Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Anastasia E Kottorou"'
Autor:
Foteinos-Ioannis D. Dimitrakopoulos, Anna G. Antonacopoulou, Anastasia E. Kottorou, Melpomeni Kalofonou, Nikolaos Panagopoulos, Dimitrios Dougenis, Thomas Makatsoris, Vasiliki Tzelepi, Angelos Koutras, Haralabos P. Kalofonos
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundImmune system-related receptors CD40 (tumor necrosis factor receptor superfamily member 5), BAFFR (tumor necrosis factor receptor superfamily member 13C), and LTβR (tumor necrosis factor receptor superfamily member 3) play a pivotal role i
Externí odkaz:
https://doaj.org/article/c8a31c79958046baaea54e62931e3ee1
Autor:
Foteinos-Ioannis D. Dimitrakopoulos, Anna G. Antonacopoulou, Anastasia E. Kottorou, Nikolaos Panagopoulos, Fotini Kalofonou, Fotios Sampsonas, Chrisoula Scopa, Melpomeni Kalofonou, Angelos Koutras, Thomas Makatsoris, Dimitrios Dougenis, Helen Papadaki, Malcolm Brock, Haralabos P. Kalofonos
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract A growing number of studies has shed light on the role of the NF-κΒ in non-small-cell lung cancer (NSCLC). To address the significance of major effectors of the NF-κΒ alternative pathway, we investigated the relationship between NF-κΒ2
Externí odkaz:
https://doaj.org/article/90d7b523d73d42dd8591096c779df15c
Autor:
Anna Antonacopoulou, Anastasia E. Kottorou, Foteinos-Ioannis Dimitrakopoulos, Stella Marousi, Foteini Kalofonou, Angelos Koutras, Thomas Makatsoris, Vassiliki Tzelepi, Haralabos P. Kalofonos
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100912- (2021)
The Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) family of transcription factors plays an important role in immune responses and cancer development and progression. We have focused on NF-κB2 and RELB of the alternative pat
Externí odkaz:
https://doaj.org/article/11732b97e40845a4ad6406542d815274
Autor:
Haralabos P. Kalofonos, Melpomeni Kalofonou, Anastasia E. Kottorou, Foteinos-Ioannis D. Dimitrakopoulos
Supplementary Table S2. Published studies on genetic variations of NF-κB family members and their clinical significance in NSCLC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1c82c87ae3fcad35c49c464821cd3c
https://doi.org/10.1158/0008-5472.22425417.v1
https://doi.org/10.1158/0008-5472.22425417.v1
Autor:
Haralabos P. Kalofonos, Melpomeni Kalofonou, Anastasia E. Kottorou, Foteinos-Ioannis D. Dimitrakopoulos
Supplementary Figure S1. Hallmarks of lung cancer influenced by NF-κB activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6210ba999de79b46629e6b6e33336338
https://doi.org/10.1158/0008-5472.22425423
https://doi.org/10.1158/0008-5472.22425423
Autor:
Haralabos P. Kalofonos, Melpomeni Kalofonou, Anastasia E. Kottorou, Foteinos-Ioannis D. Dimitrakopoulos
Thirty-four years since its discovery, NF-κB remains a transcription factor with great potential for cancer therapy. However, NF-κB–targeted therapies have yet to find a way to be clinically translatable. Here, we focus exclusively on the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862f11defaddefc1eeefd9caa436adb8
https://doi.org/10.1158/0008-5472.c.6512031.v1
https://doi.org/10.1158/0008-5472.c.6512031.v1
Autor:
Foteinos-Ioannis Dimitrakopoulos, Anastasia E. Kottorou, Melpomeni Kalofonou, Haralabos P. Kalofonos
Publikováno v:
Cancer Research. 80:4025-4036
Thirty-four years since its discovery, NF-κB remains a transcription factor with great potential for cancer therapy. However, NF-κB–targeted therapies have yet to find a way to be clinically translatable. Here, we focus exclusively on the role of
Autor:
Foteinos-Ioannis D. Dimtrakopoulos, Petros Christopoulos, Mariam Elshiaty, Lea Daniello, Ioannis Pyrousis, Anastasia E Kottorou, Thomas Makatsoris, Haralabos Kalofonos, Angelos Koutras
Publikováno v:
Journal of Clinical Oncology. 40:e21096-e21096
e21096 Background: Ιmmune checkpoint inhibitors (ICIs) have tremendously changed the daily clinical practice on the treatment of advanced non-small cell lung cancer (aNSCLC). However, clinical useful biomarkers remain an unmet need. Recently, a new
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 7, Pp 101101-(2021)
Translational Oncology, Vol 14, Iss 7, Pp 101101-(2021)
Highlights • Cancer-associated cachexia is mainly characterized by skeletal muscle and adipose loss, release of pro-cachectic factors by cancer and immune cells and energy imbalance. • Cancer cachexia is prominent in many types of cancer and it i
Publikováno v:
Cancer letters. 517
Despite the enormous advances during the last three decades, breast cancer continues to be the most frequent type of cancer as well as one of the most frequent cancer-related causes of death in women. Therapeutic management of patients with hormone r