, and drug development. One
Externí odkaz:
https://doaj.org/article/9d1c2c10032546648813e41d837c3f55
Autor:
Ruoxiao Xie, Anastasia Korolj, Chuan Liu, Xin Song, Rick Xing Ze Lu, Boyang Zhang, Arun Ramachandran, Qionglin Liang, Milica Radisic
Publikováno v:
ACS Central Science, Vol 6, Iss 6, Pp 903-912 (2020)
Externí odkaz:
https://doaj.org/article/7249499fef4f43edb444a7e46ecab18b
Autor:
Milica Radisic, Qionglin Liang, Chuan Liu, Anastasia Korolj, Ruoxiao Xie, Boyang Zhang, Xin Song, Rick Xing Ze Lu, Arun Ramachandran
Publikováno v:
ACS Central Science
ACS Central Science, Vol 6, Iss 6, Pp 903-912 (2020)
ACS Central Science, Vol 6, Iss 6, Pp 903-912 (2020)
Kidney-on-a-chip devices may revolutionize the discovery of new therapies. However, fabricating a 3D glomerulus remains a challenge, due to a requirement for a microscale soft material with complex topography to support cell culture in a native confi
Autor:
Houman Savoji, Samad Ahadian, Yimu Zhao, Naimeh Rafatian, Mohammad Hossein Mohammadi, Milica Radisic, Masood Khaksar Toroghi, Erika Yan Wang, Anastasia Korolj
Publikováno v:
Biomaterials. 198:3-26
Cardiovascular disease is the leading cause of death worldwide. Although investment in drug discovery and development has been sky-rocketing, the number of approved drugs has been declining. Cardiovascular toxicity due to therapeutic drug use claims
Autor:
Milica Radisic, Boyang Zhang, Genevieve Conant, Anastasia Korolj, Locke Davenport Huyer, Yimu Zhao, Miles Montgomery, Stasja Drecun, Lewis A. Reis
Publikováno v:
ACS biomaterials scienceengineering. 2(5)
Polyester biomaterials are used in tissue engineering as scaffolds for implantation of tissues developed in vitro. An ideal biodegradable elastomer for cardiac tissue engineering exhibits a relatively low Young's modulus, with high elongation and ten
Publikováno v:
Advanced biology. 5(7)
A sound understanding of developmental biology is part of the foundation of effective stem cell-derived tissue engineering. Here, the key concepts of cardiac development that are successfully applied in a bioinspired approach to growing engineered ca
Publikováno v:
Nature Reviews Materials. 3:257-278
Predicting the effects of drugs before human clinical trials is at the heart of drug screening and discovery processes. The cost of drug discovery is steadily increasing owing to the limited predictability of 2D cell culture and animal models. The co
Publikováno v:
Current Opinion in Biomedical Engineering. 6:8-16
Vasculature is an essential component of physiologically relevant tissue, yet mimicking the native vasculature is an ongoing challenge in tissue engineering. Microfabrication may provide a solution. This technique allows for control of material desig
Autor:
Samad Ahadian, Erding Hu, Christian H. James, Nathaniel P. Smith, Irene Gu, Robert N. Willette, Claire Velikonja, Boyang Zhang, Milica Radisic, Anastasia Korolj, Carol Laschinger
Publikováno v:
Lab on a Chip. 18:3112-3128
Most kidney diseases begin with abnormalities in glomerular podocytes, motivating the need for podocyte models to study pathophysiological mechanisms and new treatment options. However, podocytes cultured in vitro face a limited ability to maintain a
Publikováno v:
Clinical Science. 131:1393-1404
Engineering functional cardiac tissues remains an ongoing significant challenge due to the complexity of the native environment. However, our growing understanding of key parameters of the in vivo cardiac microenvironment and our ability to replicate