Zobrazeno 1 - 10
of 569
pro vyhledávání: '"Ananth K"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Preterm birth rates and maternal and neonatal mortality remain concerning global health issues, necessitating improved strategies for testing therapeutic compounds during pregnancy. Current 2D or 3D cell models and animal models often f
Externí odkaz:
https://doaj.org/article/31e0bc1b54344874854f1e6c97a1f68f
Autor:
David C. Lauzier, Anna L. Huguenard, Anja I. Srienc, Samuel J. Cler, Joshua W. Osbun, Arindam R. Chatterjee, Ananth K. Vellimana, Akash P. Kansagra, Colin P. Derdeyn, Dewitte T. Cross, Christopher J. Moran
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Tools and techniques utilized in endovascular brain aneurysm treatment have undergone rapid evolution in recent decades. These technique and device-level innovations have allowed for treatment of highly complex intracranial aneurysms and improved pat
Externí odkaz:
https://doaj.org/article/90a0deeb834441499af571708c2337e2
Autor:
Meizi Liu, Keshav Jayaraman, James W. Nelson, Jogender Mehla, Deepti Diwan, Ananth K. Vellimana, Gregory J. Zipfel, Umeshkumar Athiraman
Publikováno v:
Diseases, Vol 11, Iss 4, p 130 (2023)
Delayed cerebral ischemia (DCI) is an important contributor to poor outcomes in aneurysmal subarachnoid hemorrhage (SAH) patients. We previously showed that volatile anesthetics such as isoflurane, sevoflurane and desflurane provided robust protectio
Externí odkaz:
https://doaj.org/article/703fc95edf794188ab4d41cff5f09f5f
Autor:
Meizi Liu, Keshav Jayaraman, Jogender Mehla, Deepti Diwan, James W. Nelson, Ahmed E. Hussein, Ananth K. Vellimana, Yousef Abu-Amer, Gregory J. Zipfel, Umeshkumar Athiraman
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1163 (2023)
Delayed cerebral ischemia (DCI) is the largest treatable cause of poor outcome after aneurysmal subarachnoid hemorrhage (SAH). Nuclear Factor Kappa-light-chain-enhancer of Activated B cells (NF-kB), a transcription factor known to function as a pivot
Externí odkaz:
https://doaj.org/article/de7776b9f2a049e9baab28b686714910
Autor:
Hariharan Subramanian, Tanwir Hashem, Devika Bahal, Ananth K. Kammala, Kanedra Thaxton, Rupali Das
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Asthma prevalence has increased considerably over the decades and it is now considered as one of the most common chronic disorders in the world. While the current anti-asthmatic therapies are effective for most asthma patients, there are 5-10% subjec
Externí odkaz:
https://doaj.org/article/a2bcef97ba474193aff4479f7b8ad153
Publikováno v:
Frontiers in Allergy, Vol 2 (2021)
G protein-coupled receptor kinase 2 (GRK2) is an adapter protein that modulates G protein-coupled receptor (GPCR) signaling. It also regulates the functions and activity of other intracellular proteins in many cell types. Accordingly, GRK2 is thought
Externí odkaz:
https://doaj.org/article/893dd2953ffc488b84a4779978d91562
Autor:
Tanwir Hashem, Ananth K. Kammala, Kanedra Thaxton, Ryan M. Griffin, Kellie Mullany, Reynold A. Panettieri, Hariharan Subramanian, Rupali Das
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Characteristic of allergic asthma, CD4+Th2 lymphocytes secrete Th2 cytokines, interleukin (IL)-4, IL-13, and IL-5 that mediate the inflammatory immune response. Surface expression of CD2 and its ligand, CD58, is increased on the monocytes and eosinop
Externí odkaz:
https://doaj.org/article/63d44d736e6740deae3394726fdde7bc
Autor:
Brianna N. Callahan, Ananth K. Kammala, Meesum Syed, Canchai Yang, Christopher J. Occhiuto, Rithvik Nellutla, Alena P. Chumanevich, Carole A. Oskeritzian, Rupali Das, Hariharan Subramanian
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Mast cells are tissue-resident innate immune cells known for their prominent role in mediating allergic reactions. MAS-related G-protein coupled receptor-X2 (MRGPRX2) is a promiscuous G-protein coupled receptor (GPCR) expressed on mast cells that is
Externí odkaz:
https://doaj.org/article/2d9b0fbc80cd47fbafbd6ce2470522d9
Autor:
Christopher J. Occhiuto, Ananth K. Kammala, Canchai Yang, Rithvik Nellutla, Marco Garcia, Gregorio Gomez, Hariharan Subramanian
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Mast cells are inflammatory immune cells that play an essential role in mediating allergic reactions in humans. It is well-known that mast cell activation is critically regulated by intracellular calcium ion (Ca2+) concentrations. MAS-related G-prote
Externí odkaz:
https://doaj.org/article/91aed27a0f954efbbdcdae842c55d697
Autor:
Diane J. Aum, Ananth K. Vellimana, Itender Singh, Eric Milner, James W. Nelson, Byung Hee Han, Gregory J. Zipfel
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Various techniques have been developed to study changes in the cerebral vasculature in numerous neuropathological processes including subarachnoid hemorrhage (SAH). One of the most widely employed techniques uses India ink-gelatin casting, w
Externí odkaz:
https://doaj.org/article/59b09322c90344f5b94a3ad3adf684d8