Connecting moss lipid droplets to patchoulol biosynthesis

Autor: Anantha Vithakshana Peramuna, Arvid Fromberg, Bent O. Petersen, Henrik Toft Simonsen, Carmen Quiñonero López, Hansol Bae

Publikováno v: Peramuna, A, Bae, H, Quiñonero López, C, Fromberg, A, Petersen, B & Simonsen, H T 2020, ' Connecting moss lipid droplets to patchoulol biosynthesis ', PLoS ONE, vol. 15, no. 12, e0243620 . https://doi.org/10.1371/journal.pone.0243620
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0243620 (2020)
Vithakshana Peramuna, A, Bae, H, Quiñonero López, C, Fromberg, A, Petersen, B & Simonsen, H T 2020, ' Connecting moss lipid droplets to patchoulol biosynthesis ', PLOS ONE, vol. 15, no. 12, e0243620 . https://doi.org/10.1371/journal.pone.0243620

Plant-derived terpenoids are extensively used in perfume, food, cosmetic and pharmaceutical industries, and several attempts are being made to produce terpenes in heterologous hosts. Native hosts have evolved to accumulate large quantities of terpene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43db452c4acdc77f94baa403135653c4
https://curis.ku.dk/portal/da/publications/connecting-moss-lipid-droplets-to-patchoulol-biosynthesis(2e7f6003-5bb5-441b-83d6-7f3fabe30069).html

Production of terpenes and terpenoids

Autor: Henrik Toft Simonsen, Anantha Vithakshana Peramuna

Publikováno v: Simonsen, H T & Peramuna, A V Sep. 21 2018, Production of terpenes and terpenoids, Patent No. WO2019057258, IPC No. A01H 11/ 00 A N .
Technical University of Denmark Orbit

This invention relates to a transgenic bryophytic cell capable of producing geranyl pyrophosphate (GPP), farnesyl-pyrophosphate (FPP) and/or geranylgeranyl pyrophosphate (GGPP) comprising at least one heterologous nucleic acid molecule encoding at le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b5a62d727bf2567de10017a36dd0b269
https://orbit.dtu.dk/ws/files/191910700/WO2019057258A1.pdf

Evaluation of synthetic promoters in Physcomitrella patens

Autor: Henrik Toft Simonsen, Anantha Vithakshana Peramuna, Erling Koch Rasmussen, Bjørn Dueholm, Hansol Bae, Brzezek Kerstin, Michael M. Roberts, Joanna H. Critchley, Thomas Waibel

Publikováno v: Peramuna, A, Bae, H, Rasmussen, E K, Dueholm, B, Waibel, T, Critchley, J H, Brzezek, K, Roberts, M & Simonsen, H T 2018, ' Evaluation of synthetic promoters in Physcomitrella patens ', Biochemical and Biophysical Research Communications, vol. 500, no. 2, pp. 418-422 . https://doi.org/10.1016/j.bbrc.2018.04.092

Securing a molecular toolbox including diverse promoters is essential for genome engineering. However, native promoters have limitations such as the available number or the length of the promoter. In this work, three short synthetic promoters were ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8673b3999f67cc5a06e8073543326f4f
https://pubmed.ncbi.nlm.nih.gov/29660341

Stable Production of the Antimalarial Drug Artemisinin in the Moss Physcomitrella patens

Autor: Anantha Vithakshana Peramuna, Alexander R. van der Krol, Arman Beyraghdar Kashkooli, Harro J. Bouwmeester, Nur Kusaira Khairul Ikram, Henrik Toft Simonsen

Publikováno v: Frontiers in Bioengineering and Biotechnology 5 (2017)
Binti Khairul Ikram, N K, Kashkooli, A B, Peramuna, A V, van der Krol, A R, Bouwmeester, H & Simonsen, H T 2017, ' Stable production of the antimalarial drug artemisinin in the moss Physcomitrella patens ', Frontiers in Bioengineering and Biotechnology, vol. 5, no. 47 . https://doi.org/10.3389/fbioe.2017.00047
Khairul Ikram, N K B, Beyraghdar Kashkooli, A, Peramuna, A V, van der Krol, A R, Bouwmeester, H & Simonsen, H T 2017, ' Stable Production of the Antimalarial Drug Artemisinin in the Moss Physcomitrella patens ', Frontiers in Bioengineering and Biotechnology, vol. 5, 47 . https://doi.org/10.3389/fbioe.2017.00047
Frontiers in Bioengineering and Biotechnology, 5
Frontiers in Bioengineering and Biotechnology, Vol 5 (2017)
Frontiers in Bioengineering and Biotechnology, 5:47. Frontiers Research Foundation
Frontiers in Bioengineering and Biotechnology

Malaria is a real and constant danger to nearly half of the world’s population of 7.4 billion people. In 2015, 212 million cases were reported along with 429,000 estimated deaths. The World Health Organization recommends artemisinin-based combinato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4267ee12479ea5cd66035dceed75fb68
https://research.wur.nl/en/publications/stable-production-of-the-antimalarial-drug-artemisinin-in-the-mos