Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Anandwardhan A Hardikar"'
Autor:
Sahar I. Da’as, Ikhlak Ahmed, Waseem H. Hasan, Doua A. Abdelrahman, Elbay Aliyev, Sabah Nisar, Ajaz Ahmad Bhat, Mugdha V. Joglekar, Anandwardhan A. Hardikar, Khalid A. Fakhro, Ammira S. Al-Shabeeb Akil
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Type 2 diabetes (T2D) is a critical healthcare challenge and priority in Qatar which is listed amongst the top 10 countries in the world, with its prevalence presently at 17% double the global average. MicroRNAs (miRNAs) are impli
Externí odkaz:
https://doaj.org/article/afaa747b6ead43949eadded2d739a741
Autor:
Kwun Kiu Wong, Feifei Cheng, Cadmon K. P. Lim, Claudia H. T. Tam, Greg Tutino, Lai Yuk Yuen, Chi Chiu Wang, Yong Hou, Michael H. M. Chan, Chung Shun Ho, Mugdha V. Joglekar, Anandwardhan A. Hardikar, Alicia J. Jenkins, Boyd E. Metzger, William L. Lowe, Wing Hung Tam, Ronald C. W. Ma
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Leukocyte telomere length (LTL) is suggested to be a biomarker of biological age and reported to be associated with metabolic diseases such as type 2 diabetes. Glucose metabolic traits including glucose and insulin levels have bee
Externí odkaz:
https://doaj.org/article/b98d477d5d314a0f942fadeea67d4b18
Autor:
Ehsan Alvandi, Wilson K. M. Wong, Mugdha V. Joglekar, Kevin J. Spring, Anandwardhan A. Hardikar
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background The beneficial role of gut microbiota and bacterial metabolites, including short-chain fatty acids (SCFAs), is well recognized, although the available literature around their role in colorectal cancer (CRC) has been inconsistent.
Externí odkaz:
https://doaj.org/article/8be7df3df1834dacb69f67fd96307822
Autor:
Fathima Shihana, Mugdha V. Joglekar, Tae-Hwi Schwantes-An, Anandwardhan A. Hardikar, Devanshi Seth
Publikováno v:
Biology, Vol 12, Iss 10, p 1314 (2023)
Background: Alcohol-associated liver disease (ALD) is the most common disorder of prolonged drinking. Mechanisms underlying cirrhosis in such patients remain unclear. MicroRNAs play regulatory role in several diseases, are affected by alcohol and may
Externí odkaz:
https://doaj.org/article/df1327ce9050499ea74319c3265e0168
Autor:
Emma S. Scott, Andrzej S. Januszewski, Luke M. Carroll, Gregory R. Fulcher, Mugdha V. Joglekar, Anandwardhan A. Hardikar, Timothy W. Jones, Elizabeth A. Davis, Alicia J. Jenkins
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-4 (2021)
Abstract To determine whether continuous subcutaneous insulin infusion (CSII) vs. multiple daily injections (MDI) therapy from near-diagnosis of type 1 diabetes is associated with reduced glycaemic variability (GV) and altered microRNA (miRNAs) expre
Externí odkaz:
https://doaj.org/article/0adc48526a5746a2a86954d1d120e739
Autor:
Andrzej S. Januszewski, Yoon Hi Cho, Mugdha V. Joglekar, Ryan J. Farr, Emma S. Scott, Wilson K. M. Wong, Luke M. Carroll, Yik W. Loh, Paul Z. Benitez-Aguirre, Anthony C. Keech, David N. O’Neal, Maria E. Craig, Anandwardhan A. Hardikar, Kim C. Donaghue, Alicia J. Jenkins
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The aim of this cross-sectional study was to compare plasma C-peptide presence and levels in people without diabetes (CON) and with Type 1 diabetes and relate C-peptide status to clinical factors. In a subset we evaluated 50 microRNAs (miRs)
Externí odkaz:
https://doaj.org/article/b1ec56fdb12a4c0cb5cb32be78d2f006
Autor:
Fathima Shihana, Wilson K. M. Wong, Mugdha V. Joglekar, Fahim Mohamed, Indika B. Gawarammana, Geoffrey K. Isbister, Anandwardhan A. Hardikar, Devanshi Seth, Nicholas A. Buckley
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract MicroRNAs in biofluids are potential biomarkers for detecting kidney and other organ injuries. We profiled microRNAs in urine samples from patients with Russell’s viper envenoming or acute self-poisoning following paraquat, glyphosate, or
Externí odkaz:
https://doaj.org/article/ceee17a02abe49339b2390610baa4e8d
Autor:
Wilson K. M. Wong, Vinod Thorat, Mugdha V. Joglekar, Charlotte X. Dong, Hugo Lee, Yi Vee Chew, Adwait Bhave, Wayne J. Hawthorne, Feyza Engin, Aniruddha Pant, Louise T. Dalgaard, Sharda Bapat, Anandwardhan A. Hardikar
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Machine learning (ML)-workflows enable unprejudiced/robust evaluation of complex datasets. Here, we analyzed over 490,000,000 data points to compare 10 different ML-workflows in a large (N=11,652) training dataset of human pancreatic single-cell (sc-
Externí odkaz:
https://doaj.org/article/4c6b7c34dcfa4335982bc4796e302990
Autor:
Sandy R Shultz, Caroline J Taylor, Riemke Aggio-Bruce, William T O’Brien, Mujun Sun, Adrian V Cioanca, George Neocleous, Georgia F Symons, Rhys D Brady, Anandwardhan A Hardikar, Mugdha V Joglekar, Daniel M Costello, Terence J O’Brien, Riccardo Natoli, Stuart J McDonald
Publikováno v:
Biomarker Insights, Vol 17 (2022)
Introduction: Sports-related concussion (SRC) is a common form of brain injury that lacks reliable methods to guide clinical decisions. MicroRNAs (miRNAs) can influence biological processes involved in SRC, and measurement of miRNAs in biological flu
Externí odkaz:
https://doaj.org/article/6e5d1e47e8f3487faaf1d38c5e9fd355
Autor:
Mugdha V. Joglekar, Subhshri Sahu, Wilson K.M. Wong, Sarang N. Satoor, Charlotte X. Dong, Ryan J. Farr, Michael D. Williams, Prapti Pandya, Gaurang Jhala, Sundy N.Y. Yang, Yi Vee Chew, Nicola Hetherington, Dhan Thiruchevlam, Sasikala Mitnala, Guduru V. Rao, Duvvuru Nageshwar Reddy, Thomas Loudovaris, Wayne J. Hawthorne, Andrew G. Elefanty, Vinay M. Joglekar, Edouard G. Stanley, David Martin, Helen E. Thomas, David Tosh, Louise T. Dalgaard, Anandwardhan A. Hardikar
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 5, Pp 1530-1553.e4 (2022)
Background & Aims: Pancreatic islet β-cells are factories for insulin production; however, ectopic expression of insulin also is well recognized. The gallbladder is a next-door neighbor to the developing pancreas. Here, we wanted to understand if ga
Externí odkaz:
https://doaj.org/article/3d728a223a8941f1b6deb7467c5a4e8a