Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ananthi J. Asirvatham"'
Autor:
Thomas B. Tomasi, Ananthi J. Asirvatham, William J. Magner, Zihua Hu, Christopher J. Gregorie
Publikováno v:
Molecular Immunology. 45:1995-2006
We studied 613 genes which regulate immunity and, utilizing predictive algorithms, identified 285 genes as microRNA (miRNA or miR) targets. Of these, approximately 250 are newly predicted gene-miR interactions. The frequency of predicted miRNA bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70761b77e93acee427f7a7f17fbe25a6
https://doi.org/10.1016/j.molimm.2007.10.035
https://doi.org/10.1016/j.molimm.2007.10.035
Publikováno v:
The Prostate. 67:1411-1420
Background The inhibitor of differentiation (Id) proteins are expressed in prostate cancer (PCA). However, there is a general lack of Id isoform-specific downstream effectors. Methods Id1, Id2, or Id3 were silenced in PCA cell lines LNCaP, DU145, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89996421ee6c1c82b6e2927a8a4b1c74
https://doi.org/10.1002/pros.20633
https://doi.org/10.1002/pros.20633
Publikováno v:
The Prostate. 66:921-935
BACKGROUND The four Id (inhibitor of differentiation) proteins (Id1, Id2, Id3, and Id4) dimerize and neutralize the transcriptional activity of basic helix-loop-helix (bHLH) proteins. The Id proteins negatively regulate differentiation and promote pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80bc4a94ada6eeacb30c518523506a1
https://doi.org/10.1002/pros.20366
https://doi.org/10.1002/pros.20366
Publikováno v:
Endocrinology. 147:257-271
A major hurdle in understanding the role of androgens is the heterogeneity of androgen receptor (AR) expression in the prostate. Because the majority of prostate cancer arises from the AR-positive secretory luminal epithelial cells, identifying the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93aa53d1db6ba87fe4dbb6cbe1c09c32
https://doi.org/10.1210/en.2005-0942
https://doi.org/10.1210/en.2005-0942
Autor:
Anthony N. Imbalzano, Ananthi J. Asirvatham, Nathalie Cohet, Valerie M. Weaver, Jeffrey A. Nickerson, Rajini Mudhasani, Kathleen M. Stewart, Karen M. Imbalzano, Chandrashekara Mallappa
Publikováno v:
Journal of cellular physiology. 223(3)
The ATPase subunits of the SWI/SNF chromatin remodeling enzymes, Brahma (BRM) and Brahma related gene 1 (BRG1), can induce cell cycle arrest in BRM and BRG1 deficient tumor cell lines, and mice heterozygous for Brg1 are predisposed to breast tumors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501e2736912a5874b7eac534b5e0f33c
https://pubmed.ncbi.nlm.nih.gov/20333683
https://pubmed.ncbi.nlm.nih.gov/20333683
Publikováno v:
Cellular & Molecular Biology Letters
Id1 (inhibitor of differentiation 1) is a member of the bHLH protein family. Consistent with its role in promoting proliferation and inhibiting differentiation, Id1 expression is low or negligible in normal prostate epithelial cells but is high in pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45abdd7cb9e14d1647f836baecbe2cf5
https://doi.org/10.2478/s11658-010-0007-3
https://doi.org/10.2478/s11658-010-0007-3
Publikováno v:
Cytokine. 45(2)
In this review we discuss specific examples of regulation of cytokine genes and focus on a new mechanism involving post-transcriptional regulation via miRNAs. The post-transcriptional regulation of cytokine genes via the destabilizing activity of AU-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272cbde3a95b699a9edd21fb55c4e2e2
https://pubmed.ncbi.nlm.nih.gov/19121586
https://pubmed.ncbi.nlm.nih.gov/19121586
Publikováno v:
BMC Cancer
BMC Cancer, Vol 9, Iss 1, p 173 (2009)
BMC Cancer, Vol 9, Iss 1, p 173 (2009)
Background Inhibitor of differentiation 4 (Id4), a member of the Id gene family is also a dominant negative regulator of basic helix loop helix (bHLH) transcription factors. Some of the functions of Id4 appear to be unique as compared to its other fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574c32b21b40728aa85a02308b521072