Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Anastasia Arvaniti"'
Autor:
Nantia Othonos, Riccardo Pofi, Anastasia Arvaniti, Sarah White, Ilaria Bonaventura, Nikolaos Nikolaou, Ahmad Moolla, Thomas Marjot, Roland H. Stimson, André P. van Beek, Martijn van Faassen, Andrea M. Isidori, Elizabeth Bateman, Ross Sadler, Fredrik Karpe, Paul M. Stewart, Craig Webster, Joanne Duffy, Richard Eastell, Fatma Gossiel, Thomas Cornfield, Leanne Hodson, K. Jane Escott, Andrew Whittaker, Ufuk Kirik, Ruth L. Coleman, Charles A. B. Scott, Joanne E. Milton, Olorunsola Agbaje, Rury R. Holman, Jeremy W. Tomlinson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Glucocorticoids prescribed to limit inflammation, have significant adverse effects. Here the authors show that co-administration of AZD4017 with prednisolone in men is a potential strategy to limit adverse glucocorticoid effects.
Externí odkaz:
https://doaj.org/article/d5729cc721e9453cb5043aab11c131a3
Autor:
Julia Ast, Anastasia Arvaniti, Nicholas H. F. Fine, Daniela Nasteska, Fiona B. Ashford, Zania Stamataki, Zsombor Koszegi, Andrea Bacon, Ben J. Jones, Maria A. Lucey, Shugo Sasaki, Daniel I. Brierley, Benoit Hastoy, Alejandra Tomas, Giuseppe D’Agostino, Frank Reimann, Francis C. Lynn, Christopher A. Reissaus, Amelia K. Linnemann, Elisa D’Este, Davide Calebiro, Stefan Trapp, Kai Johnsson, Tom Podewin, Johannes Broichhagen, David J. Hodson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Glucagon-like peptide-1 receptor is an important regulator of appetite and glucose homeostasis. Here the authors describe super-resolution microscopy and in vivo imaging compatible fluorescent probes, which reveal endogenous glucagon-like peptide-1 r
Externí odkaz:
https://doaj.org/article/1bec881e08194ff3b4ad84658e067529
Autor:
Oladapo E. Olaniru, Jordan Cheng, Julia Ast, Anastasia Arvaniti, Patricio Atanes, Guo C. Huang, Aileen J.F. King, Peter M. Jones, Johannes Broichhagen, David J. Hodson, Shanta J. Persaud
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101285- (2021)
Objective: Members of the adhesion G protein-coupled receptor (aGPCR) subfamily are important actors in metabolic processes, with GPR56 (ADGRG1) emerging as a possible target for type 2 diabetes therapy. GPR56 can be activated by collagen III, its en
Externí odkaz:
https://doaj.org/article/3df09aa019eb4776af546b1d54def1df
Autor:
Julia Ast, Anastasia Arvaniti, Nicholas H. F. Fine, Daniela Nasteska, Fiona B. Ashford, Zania Stamataki, Zsombor Koszegi, Andrea Bacon, Ben J. Jones, Maria A. Lucey, Shugo Sasaki, Daniel I. Brierley, Benoit Hastoy, Alejandra Tomas, Giuseppe D’Agostino, Frank Reimann, Francis C. Lynn, Christopher A. Reissaus, Amelia K. Linnemann, Elisa D’Este, Davide Calebiro, Stefan Trapp, Kai Johnsson, Tom Podewin, Johannes Broichhagen, David J. Hodson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/ec33e8108ee44445a3672afb9f0516cc
Autor:
Laura L Gathercole, Nikolaos Nikolaou, Shelley E Harris, Anastasia Arvaniti, Toryn M Poolman, Jonathan M Hazlehurst, Denise V Kratschmar, Marijana Todorčević, Ahmad Moolla, Niall Dempster, Ryan C Pink, Michael F Saikali, Liz Bentley, Trevor M Penning, Claes Ohlsson, Carolyn L Cummins, Matti Poutanen, Alex Odermatt, Roger D Cox, Jeremy W Tomlinson
Publikováno v:
Journal of Endocrinology. 253:97-113
Steroid 5β-reductase (AKR1D1) plays important role in hepatic bile acid synthesis and glucocorticoid clearance. Bile acids and glucocorticoids are potent metabolic regulators, but whether AKR1D1 controls metabolic phenotype in vivo is unknown. Akr1d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de9778b5b1fbb3dbdd7f97861c4fc255
https://doi.org/10.1530/joe-21-0280
https://doi.org/10.1530/joe-21-0280
Autor:
Nikolaos Nikolaou, Anastasia Arvaniti, Fabio Sanna, Conceicao Ismael da, Niall Dempster, Laura Gathercole, Jeremy Tomlinson
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7158925c1d29d40d2382f4f747f1a055
https://doi.org/10.1530/endoabs.86.oc5.2
https://doi.org/10.1530/endoabs.86.oc5.2
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::512c2194a72978afa9ac5d7248b6eda4
https://doi.org/10.1530/endoabs.86.p200
https://doi.org/10.1530/endoabs.86.p200
Autor:
Elena Gangitano, Trevor M. Penning, Sherly George, Nathan Appanna, Jeremy W. Tomlinson, Nikolaos Nikolaou, Laura Gathercole, Brian G. Keevil, Niall Dempster, Hylton Gibson, Karen Morris, Karl-Heinz Storbeck, Anastasia Arvaniti
Publikováno v:
Journal of Molecular Endocrinology
Steroid hormones, including glucocorticoids and androgens, exert a wide variety of effects in the body across almost all tissues. The steroid A-ring 5β-reductase (AKR1D1) is expressed in human liver and testes, and three splice variants have been id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107c6a5ec45b79e991b299269956371f
https://doi.org/10.1530/jme-20-0160
https://doi.org/10.1530/jme-20-0160
Autor:
Nikolaos Nikolaou, Anastasia Arvaniti, Fabio Sanna, Conceicao Ragazzon da, Niall Dempster, Laura Gathercole, Jeremy Tomlinson
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::459ff9fd87b461e29f55e5f94d67fc50
https://doi.org/10.1530/endoabs.81.yi8
https://doi.org/10.1530/endoabs.81.yi8
Autor:
Toryn Poolman, Anastasia Arvaniti, Laura Gathercole, Roger D. Cox, Shelley Harris, Jeremy W. Tomlinson
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
The pathogenesis of nonalcoholic fatty liver disease (NAFLD) and the progression to nonalcoholic steatohepatitis (NASH) and increased risk of hepatocellular carcinoma remain poorly understood. Additionally, there is increasing recognition of the extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc92abfe34688da9e265806c8757524
https://doi.org/10.1152/ajpgi.00055.2020
https://doi.org/10.1152/ajpgi.00055.2020