Výsledky vyhledávání - "Ananth Chandrasekaran"

Identification and characterization of novel mouse PDE4D isoforms: Molecular cloning, subcellular distribution and detection of isoform-specific intracellular localization signals

Autor: Sydney Brenner, Stacey K.H. Tay, Kai Yee Toh, Ananth Chandrasekaran, Sean Haoquan Low, Denise L.M. Goh

Publikováno v: Cellular Signalling. 20:139-153

We report here the cloning and characterization of short and supershort mouse PDE4D isoforms. PDE4D is one of the phosphodiesterase enzyme families with multiple promoters and splice variants. PDE4 isoforms present in humans, rats and mice share cons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73701af67b84bc9739203501e409f06d
https://doi.org/10.1016/j.cellsig.2007.10.003

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SARS coronavirus nucleocapsid immunodominant T-cell epitope cluster is common to both exogenous recombinant and endogenous DNA-encoded immunogens

Autor: Thomas August, Kun Yang, Kai Sun, Tani M. Tabiin, Srinivasan N. Kellathur, Priya R. Chikhlikar, Ernesto T. A. Marques, Vandana Gupta, Ananth Chandrasekaran, Jerome Salmon, Vladimir Brusic, Azlinda Anwar

Publikováno v: Virology

Correspondence between the T-cell epitope responses of vaccine immunogens and those of pathogen antigens is critical to vaccine efficacy. In the present study, we analyzed the spectrum of immune responses of mice to three different forms of the SARS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0205fb94b03b0caa1a8c35e4c36d0df8
https://doi.org/10.1016/j.virol.2005.11.042

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Domoic acid-induced neurotoxicity in the hippocampus of adult rats

Autor: Charanjit Kaur, Ananth Chandrasekaran, Gopalakrishnakone Ponnambalam

Publikováno v: Neurotoxicity Research. 6:105-117

Domoic acid (DA), an agonist of non-N-methyl-D-aspartate (non-NMDA) receptor subtype including kainate receptor, was identified as a potent neurotoxin showing involvement in neuropathological processes like neuronal degeneration and atrophy. In the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfff0dc7b5eaa9a881f5c1729f9f573c
https://doi.org/10.1007/bf03033213

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West Nile premembrane-envelope genetic vaccine encoded as a chimera containing the transmembrane and cytoplasmic domains of a lysosome-associated membrane protein: increased cellular concentration of the transgene product, targeting to the MHC II compartment, and enhanced neutralizing antibody response

Autor: Mah Lee Ng, Ernesto T. A. Marques, J. Thomas August, Azlinda Anwar, Ananth Chandrasekaran

Publikováno v: Virology. 332(1)

A genetic vaccine for West Nile virus (WN) has been synthesized with the WN premembrane-envelope (WN preM-E) gene sequences encoded as a chimera with the transmembrane and carboxyl terminal domains of the lysosome-associated membrane protein (LAMP).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d230a9fc3d1298aabc44e3b3a880310
https://pubmed.ncbi.nlm.nih.gov/15661141

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