Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Anastasia Deckard"'
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-20 (2022)
Abstract Background Cell and circadian cycles control a large fraction of cell and organismal physiology by regulating large periodic transcriptional programs that encompass anywhere from 15 to 80% of the genome despite performing distinct functions.
Externí odkaz:
https://doaj.org/article/0f55cfa96ce9411ebaf32eda110b0971
Autor:
Breschine Cummins, Francis C Motta, Robert C Moseley, Anastasia Deckard, Sophia Campione, Marcio Gameiro, Tomáš Gedeon, Konstantin Mischaikow, Steven B Haase
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 10, p e1010145 (2022)
Large programs of dynamic gene expression, like cell cyles and circadian rhythms, are controlled by a relatively small "core" network of transcription factors and post-translational modifiers, working in concerted mutual regulation. Recent work sugge
Externí odkaz:
https://doaj.org/article/55e1e7261831478a89eda5fc425d2f41
Autor:
Breschine Cummins, Robert C. Moseley, Anastasia Deckard, Mark Weston, George Zheng, Daniel Bryce, Joshua Nowak, Marcio Gameiro, Tomas Gedeon, Konstantin Mischaikow, Jacob Beal, Tessa Johnson, Matthew Vaughn, Niall I. Gaffney, Shweta Gopaulakrishnan, Joshua Urrutia, Robert P. Goldman, Bryan Bartley, Tramy T. Nguyen, Nicholas Roehner, Tom Mitchell, Justin D. Vrana, Katie J. Clowers, Narendra Maheshri, Diveena Becker, Ekaterina Mikhalev, Vanessa Biggers, Trissha R. Higa, Lorraine A. Mosqueda, Steven B. Haase
A challenge in the design and construction of synthetic genetic circuits is that they will operate within biological systems that have noisy and changing parameter regimes that are largely unmeasurable. The outcome is that these circuits do not opera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acb350e59a276963ace339cc4381b44a
https://doi.org/10.1101/2022.06.13.495701
https://doi.org/10.1101/2022.06.13.495701
Autor:
Breschine Cummins, Justin Vrana, Robert C Moseley, Hamed Eramian, Anastasia Deckard, Pedro Fontanarrosa, Daniel Bryce, Mark Weston, George Zheng, Joshua Nowak, Francis C Motta, Mohammed Eslami, Kara Layne Johnson, Robert P Goldman, Chris J Myers, Tessa Johnson, Matthew W Vaughn, Niall Gaffney, Joshua Urrutia, Shweta Gopaulakrishnan, Vanessa Biggers, Trissha R Higa, Lorraine A Mosqueda, Marcio Gameiro, Tomáš Gedeon, Konstantin Mischaikow, Jacob Beal, Bryan Bartley, Tom Mitchell, Tramy T Nguyen, Nicholas Roehner, Steven B Haase
Computational tools addressing various components of design–build–test–learn (DBTL) loops for the construction of synthetic genetic networks exist but do not generally cover the entire DBTL loop. This manuscript introduces an end-to-end sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2c9b817f1b0a8d922071cda533d340
https://doi.org/10.1101/2022.06.10.495560
https://doi.org/10.1101/2022.06.10.495560
Autor:
Robert P. Goldman, Robert Moseley, Nicholas Roehner, Bree Cummins, Justin D. Vrana, Katie J. Clowers, Daniel Bryce, Jacob Beal, Matthew DeHaven, Joshua Nowak, Trissha Higa, Vanessa Biggers, Peter Lee, Jeremy P. Hunt, Lorraine Mosqueda, Steven B. Haase, Mark Weston, George Zheng, Anastasia Deckard, Shweta Gopaulakrishnan, Joseph F. Stubbs, Niall I. Gaffney, Matthew W. Vaughn, Narendra Maheshri, Ekaterina Mikhalev, Bryan Bartley, Richard Markeloff, Tom Mitchell, Tramy Nguyen, Daniel Sumorok, Nicholas Walczak, Chris Myers, Zach Zundel, Benjamin Hatch, James Scholz, John Colonna-Romano
We describe an experimental campaign that replicated the performance assessment of logic gates engineered into cells of S. cerevisiae by Gander, et al. Our experimental campaign used a novel high throughput experimentation framework developed under D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e5a6dae48c1a2cd916514191289c547
https://doi.org/10.1101/2022.05.31.493627
https://doi.org/10.1101/2022.05.31.493627
Autor:
Breschine Cummins, Francis C. Motta, Robert C. Moseley, Anastasia Deckard, Sophia Campione, Tomáš Gedeon, Konstantin Mischaikow, Steven B. Haase
Large programs of dynamic gene expression, like cell cyles and circadian rhythms, are controlled by a relatively small “core” network of transcription factors and post-translational modifiers, working in concerted mutual regulation. Recent work s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf3a46f588c12c372bb6291d1ca198b1
https://doi.org/10.1101/2022.04.28.489981
https://doi.org/10.1101/2022.04.28.489981
Autor:
Daniel Bryce, Robert P. Goldman, Matthew DeHaven, Jacob Beal, Bryan Bartley, Tramy T. Nguyen, Nicholas Walczak, Mark Weston, George Zheng, Josh Nowak, Peter Lee, Joe Stubbs, Niall Gaffney, Matthew W. Vaughn, Chris John Myers, Robert C. Moseley, Steven Haase, Anastasia Deckard, Bree Cummins, Nick Leiby
Publikováno v:
ACS synthetic biology. 11(2)
Synthetic biology is a complex discipline that involves creating detailed, purpose-built designs from genetic parts. This process is often phrased as a Design-Build-Test-Learn loop, where iterative design improvements can be made, implemented, measur
Autor:
Robert P Goldman, Robert Moseley, Nicholas Roehner, Breschine Cummins, Justin D Vrana, Katie J Clowers, Daniel Bryce, Jacob Beal, Matthew DeHaven, Joshua Nowak, Trissha Higa, Vanessa Biggers, Peter Lee, Jeremy P Hunt, Lorraine Mosqueda, Steven B Haase, Mark Weston, George Zheng, Anastasia Deckard, Shweta Gopaulakrishnan, Joseph F Stubbs, Niall I Gaffney, Matthew W Vaughn, Narendra Maheshri, Ekaterina Mikhalev, Bryan Bartley, Richard Markeloff, Tom Mitchell, Tramy Nguyen, Daniel Sumorok, Nicholas Walczak, Chris Myers, Zach Zundel, Benjamin Hatch, James Scholz, John Colonna-Romano
Publikováno v:
Synthetic Biology. 7
We describe an experimental campaign that replicated the performance assessment of logic gates engineered into cells of Saccharomyces cerevisiae by Gander et al. Our experimental campaign used a novel high-throughput experimentation framework develop
Autor:
Kevin McGoff, Francis C. Motta, John Harer, Kyle Cavanaugh, M. Anthony Moody, Steven B. Haase, Cameron R. Wolfe, Mattia Bonsignori, Anastasia Deckard, Thomas N. Denny
Publikováno v:
JAMA Health Forum
Key Points Question Are surveillance testing and quarantine still important for limiting virus transmission on college campuses where the student population is completely vaccinated against SARS-CoV-2? Findings In this decision analytical model study
Autor:
Kevin McGoff, M. Anthony Moody, Kyle Cavanaugh, Steven B. Haase, Thomas N. Denny, Cameron R. Wolfe, Francis C. Motta, John Harer, Anastasia Deckard
Surveillance testing and quarantine have been effective measures for limiting SARS-CoV-2 transmission on university campuses. However, the importance of these measures needs to be re-evaluated in the context of a complex and rapidly changing environm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c24f458b0c728434ff525001dffa9179
https://doi.org/10.1101/2021.06.15.21258928
https://doi.org/10.1101/2021.06.15.21258928