Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Anastasia D. Katsiampoura"'
Autor:
Davide Cattano, Peter V. Killoran, Chunyan Cai, Anastasia D. Katsiampoura, Ruggero M. Corso, Carin A. Hagberg
Publikováno v:
F1000Research, Vol 3 (2014)
Background: There are few predictors of difficult mask ventilation and a simple, objective, predictive system to identify patients at risk of difficult mask ventilation does not currently exist. We present a retrospective - subgroup analysis aimed at
Externí odkaz:
https://doaj.org/article/9b198df5b1324386a642001b93180072
Autor:
Scott Kopetz, Gary E. Gallick, Alain R. Thierry, Michael J. Overman, Cathy Eng, Robert A. Wolff, David G. Menter, Anastasia D. Katsiampoura, David R. Fogelman, Arvind Dasari, Kanwal Raghav, Marc Ychou, Brice Pastor, Feng Tian, Laura Henderson, Zhi-Qin Jiang, Ji Yuan Wu, Nila U. Parikh, Christine M. Parseghian
Purpose: Aberrant activation of the intracellular tyrosine kinase Src has been implicated as a mechanism of acquired chemotherapy resistance in metastatic colorectal cancer (mCRC). Here, the oral tyrosine kinase Src inhibitor, dasatinib, was investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493cba9094cd2e6c43821d133756c6a5
https://doi.org/10.1158/1078-0432.c.6526826
https://doi.org/10.1158/1078-0432.c.6526826
Autor:
Scott Kopetz, Marc Ychou, Safia El Messaoudi, Cynthia Sanchez, Michael J. Overman, Jonathan M. Loree, Christine Parseghian, Anastasia D. Katsiampoura, Zhi-Qin Jiang, Brice Pastor, Alain R. Thierry
Purpose: Liquid biopsies allow the tracking of clonal dynamics and detection of mutations during treatment.Experimental Design: We evaluated under blinded conditions the ability of cell-free DNA (cfDNA) to detect RAS/BRAF mutations in the plasma of 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7bc00964f6d5b3c18327e32f627eabf
https://doi.org/10.1158/1078-0432.c.6525203.v1
https://doi.org/10.1158/1078-0432.c.6525203.v1
Autor:
Scott Kopetz, Gary E. Gallick, Alain R. Thierry, Michael J. Overman, Cathy Eng, Robert A. Wolff, David G. Menter, Anastasia D. Katsiampoura, David R. Fogelman, Arvind Dasari, Kanwal Raghav, Marc Ychou, Brice Pastor, Feng Tian, Laura Henderson, Zhi-Qin Jiang, Ji Yuan Wu, Nila U. Parikh, Christine M. Parseghian
Validation of peripheral blood mononuclear cells as a biomarker of Src inhibition. Freshly collected peripheral blood mononuclear cells from a healthy volunteer were treated ex-vivo with dasatinib 300 nM or hydrogen peroxide 0.05 mM. The peripheral b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42048aa738ec1b6e17d9bcc70397504b
https://doi.org/10.1158/1078-0432.22468073
https://doi.org/10.1158/1078-0432.22468073
Autor:
Scott Kopetz, Gary E. Gallick, Alain R. Thierry, Michael J. Overman, Cathy Eng, Robert A. Wolff, David G. Menter, Anastasia D. Katsiampoura, David R. Fogelman, Arvind Dasari, Kanwal Raghav, Marc Ychou, Brice Pastor, Feng Tian, Laura Henderson, Zhi-Qin Jiang, Ji Yuan Wu, Nila U. Parikh, Christine M. Parseghian
Operating characteristics. A summary of the probability of stopping the trial early for the indicated true response rates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1507020a7c8559fc408126becd09af
https://doi.org/10.1158/1078-0432.22468061
https://doi.org/10.1158/1078-0432.22468061
Autor:
Scott Kopetz, Gary E. Gallick, Alain R. Thierry, Michael J. Overman, Cathy Eng, Robert A. Wolff, David G. Menter, Anastasia D. Katsiampoura, David R. Fogelman, Arvind Dasari, Kanwal Raghav, Marc Ychou, Brice Pastor, Feng Tian, Laura Henderson, Zhi-Qin Jiang, Ji Yuan Wu, Nila U. Parikh, Christine M. Parseghian
Supplemental material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39aa0ab58191ff5a8d7e882c49b26d1e
https://doi.org/10.1158/1078-0432.22468064.v1
https://doi.org/10.1158/1078-0432.22468064.v1
Autor:
Scott Kopetz, Gary E. Gallick, Alain R. Thierry, Michael J. Overman, Cathy Eng, Robert A. Wolff, David G. Menter, Anastasia D. Katsiampoura, David R. Fogelman, Arvind Dasari, Kanwal Raghav, Marc Ychou, Brice Pastor, Feng Tian, Laura Henderson, Zhi-Qin Jiang, Ji Yuan Wu, Nila U. Parikh, Christine M. Parseghian
Lack of correlation between Src activity in PBMCs and hepatic tumors. For the patients in the expansion cohort, the change in the expression of pSrc and total Src was not correlated with a change in the phosphorlyation of the Src substrate paxillin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5672206e4a57e3878ce7df721ab8dd75
https://doi.org/10.1158/1078-0432.22468070
https://doi.org/10.1158/1078-0432.22468070
Autor:
Scott Kopetz, Gary E. Gallick, Alain R. Thierry, Michael J. Overman, Cathy Eng, Robert A. Wolff, David G. Menter, Anastasia D. Katsiampoura, David R. Fogelman, Arvind Dasari, Kanwal Raghav, Marc Ychou, Brice Pastor, Feng Tian, Laura Henderson, Zhi-Qin Jiang, Ji Yuan Wu, Nila U. Parikh, Christine M. Parseghian
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6de45cfc6edbbcea78b449ba18cb9e
https://doi.org/10.1158/1078-0432.22468067.v1
https://doi.org/10.1158/1078-0432.22468067.v1
Autor:
Scott Kopetz, Gary E. Gallick, Alain R. Thierry, Michael J. Overman, Cathy Eng, Robert A. Wolff, David G. Menter, Anastasia D. Katsiampoura, David R. Fogelman, Arvind Dasari, Kanwal Raghav, Marc Ychou, Brice Pastor, Feng Tian, Laura Henderson, Zhi-Qin Jiang, Ji Yuan Wu, Nila U. Parikh, Christine M. Parseghian
Prespecified dose modifications for adverse events related to study drug in Phase IB and Phase II.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e078b166a2a088e82f0ff7ed848b01
https://doi.org/10.1158/1078-0432.22468055
https://doi.org/10.1158/1078-0432.22468055
Autor:
Scott Kopetz, Marc Ychou, Safia El Messaoudi, Cynthia Sanchez, Michael J. Overman, Jonathan M. Loree, Christine Parseghian, Anastasia D. Katsiampoura, Zhi-Qin Jiang, Brice Pastor, Alain R. Thierry
Legend Supplemental Table S1 : Point mutations tested by plasma analysis in the KPLEX R study, (A). Comparison of point mutations tested by tumor tissue and plasma analysis, (B). Legend Supplemental Table S2: Concordance between tumor-tissue analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a5e3cea5f1d6ad51b68b222bedfb14
https://doi.org/10.1158/1078-0432.22462778
https://doi.org/10.1158/1078-0432.22462778