Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anastasia K. Zaytseva"'
Autor:
Anastasia K. Zaytseva, Artem M. Kiselev, Alexander S. Boitsov, Yulia V. Fomicheva, Georgii S. Pavlov, Boris S. Zhorov, Anna A. Kostareva
Publikováno v:
Biochemistry and Biophysics Reports, Vol 30, Iss , Pp 101249- (2022)
Genetic variants in SCN5A gene were identified in patients with various arrhythmogenic conditions including Brugada syndrome. Despite significant progress of last decades in studying the molecular mechanism of arrhythmia-associated SCN5A mutations, t
Externí odkaz:
https://doaj.org/article/0767e6e17b27496b991e0a16f9540f31
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Over 1,500 missense variants of sodium channel hNav1.5, which are reported in the ClinVar database, are associated with cardiac diseases. For most of the variants, the clinical significance is uncertain (VUS), not provided (NP), or has conflicting in
Externí odkaz:
https://doaj.org/article/b8f1e60ccf4d4ba4a86b72243c8e92cc
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Motion transmission from voltage sensors to inactivation gates is an important problem in the general physiology of ion channels. In a cryo-EM structure of channel hNav1.5, residues N1736 and R1739 in the extracellular loop IVP2-S6 approach glutamate
Externí odkaz:
https://doaj.org/article/a35295a238c34c0d8e9cdadc249a5083
Autor:
Nataliia V. Katolikova, Aleksandr A. Khudiakov, Daria D. Shafranskaya, Andrey D. Prjibelski, Alexey E. Masharskiy, Mikael S. Mor, Alexey S. Golovkin, Anastasia K. Zaytseva, Irina E. Neganova, Evgeniya V. Efimova, Raul R. Gainetdinov, Anna B. Malashicheva
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1429
Elaboration of protocols for differentiation of human pluripotent stem cells to dopamine neurons is an important issue for development of cell replacement therapy for Parkinson’s disease. A number of protocols have been already developed; however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a615b5c1329254b15de9a3a513cafaf9
https://doi.org/10.3390/ijms24021429
https://doi.org/10.3390/ijms24021429
Autor:
Anastasia K, Zaytseva, Artem M, Kiselev, Alexander S, Boitsov, Yulia V, Fomicheva, Georgii S, Pavlov, Boris S, Zhorov, Anna A, Kostareva
Publikováno v:
Biochemistry and biophysics reports. 30
Genetic variants in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::908003a625fec91820d175bc74281dab
https://pubmed.ncbi.nlm.nih.gov/35300108
https://pubmed.ncbi.nlm.nih.gov/35300108
Autor:
Alexey V. Karpushev, Anna Kostareva, Evgeny N. Mikhaylov, Anastasia K Zaytseva, Dmitry S. Lebedev, Artem Kiselev, Boris S. Zhorov
Publikováno v:
Biochemical and Biophysical Research Communications. 516:777-783
Mutations in gene SCN5A, which encodes cardiac voltage-gated sodium channel Nav1.5, are associated with multiple clinical phenotypes. Here we describe a novel A1294G genetic variant detected in a male patient with combined clinical phenotype includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e608439e01605e7bd18f16b34395a6
https://doi.org/10.1016/j.bbrc.2019.06.080
https://doi.org/10.1016/j.bbrc.2019.06.080
Autor:
Aleksandr Khudiakov, Kseniya Perepelina, Anastasia K Zaytseva, Anna Kostareva, Elena Kaznacheyeva, Sofia Makeenok, Konstantin Gusev
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 4, Pp 696-706 (2020)
Background/aims Mutations of desmosomal genes are known to cause arrhythmogenic cardiomyopathy characterized by arrhythmias and sudden cardiac death. Previously, we described a novel genetic variant H1684R in desmoplakin gene (DSP), associated with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b479da686703605eb299996a3af7284
https://pubmed.ncbi.nlm.nih.gov/32706220
https://pubmed.ncbi.nlm.nih.gov/32706220
Autor:
Alexey Tomilin, Anna Kostareva, Elena Vasichkina, Tatiana Pervunina, Natalia Smolina, Anastasia K Zaytseva, Anna Malashicheva, Aleksandr Khudiakov, Kseniya Perepelina, Alexey V. Karpushev
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1866:165915
Background Mutations in desmosomal genes linked to arrhythmogenic cardiomyopathy are commonly associated with Wnt/β-catenin signaling abnormalities and reduction of the sodium current density. Inhibitors of GSK3B were reported to restore sodium curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41cdf72e75491d821d4669df4aebbbed
https://doi.org/10.1016/j.bbadis.2020.165915
https://doi.org/10.1016/j.bbadis.2020.165915