Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Ananda W, Goldrath"'
Autor:
Liwen Wang, Shruti Mishra, Kenneth Ka-Ho Fan, Sara Quon, Guo Li, Bingfei Yu, Wei Liao, Yong Liu, Xin Zhang, Yuanzheng Qiu, Yue Li, Ananda W. Goldrath, Chaoyu Ma, Nu Zhang
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114258- (2024)
Summary: Transforming growth factor β (TGF-β) represents a well-established signal required for tissue-resident memory T cell (TRM) formation at intestinal surfaces, regulating the expression of a large collection of genes coordinately promoting in
Externí odkaz:
https://doaj.org/article/3f93cc7958354e9c93628fd1fe83d0e5
Autor:
Brendan E. Russ, Adele Barugahare, Pushkar Dakle, Kirril Tsyganov, Sara Quon, Bingfei Yu, Jasmine Li, Jason K.C. Lee, Moshe Olshansky, Zhaohren He, Paul F. Harrison, Michael See, Simone Nussing, Alison E. Morey, Vibha A. Udupa, Taylah J. Bennett, Axel Kallies, Cornelis Murre, Phillipe Collas, David Powell, Ananda W. Goldrath, Stephen J. Turner
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113301- (2023)
Summary: The differentiation of naive CD8+ T lymphocytes into cytotoxic effector and memory CTL results in large-scale changes in transcriptional and phenotypic profiles. Little is known about how large-scale changes in genome organization underpin t
Externí odkaz:
https://doaj.org/article/a6421ddd15594daaa356a1bca492a4ba
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 9, p e1010116 (2022)
Transcription factors (TFs) are crucial for regulating cell differentiation during the development of the immune system. However, the key TFs for orchestrating the specification of distinct immune cells are not fully understood. Here, we integrated t
Externí odkaz:
https://doaj.org/article/bc7981ec099740778a7e8a256b3913c2
Autor:
Maximilian Heeg, Ananda W. Goldrath
Publikováno v:
Immunological Reviews.
Autor:
Quynh P. Nguyen, Kennidy K. Takehara, Tianda Z. Deng, Shannon O’Shea, Maximilian Heeg, Kyla D. Omilusik, J. Justin Milner, Sara Quon, Matthew E. Pipkin, Jinyong Choi, Shane Crotty, Ananda W. Goldrath
Publikováno v:
Science Immunology. 8
After resolution of infection, T cells differentiate into long-lived memory cells that recirculate through secondary lymphoid organs or establish residence in tissues. In contrast to CD8 + tissue-resident memory T cells (T RM ), the developmental ori
Autor:
John T. Crowl, Maximilian Heeg, Amir Ferry, J. Justin Milner, Kyla D. Omilusik, Clara Toma, Zhaoren He, John T. Chang, Ananda W. Goldrath
Publikováno v:
Nat Immunol
Nature immunology, vol 23, iss 7
Nature immunology, vol 23, iss 7
Tissue-resident memory T cells (T(RM) cells) provide protective immunity, but the contributions of specific tissue environments to T(RM) cell differentiation and homeostasis are not well understood. In the present study, the diversity of gene express
Autor:
Ananda W. Goldrath, Jack D. Bui, David J. Cole, Megan K. Baker, David H. Craig, J. Adam Best, Emilie T. Gross, Mark P. Rubinstein, Andrew L. Doedens
PyMT tumor versus spleen fold change, acute infection day 6 versus spleen fold change.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a8ba9b195fb816397409fa0c6e1b70
https://doi.org/10.1158/2326-6066.22537717
https://doi.org/10.1158/2326-6066.22537717
Autor:
Ananda W. Goldrath, Jack D. Bui, David J. Cole, Megan K. Baker, David H. Craig, J. Adam Best, Emilie T. Gross, Mark P. Rubinstein, Andrew L. Doedens
Selected phosphatases up-regulated in PyMT tumor CD8+ T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820700add58d7f6b53aa9dfc7f45fb9e
https://doi.org/10.1158/2326-6066.22537705.v1
https://doi.org/10.1158/2326-6066.22537705.v1
Autor:
Ananda W. Goldrath, Jack D. Bui, David J. Cole, Megan K. Baker, David H. Craig, J. Adam Best, Emilie T. Gross, Mark P. Rubinstein, Andrew L. Doedens
PyMT tumor CD8+ versus day 5 effector OT-I gene expression and fold change.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f83392c9f161140201446feeb0b064
https://doi.org/10.1158/2326-6066.22537723
https://doi.org/10.1158/2326-6066.22537723
Autor:
Ananda W. Goldrath, Jack D. Bui, David J. Cole, Megan K. Baker, David H. Craig, J. Adam Best, Emilie T. Gross, Mark P. Rubinstein, Andrew L. Doedens
Despite clinical potential and recent advances, durable immunotherapeutic ablation of solid tumors is not routinely achieved. IL15 expands natural killer cell (NK), natural killer T cell (NKT) and CD8+ T-cell numbers and engages the cytotoxic program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b950fdf94633ed97d2bceaa098bc4d01
https://doi.org/10.1158/2326-6066.c.6548530.v1
https://doi.org/10.1158/2326-6066.c.6548530.v1