Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Anastasia Hyrina"'
Autor:
Anastasia Hyrina, Dara Burdette, Zhijuan Song, Ricardo Ramirez, Ayse Okesli-Armlovich, Archana Vijayakumar, Jamie Bates, James L. Trevaskis, Simon P. Fletcher, William A. Lee, Meghan M. Holdorf
Publikováno v:
PLoS ONE, Vol 17, Iss 8 (2022)
Chronic hepatitis B virus (HBV) infection is characterized by the presence of high circulating levels of non-infectious lipoprotein-like HBV surface antigen (HBsAg) particles thought to contribute to chronic immune dysfunction in patients. Lipid and
Externí odkaz:
https://doaj.org/article/5cb5456c3f804f678aceb51146756bf4
Autor:
Joshua R Kane, Susan Fong, Jacob Shaul, Alexandra Frommlet, Andreas O Frank, Mark Knapp, Dirksen E Bussiere, Peter Kim, Elizabeth Ornelas, Carlos Cuellar, Anastasia Hyrina, Johanna R Abend, Charles A Wartchow
Publikováno v:
eLife, Vol 9 (2020)
In pursuit of therapeutics for human polyomaviruses, we identified a peptide derived from the BK polyomavirus (BKV) minor structural proteins VP2/3 that is a potent inhibitor of BKV infection with no observable cellular toxicity. The thirteen-residue
Externí odkaz:
https://doaj.org/article/2b17b8ea557f438fa77b7135beaff218
Autor:
Anastasia Hyrina, Christopher Jones, Darlene Chen, Scott Clarkson, Nadire Cochran, Paul Feucht, Gregory Hoffman, Alicia Lindeman, Carsten Russ, Frederic Sigoillot, Tiffany Tsang, Kyoko Uehara, Lili Xie, Don Ganem, Meghan Holdorf
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 2970-2978.e6 (2019)
Summary: A hallmark of chronic hepatitis B (CHB) virus infection is the presence of high circulating levels of non-infectious small lipid HBV surface antigen (HBsAg) vesicles. Although rare, sustained HBsAg loss is the idealized endpoint of any CHB t
Externí odkaz:
https://doaj.org/article/1de14fd71bb445e89c5fdea311bfc65e
Publikováno v:
EBioMedicine, Vol 23, Iss C, Pp 68-78 (2017)
In patients with chronic hepatitis C virus (HCV) infection, viral hijacking of the host-cell biosynthetic pathways is associated with altered lipid metabolism, which contributes to disease progression and may influence antiviral response. We investig
Externí odkaz:
https://doaj.org/article/caa5f4c18f7441c4873a070f92ecc254
Autor:
Anastasia Hyrina, Fanrui Meng, Steven J McArthur, Sharlene Eivemark, Ivan R Nabi, François Jean
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174483 (2017)
Viral hijacking and manipulation of host-cell biosynthetic pathways by human enveloped viruses are shared molecular events essential for the viral lifecycle. For Flaviviridae members such as hepatitis C virus and dengue virus (DENV), one of the key s
Externí odkaz:
https://doaj.org/article/8fe6c0fce4544b1483d51d5be61ebc0d
Autor:
Julie Lucifora, Dulce Alfaiate, Caroline Pons, Maud Michelet, Ricardo Ramirez, Floriane Fusil, Fouzia Amirache, Axel Rossi, Anne-Flore Legrand, Emilie Charles, Serena Vegna, Rayan Farhat, Michel Rivoire, Guillaume Passot, Nicolas Gadot, Barbara Testoni, Charlotte Bach, Thomas F. Baumert, Anastasia Hyrina, Rudolf K. Beran, Fabien Zoulim, Andre Boonstra, Hildegard Büning, Eloi R. Verrier, François-Loïc Cosset, Simon P. Fletcher, Anna Salvetti, David Durantel
Publikováno v:
Journal of Hepatology
Journal of Hepatology, In press, ⟨10.1016/j.jhep.2023.01.005⟩
Journal of Hepatology, 78(5), 958-970. Elsevier
Journal of Hepatology, In press, ⟨10.1016/j.jhep.2023.01.005⟩
Journal of Hepatology, 78(5), 958-970. Elsevier
Background & Aims: Chronic coinfection with HBV and HDV leads to the most aggressive form of chronic viral hepatitis. Herein, we aimed to elucidate the molecular mechanisms underlying the widely reported observation that HDV interferes with HBV in mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3b3eff3a87ef013cb5c6dbae104bda
Autor:
Dara Burdette, Anastasia Hyrina, Zhijuan Song, Rudolf K. Beran, Tara Cheung, Sarah Gilmore, Tetsuya Kobayashi, Li Li, Yang Liu, Anita Niedziela-Majka, Jonathan Medley, Upasana Mehra, Philip Morganelli, Nikolai Novikov, Congrong Niu, Danny Tam, Jennifer Tang, Jianhong Wang, Qin Yue, Simon P. Fletcher, Meghan M. Holdorf, William E. Delaney, Becket Feierbach, Scott Lazerwith
Publikováno v:
Antimicrobial agents and chemotherapy.
The standard of care for the treatment of chronic hepatitis B (CHB) is typically lifelong treatment with nucleos(t)ide analogs (NAs), which suppress viral replication and provide long-term clinical benefits. However, infectious virus can still be det
Publikováno v:
Journal of Molecular Biology. :168042
Autor:
Ricardo Ramirez, Anastasia Hyrina, Rudolf Beran, Stephane Daffis, Sarah Gilmore, Don Kang, Noé Axel Montanari, Nicholas Van Buuren, Li Li, Dara Burdette, Becket Feierbach, Andre Boonstra, Simon Fletcher
Publikováno v:
Journal of Hepatology. 77:S251
Autor:
Shahed Iqbal, Ruidong Li, Silpa Suthram, Jeffrey Wallin, James Trevaskis, Anastasia Hyrina, Simon Fletcher, Meghan Holdorf
Publikováno v:
Journal of Hepatology. 77:S276