Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ananthachari Srinivasan"'
Autor:
John M. Reno, Lori J. Hobson, Donald B. Axworthy, Paul L. Beaumier, Tripuraneni N. Rao, Alan R. Fritzberg, Ananthachari Srinivasan, James Sanderson, Jeffrey N. Fitzner, Sudhakar Kasina
Publikováno v:
Bioconjugate Chemistry. 9:108-117
A simplified kiet has been developed for 99mTc protein radiolabeling using an N3S triamide mercaptide bifunctional chelating agent and the preformed chelate approach. The process combined N3S chelating agent, gluconate intermediate transfer agent, st
Publikováno v:
ChemInform. 22
This communication describes a convenient, two step procedure for the preparation of S-benzyl-d,1-isocysteine from mercaptosuccinic acid in 49% yield.
Publikováno v:
ChemInform. 22
Sulfur protected mercaptosuccinic acid β-monoesters were prepared by two complimentary methods. Alkylation of enolates of hemithioacetal protected mercaptoacetic acid with t-butyl bromoacetate directly provides the base stable t-butyl esters 2a and
Autor:
Linda M. Gustavson, Ananthachari Srinivasan, Alan R. Fritzberg, Tripuraneni N. Rao, Sudhakar Kasina
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. 19:889-895
The exchange reactions of S-protected dithiol monoaminemonoamide (MAMA) ligands with Tc(V)-gluconate were investigated. Protection of the mercaptide sulfur atoms with acid, base and metal labile groups permitted complex formation of the MAMA ligands
Autor:
Ananthachari Srinivasan, Linda M. Gustavson, Tripuraneni N. Rao, David S. Jones, Alan R. Fritzberg
Publikováno v:
Tetrahedron Letters. 32:5485-5488
A novel N2S2-monoamine amide (MAMA) bifunctional chelate was designed and synthesized for labeling of antibodies with Tc-99m. The chelate forms Tc complexes at a range of pH's and shows faster kinetics of complexation than N2S2-diamidedithiol (DADS)
Publikováno v:
Synthetic Communications. 21:265-270
This communication describes a convenient, two step procedure for the preparation of S-benzyl-d,1-isocysteine from mercaptosuccinic acid in 49% yield.
Publikováno v:
Synthetic Communications. 21:249-263
Sulfur protected mercaptosuccinic acid β-monoesters were prepared by two complimentary methods. Alkylation of enolates of hemithioacetal protected mercaptoacetic acid with t-butyl bromoacetate directly provides the base stable t-butyl esters 2a and
Autor:
Jack L. Erion, B. Waser, Eric P. Krenning, H. F. Bernard, M. de Jong, Michelle A. Schmidt, Ananthachari Srinivasan, M. de Visser, Jean Claude Reubi
Publikováno v:
de Visser, M; Bernard, H F; Erion, J L; Schmidt, M A; Srinivasan, A; Waser, B; Reubi, J. C.; Krenning, E P; de Jong, M (2007). Novel 111In-labelled bombesin analogues for molecular imaging of prostate tumours. European journal of nuclear medicine and molecular imaging, 34(8), pp. 1228-38. Berlin: Springer 10.1007/s00259-006-0356-3
European Journal of Nuclear Medicine and Molecular Imaging, 34(8), 1228-1238. Springer-Verlag
European Journal of Nuclear Medicine and Molecular Imaging, 34(8), 1228-1238. Springer-Verlag
PURPOSE: It has been shown that some primary human tumours and their metastases, including prostate and breast tumours, overexpress gastrin-releasing peptide (GRP) receptors. Bombesin (BN) is a neuropeptide with a high affinity for these GRP receptor
Autor:
E. P. Krenning, Jean Claude Reubi, Jack L. Erion, M. de Jong, Michelle A. Schmidt, Ananthachari Srinivasan, M. de Visser, Paul J. J. M. Janssen, B. Waser
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging, 30(8), 1134-1139. Springer-Verlag
Neurotensin (NT) receptors are overexpressed in exocrine pancreatic cancer and Ewing's sarcoma. The potential utility of native NT in cancer diagnosis and therapy is, however, limited by its rapid degradation in vivo. Therefore, NT analogues were syn
Autor:
Jack L. Erion, J. E. Bugaj, B. Waser, U. Laederach, Jean-Claude Schaer, Ananthachari Srinivasan, Jean Claude Reubi, Michelle A. Schmidt
Publikováno v:
European journal of nuclear medicine. 25(5)
Receptors for regulatory peptides such as somatostatin or vasoactive intestinal polypeptide are expressed by a number of human neoplasms and can be visualized in vivo with peptide receptor scintigraphy. Recently, the CCK-B receptor, which binds both