Synthesis, preclinical, and initial clinical evaluation of integrin α V β 3 and gastrin-releasing peptide receptor (GRPR) dual-targeting radiotracer [ ⁶⁸ Ga]Ga-RGD-RM26-03.

Autor: Wen X; State Key Laboratory of Molecular Vaccinology and Molecular, Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, 4221-116 Xiang'An South Rd, Xiamen, 361102, China., Wang R; Department of Nuclear Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100730, China., Xu P; Department of Nuclear Medicine, The First Affiliated Hospital of Weifang Medical University, Weifang, China., Shi M; Department of Diagnostic Radiology, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore, 119074, Singapore.; Nanomedicine Translational Research Program, NUS Center for Nanomedicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore., Shang Q; Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China., Zeng X; State Key Laboratory of Molecular Vaccinology and Molecular, Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, 4221-116 Xiang'An South Rd, Xiamen, 361102, China., Zeng X; State Key Laboratory of Molecular Vaccinology and Molecular, Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, 4221-116 Xiang'An South Rd, Xiamen, 361102, China., Liu J; State Key Laboratory of Molecular Vaccinology and Molecular, Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, 4221-116 Xiang'An South Rd, Xiamen, 361102, China., Wang X; Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China., Zhu Z; Department of Nuclear Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100730, China., Guo Z; State Key Laboratory of Molecular Vaccinology and Molecular, Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, 4221-116 Xiang'An South Rd, Xiamen, 361102, China., Chen X; Department of Diagnostic Radiology, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore, 119074, Singapore. chen.shawn@nus.edu.sg.; Nanomedicine Translational Research Program, NUS Center for Nanomedicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore. chen.shawn@nus.edu.sg.; Clinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore. chen.shawn@nus.edu.sg.; Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore. chen.shawn@nus.edu.sg.; Departments of Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore, 119074, Singapore. chen.shawn@nus.edu.sg., Zhang J; Department of Diagnostic Radiology, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore, 119074, Singapore. j.zhang@nus.edu.sg.; Nanomedicine Translational Research Program, NUS Center for Nanomedicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore. j.zhang@nus.edu.sg.; Clinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore. j.zhang@nus.edu.sg.

Publikováno v: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2024 Jun; Vol. 51 (7), pp. 2023-2035. Date of Electronic Publication: 2024 Feb 20.

GRPR-selective PET imaging of prostate cancer using [(18)F]-lanthionine-bombesin analogs.

Autor: Carlucci G; Department of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Kuipers A; Lanthio Pharma, Groningen, The Netherlands., Ananias HJ; Department of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., de Paula Faria D; Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Dierckx RA; Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Helfrich W; Surgical Research Laboratory, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Rink R; Lanthio Pharma, Groningen, The Netherlands., Moll GN; Lanthio Pharma, Groningen, The Netherlands; Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands., de Jong IJ; Department of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Elsinga PH; Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address: p.h.elsinga@umcg.nl.

Publikováno v: Peptides [Peptides] 2015 May; Vol. 67, pp. 45-54. Date of Electronic Publication: 2015 Mar 20.

Priapism following continuous thoracic epidural anaesthesia: emergency or a benign condition?

Autor: Fransen van de Putte EE; Department of Urology, Martini Hospital, Groningen, The Netherlands., Ananias HJ, Gi NP, de Boer HD

Publikováno v: Acta anaesthesiologica Scandinavica [Acta Anaesthesiol Scand] 2014 Aug; Vol. 58 (7), pp. 903-5. Date of Electronic Publication: 2014 Mar 28.

PSMA, EpCAM, VEGF and GRPR as imaging targets in locally recurrent prostate cancer after radiotherapy.

Autor: Rybalov M; Department of Urology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, Groningen 9700 RB NL, The Netherlands. maxrybalov@mail.ru., Ananias HJ; Department of Urology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, Groningen 9700 RB NL, The Netherlands. h.j.k.ananias@umcg.nl., Hoving HD; Department of Urology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, Groningen 9700 RB NL, The Netherlands. h.d.hoving@umcg.nl., van der Poel HG; Department of Urology, the Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands. h.vd.poel@nki.nl., Rosati S; Department of Pathology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, Groningen 9700 RB NL, The Netherlands. s.rosati@umcg.nl., de Jong IJ; Department of Urology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, Groningen 9700 RB NL, The Netherlands. i.j.de.jong@umcg.nl.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2014 Apr 10; Vol. 15 (4), pp. 6046-61. Date of Electronic Publication: 2014 Apr 10.

Application of (99m)Technetium-HYNIC(tricine/TPPTS)-Aca-Bombesin(7-14) SPECT/CT in prostate cancer patients: a first-in-man study.

Autor: Ananias HJ; Department of Urology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address: h.j.k.ananias@umcg.nl., Yu Z, Hoving HD, Rosati S, Dierckx RA, Wang F, Yan Y, Chen X, Pruim J, Lub-de Hooge MN, Helfrich W, Elsinga PH, de Jong IJ

Publikováno v: Nuclear medicine and biology [Nucl Med Biol] 2013 Oct; Vol. 40 (7), pp. 933-8. Date of Electronic Publication: 2013 Jul 26.