Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anas H. Awan"'
Autor:
Kellie N. Smith, Nicolas J. Llosa, Tricia R. Cottrell, Nicholas Siegel, Hongni Fan, Prerna Suri, Hok Yee Chan, Haidan Guo, Teniola Oke, Anas H. Awan, Franco Verde, Ludmila Danilova, Valsamo Anagnostou, Ada J. Tam, Brandon S. Luber, Bjarne R. Bartlett, Laveet K. Aulakh, John-William Sidhom, Qingfeng Zhu, Cynthia L. Sears, Leslie Cope, William H. Sharfman, Elizabeth D. Thompson, Joanne Riemer, Kristen A. Marrone, Jarushka Naidoo, Victor E. Velculescu, Patrick M. Forde, Bert Vogelstein, Kenneth W. Kinzler, Nickolas Papadopoulos, Jennifer N. Durham, Hao Wang, Dung T. Le, Sune Justesen, Janis M. Taube, Luis A. Diaz, Julie R. Brahmer, Drew M. Pardoll, Robert A. Anders, Franck Housseau
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-8 (2019)
Abstract Background Several predictive biomarkers are currently approved or are under investigation for the selection of patients for checkpoint blockade. Tumor PD-L1 expression is used for stratification of non-small cell lung (NSCLC) patients, with
Externí odkaz:
https://doaj.org/article/1bbf8602f6f8428183fdc7d49f984cca
Autor:
Kellie N. Smith, Nicolas J. Llosa, Tricia R. Cottrell, Nicholas Siegel, Hongni Fan, Prerna Suri, Hok Yee Chan, Haidan Guo, Teniola Oke, Anas H. Awan, Franco Verde, Ludmila Danilova, Valsamo Anagnostou, Ada J. Tam, Brandon S. Luber, Bjarne R. Bartlett, Laveet K. Aulakh, John-William Sidhom, Qingfeng Zhu, Cynthia L. Sears, Leslie Cope, William H. Sharfman, Elizabeth D. Thompson, Joanne Riemer, Kristen A. Marrone, Jarushka Naidoo, Victor E. Velculescu, Patrick M. Forde, Bert Vogelstein, Kenneth W. Kinzler, Nickolas Papadopoulos, Jennifer N. Durham, Hao Wang, Dung T. Le, Sune Justesen, Janis M. Taube, Luis A. Diaz Jr, Julie R. Brahmer, Drew M. Pardoll, Robert A. Anders, Franck Housseau
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-2 (2019)
Externí odkaz:
https://doaj.org/article/53de6d1b2ed144d48e2c742123df82a4
Data from Immunopathologic Stratification of Colorectal Cancer for Checkpoint Blockade Immunotherapy
Autor:
Robert A. Anders, Franck Housseau, Hao Wang, Drew M. Pardoll, Luis A. Diaz, Dung T. Le, Cynthia L. Sears, Jennifer N. Durham, Elizabeth M. Jaffee, Elizabeth D. Thompson, Laveet K. Aulakh, Bjarne R. Bartlett, Qingfeng Zhu, Teniola Oke, Anas H. Awan, Nicholas Siegel, Brandon Luber, Nicolas J. Llosa
Mismatch-repair deficiency in solid tumors predicts their response to PD-1 blockade. Based on this principle, pembrolizumab is approved as standard of care for patients with unresectable or metastatic microsatellite instability–high (MSI-H) cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26bd97c0a7493fb2d388f0fc44d9d416
https://doi.org/10.1158/2326-6066.c.6549880
https://doi.org/10.1158/2326-6066.c.6549880
Autor:
Robert A. Anders, Franck Housseau, Hao Wang, Drew M. Pardoll, Luis A. Diaz, Dung T. Le, Cynthia L. Sears, Jennifer N. Durham, Elizabeth M. Jaffee, Elizabeth D. Thompson, Laveet K. Aulakh, Bjarne R. Bartlett, Qingfeng Zhu, Teniola Oke, Anas H. Awan, Nicholas Siegel, Brandon Luber, Nicolas J. Llosa
Supplementary figures 1-6 and tables 1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5184152cc5bb8bc1915666672decd7
https://doi.org/10.1158/2326-6066.22542334
https://doi.org/10.1158/2326-6066.22542334
Autor:
Franck Housseau, Robert A. Anders, Hao Wang, Drew M. Pardoll, Luis A. Diaz, Dung T. Le, Cynthia L. Sears, Jennifer N. Durham, Janis M. Taube, Elizabeth D. Thompson, Laveet K. Aulakh, Bjarne R. Bartlett, Charles A. Roberts, Elizabeth L. Engle, Jada Domingue, JiaJia Zhang, Teniola Oke, Hongni Fan, Anas H. Awan, Nicholas Siegel, Kellie N. Smith, Ada J. Tam, Brandon Luber, Nicolas J. Llosa
supplementary methods, tables and figures Supplementary Table S1. Demographics of patients from clinical trial NCT01876511 Supplementary Table S2. Demographics of untreated CRC patients Supplementary Table S3. Target genes and specific primer/probes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef7e187522cc9c69f0662a6d78dc2aa
https://doi.org/10.1158/1078-0432.22475976.v1
https://doi.org/10.1158/1078-0432.22475976.v1
Autor:
Nooshin Mirkheshti, Eugene Shenderov, Mario A. Eisenberger, Michael A. Carducci, Pedro Isaacsson Velho, Tamara L. Lotan, Emmanuel S. Antonarakis, Hao Wang, Drew M. Pardoll, Anas H. Awan
Publikováno v:
The Prostate. 79:1572-1579
BACKGROUND: Isolated pulmonary involvement is uncommon in metastatic hormone-sensitive prostate cancer (mHSPC). To characterize outcomes and molecular alterations of this unique patient subset, we conducted a retrospective review of patients with hor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d653d79c7c9cefb55d5e884cb5d952
https://doi.org/10.1002/pros.23881
https://doi.org/10.1002/pros.23881
Autor:
Qingfeng Zhu, Haidan Guo, Franco Verde, Hao Wang, Patrick M. Forde, Dung T. Le, Sune Justesen, Teniola Oke, Hongni Fan, Prerna Suri, Leslie Cope, Ludmila Danilova, Janis M. Taube, Anas H. Awan, Franck Housseau, Jennifer N. Durham, Hok Yee Chan, Nickolas Papadopoulos, Elizabeth D. Thompson, Bjarne Bartlett, Robert A. Anders, Nicholas Siegel, Victor E. Velculescu, Kellie N. Smith, John-William Sidhom, Laveet K. Aulakh, Kristen A. Marrone, Valsamo Anagnostou, Cynthia L. Sears, Joanne Riemer, Drew M. Pardoll, Luis A. Diaz, Brandon Luber, Ada J. Tam, Bert Vogelstein, Tricia R. Cottrell, Nicolas J. Llosa, Kenneth W. Kinzler, Julie R. Brahmer, William H. Sharfman, Jarushka Naidoo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-8 (2019)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Background Several predictive biomarkers are currently approved or are under investigation for the selection of patients for checkpoint blockade. Tumor PD-L1 expression is used for stratification of non-small cell lung (NSCLC) patients, with tumor mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde77c99e032427f14a5fba99a381eba
http://link.springer.com/article/10.1186/s40425-018-0492-x
http://link.springer.com/article/10.1186/s40425-018-0492-x
Autor:
Dung T. Le, Teniola Oke, Janis M. Taube, Hongni Fan, Elizabeth D. Thompson, Laveet K. Aulakh, Charles Roberts, Jiajia Zhang, Brandon Luber, Kellie N. Smith, Bjarne Bartlett, Robert A. Anders, Anas H. Awan, Franck Housseau, Nicolas J. Llosa, Jennifer N. Durham, Nicholas Siegel, Hao Wang, Elizabeth L. Engle, Ada J. Tam, Drew M. Pardoll, Luis A. Diaz, Jada C. Domingue, Cynthia L. Sears
Publikováno v:
Clin Cancer Res
Purpose: Approximately 10% of patients with mismatch repair–proficient (MMRp) colorectal cancer showed clinical benefit to anti-PD-1 monotherapy (NCT01876511). We sought to identify biomarkers that delineate patients with immunoreactive colorectal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7834769adea7fa2755358a1f1e671e0
https://europepmc.org/articles/PMC6726531/
https://europepmc.org/articles/PMC6726531/
Autor:
Qingfeng Zhu, Elizabeth D. Thompson, Laveet K. Aulakh, Teniola Oke, Cynthia L. Sears, Dung T. Le, Robert A. Anders, Anas H. Awan, Elizabeth M. Jaffee, Franck Housseau, Jennifer N. Durham, Drew M. Pardoll, Luis A. Diaz, Hao Wang, Bjarne Bartlett, Nicholas Siegel, Nicolas J. Llosa, Brandon Luber
Publikováno v:
Cancer immunology research. 7(10)
Mismatch-repair deficiency in solid tumors predicts their response to PD-1 blockade. Based on this principle, pembrolizumab is approved as standard of care for patients with unresectable or metastatic microsatellite instability–high (MSI-H) cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6336f9420d93e585677a7d7236cbdbfc
https://pubmed.ncbi.nlm.nih.gov/31439614
https://pubmed.ncbi.nlm.nih.gov/31439614
Autor:
Qingfeng Zhu, Victor E. Velculescu, Bjarne Bartlett, Haidan Guo, Robert A. Anders, Drew M. Pardoll, Luis A. Diaz, William H. Sharfman, Brandon Luber, Prerna Suri, Nicholas Siegel, Valsamo Anagnostou, Sune Justesen, Patrick M. Forde, Hok Yee Chan, John-William Sidhom, Hao Wang, Franco Verde, Nickolas Papadopoulos, Dung T. Le, Teniola Oke, Bert Vogelstein, Elizabeth D. Thompson, Cynthia L. Sears, Hongni Fan, Tricia R. Cottrell, Kristen A. Marrone, Leslie Cope, Ada J. Tam, Ludmila Danilova, Anas H. Awan, Julie R. Brahmer, Jennifer N. Durham, Joanne Riemer, Jarushka Naidoo, Nicolas J. Llosa, Kenneth W. Kinzler, Janis M. Taube, Franck Housseau, Laveet K. Aulakh, Kellie N. Smith
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-2 (2019)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1ba002a5ad296dbfeabe7f34e14d3e
http://link.springer.com/article/10.1186/s40425-019-0547-7
http://link.springer.com/article/10.1186/s40425-019-0547-7