Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Anandi Krishnan"'
Autor:
Armi M. Chaudhari, Madhvi Joshi, Dinesh Kumar, Amrutlal Patel, Kiran Bharat Lokhande, Anandi Krishnan, Katja Hanack, Slawomir Filipek, Dorian Liepmann, Venkatesan Renugopalakrishnan, Ramasamy Paulmurugan, Chaitanya Joshi
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 4501-4516 (2022)
Emerging SARS-CoV-2 variants with higher transmissibility and immune escape remain a persistent threat across the globe. This is evident from the recent outbreaks of the Delta (B.1.617.2) and Omicron variants. These variants have originated from diff
Externí odkaz:
https://doaj.org/article/a34c1a6cb2df4f79933af63379748cee
Autor:
Robert A. Campbell, Bhanu Kanth Manne, Meenakshi Banerjee, Elizabeth A. Middleton, Abigail Ajanel, Hansjorg Schwertz, Frederik Denorme, Chris Stubben, Emilie Montenont, Samantha Saperstein, Lauren Page, Neal D. Tolley, Diana L. Lim, Samuel M. Brown, Colin K. Grissom, Douglas W. Sborov, Anandi Krishnan, Matthew T. Rondina
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 23 (2022)
Platelets and megakaryocytes are critical players in immune responses. Recent reports suggest infection and inflammation alter the megakaryocyte and platelet transcriptome to induce altered platelet reactivity. We determined whether nonviral sepsis i
Externí odkaz:
https://doaj.org/article/e7cbbd51329f4220a8154731cd4de615
Autor:
Zhu Shen, Wenfei Du, Cecelia Perkins, Lenn Fechter, Vanita Natu, Holden Maecker, Jesse Rowley, Jason Gotlib, James Zehnder, Anandi Krishnan
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100425- (2021)
Summary: Predicting disease progression remains a particularly challenging endeavor in chronic degenerative disorders and cancer, thus limiting early detection, risk stratification, and preventive interventions. Here, profiling the three chronic subt
Externí odkaz:
https://doaj.org/article/c4d0593a2b634f218289a7c2f4e8966d
Autor:
Jonas S. Jutzi, Anna E. Marneth, Michele Ciboddo, Angel Guerra-Moreno, María José Jiménez-Santos, Anastasia Kosmidou, James W. Dressman, Hongyan Liang, Rebecca Hamel, Patricia Lozano, Elisa Rumi, John G. Doench, Jason Gotlib, Anandi Krishnan, Shannon Elf, Fátima Al-Shahrour, Ann Mullally
Publikováno v:
Blood
Calreticulin (CALR) mutations are frequent, disease-initiating events in myeloproliferative neoplasms (MPNs). Although the biological mechanism by which CALR mutations cause MPNs has been elucidated, there currently are no clonally selective therapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcfceac4950ca83f59d94f418b10038c
https://doi.org/10.1182/blood.2022015629
https://doi.org/10.1182/blood.2022015629
Publikováno v:
bioRxiv
An altered thrombo-hemorrhagic profile has long been observed in patients with myeloproliferative neoplasms (MPNs). We hypothesized that this observed clinical phenotype may result from altered expression of genes known to harbor genetic variants in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f473adf6d5795f538a0f539fc6f3e1cf
https://europepmc.org/articles/PMC10245891/
https://europepmc.org/articles/PMC10245891/
Autor:
Sumanth Mosale Seetharam, Yi Liu, Jason Wu, Lenn Fechter, Kanagavel Murugesan, Holden Maecker, Jason Gotlib, James Zehnder, Ramasamy Paulmurugan, Anandi Krishnan
Impaired protein homeostasis, though well established in age-related disorders, has been linked in recent research with the pathogenesis of myeloproliferative neoplasms (MPNs). As yet, however, little is known about MPN-specific modulators of proteos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29b38d5fcfe2f95daa0dbdb54e7f388c
https://doi.org/10.1101/2023.01.07.523111
https://doi.org/10.1101/2023.01.07.523111
Autor:
Sally Thomas, Anandi Krishnan
Publikováno v:
Br J Cancer
Widespread adoption of next-generation techniques such as RNA-sequencing (RNA-seq) has enabled research examining the transcriptome of anucleate blood platelets in health and disease, thus revealing a rich platelet transcriptomic signature that is re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39154fa35acb27420f62cd2c49afa791
https://doi.org/10.1038/s41416-021-01627-z
https://doi.org/10.1038/s41416-021-01627-z
Autor:
Sally Thomas, Anandi Krishnan
Publikováno v:
Arterioscler Thromb Vasc Biol
Myeloproliferative neoplasms (MPNs) are a group of malignant disorders of the bone marrow where a dysregulated balance between proliferation and differentiation gives rise to abnormal numbers of mature blood cells. MPNs encompass a spectrum of diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6810f26f5846319c5984204fd813d6
https://doi.org/10.1161/atvbaha.121.316373
https://doi.org/10.1161/atvbaha.121.316373
Autor:
Jesse W. Rowley, James L. Zehnder, Jason Gotlib, Vanita Natu, Anandi Krishnan, Cecelia Perkins, Wenfei Du, Zhu Shen, Holden T. Maecker, Lenn Fechter
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100425-(2021)
Summary: Predicting disease progression remains a particularly challenging endeavor in chronic degenerative disorders and cancer, thus limiting early detection, risk stratification, and preventive interventions. Here, profiling the three chronic subt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9954dc4f2c73d2945813dec277fddb
http://www.sciencedirect.com/science/article/pii/S2666379121002871
http://www.sciencedirect.com/science/article/pii/S2666379121002871
Autor:
Masamitsu Kanada, Ramasamy Paulmurugan, Uday Kumar Sukumar, Anandi Krishnan, Yi Liu, Tarik F. Massoud
Publikováno v:
Adv Funct Mater
Camouflaged cell-membrane-based nanoparticles have been gaining increasing attention owing to their improved biocompatibility and immunomodulatory properties. Using nanoparticles prepared from the membranes of specific cell types, or fusions derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d733edfcb0a53121e413d97ccdb8760c
https://europepmc.org/articles/PMC8664068/
https://europepmc.org/articles/PMC8664068/