Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Ananda A. Jaguva Vasudevan"'
Autor:
Aline Kaletsch, Maria Pinkerneil, Michèle J. Hoffmann, Ananda A. Jaguva Vasudevan, Chenyin Wang, Finn K. Hansen, Constanze Wiek, Helmut Hanenberg, Christoph Gertzen, Holger Gohlke, Matthias U. Kassack, Thomas Kurz, Wolfgang A. Schulz, Günter Niegisch
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-18 (2018)
Abstract Background Histone deacetylase inhibitors (HDACi) are promising anti-cancer drugs that could also be employed for urothelial carcinoma (UC) therapy. It is unclear, however, whether inhibition of all 11 zinc-dependent HDACs or of individual e
Externí odkaz:
https://doaj.org/article/e87d19bc77ef4eaa9cb7bb52c1e09692
Autor:
Ananda Ayyappan Jaguva Vasudevan, Dieter Häussinger, Carsten Münk, A Franken, Kannan Balakrishnan, Aikaterini Krikoni, Tom Luedde
Publikováno v:
Virology. 557:1-14
The human APOBEC3A (A3A) polynucleotide cytidine deaminase has been shown to have antiviral activity against HTLV-1 but not HIV-1, when expressed in the virus producer cell. In viral target cells, high levels of endogenous A3A activity have been asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f693a1cfe3cd1c8e6aabd687d2370ba
https://doi.org/10.1016/j.virol.2021.01.017
https://doi.org/10.1016/j.virol.2021.01.017
Autor:
Daniela Marino, Mario Perković, Anika Hain, Ananda A Jaguva Vasudevan, Henning Hofmann, Kay-Martin Hanschmann, Michael D Mühlebach, Gerald G Schumann, Renate König, Klaus Cichutek, Dieter Häussinger, Carsten Münk
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0155422 (2016)
APOBEC4 (A4) is a member of the AID/APOBEC family of cytidine deaminases. In this study we found a high mRNA expression of A4 in human testis. In contrast, there were only low levels of A4 mRNA detectable in 293T, HeLa, Jurkat or A3.01 cells. Ectopic
Externí odkaz:
https://doaj.org/article/d069d35ae6194d6e8b83106c7d23b739
Autor:
Satarupa Sarkar, Kannan Balakrishnan, Kumaraswami Chintala, Krishnaveni Mohareer, Tom Luedde, Ananda Ayyappan Jaguva Vasudevan, Carsten Münk, Sharmistha Banerjee
Publikováno v:
Viruses. 14:2503
Human immunodeficiency virus-1 (HIV-1) is a retrovirus that integrates its reverse-transcribed genome as proviral DNA into the host genome to establish a successful infection. The viral genome integration requires safeguarding the subviral complexes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0e35ac611bc6f421cf0c47877cce99
https://doi.org/10.3390/v14112503
https://doi.org/10.3390/v14112503
Publikováno v:
Viruses 13(3), 504 (2021). doi:10.3390/v13030504
Viruses, Vol 13, Iss 504, p 504 (2021)
Viruses
Viruses, Vol 13, Iss 504, p 504 (2021)
Viruses
Non-human primates (NHP) are an important source of viruses that can spillover to humans and, after adaptation, spread through the host population. Whereas HIV-1 and HTLV-1 emerged as retroviral pathogens in humans, a unique class of retroviruses cal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418289e2f37ca853f01207612da207f0
https://hdl.handle.net/2128/27456
https://hdl.handle.net/2128/27456
Autor:
Caroline Küstermann, Ulrike Held, Zeli Zhang, Anucha Sangwiman, Christoph G. W. Gertzen, Ananda Ayyappan Jaguva Vasudevan, Carsten Münk, Holger Gohlke, Dieter Häussinger, Kannan Balakrishnan, Gerald G. Schumann, Sharmistha Banerjee, Ignacio G. Bravo, Fanni Borvetó
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, In press, ⟨10.1016/j.jmb.2020.10.014⟩
Journal of Molecular Biology, Elsevier, In press, ⟨10.1016/j.jmb.2020.10.014⟩
Journal of molecular biology 432(23), 6200-6227 (2020). doi:10.1016/j.jmb.2020.10.014
Journal of Molecular Biology, In press, ⟨10.1016/j.jmb.2020.10.014⟩
Journal of Molecular Biology, Elsevier, In press, ⟨10.1016/j.jmb.2020.10.014⟩
Journal of molecular biology 432(23), 6200-6227 (2020). doi:10.1016/j.jmb.2020.10.014
APOBEC3 deaminases (A3s) provide mammals with an anti-retroviral barrier by catalyzing dC-to-dU deamination on viral ssDNA. Within primates, A3s have evolved diversely via gene duplications and fusions. Human APOBEC3C (hA3C) efficiently restricts the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f173f7aa0e2470af1cdf875c4cc854
https://pubmed.ncbi.nlm.nih.gov/33068636
https://pubmed.ncbi.nlm.nih.gov/33068636
Autor:
Ronald Swanstrom, Cecilia Martinez Campos, Bryan R. Cullen, Ann Emery, Ananda Ayyappan Jaguva Vasudevan, Kevin Tsai
Publikováno v:
Cell Host Microbe
Covalent modifications added to individual nucleotides on mRNAs, called epitranscriptomic modifications, have recently emerged as key regulators of both cellular and viral mRNA function1,2 and RNA methylation has now been shown to enhance the replica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5b353010c0a3cf90ce68aaeade17e0
https://doi.org/10.1101/2020.01.31.925578
https://doi.org/10.1101/2020.01.31.925578
Autor:
Patrick Petzsch, Karl Köhrer, Ananda Ayyappan Jaguva Vasudevan, Kai Stühler, Wolfgang A. Schulz, Michèle J. Hoffmann, Michael L. C. Beck, Gereon Poschmann, Constanze Wiek, Günter Niegisch
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2135 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 9
International Journal of Molecular Sciences
Volume 20
Issue 9
Class I histone deacetylases (HDACs) generally promote cell proliferation and tumorigenesis, whereas class IIA HDACs like HDAC4 and HDAC5 may promote or impede cancer development in a tissue-dependent manner. In urothelial carcinoma (UC), HDAC5 is of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fd3c622d5cb32db79129bca85c0a08
https://www.mdpi.com/1422-0067/20/9/2135
https://www.mdpi.com/1422-0067/20/9/2135
Autor:
Ananda Ayyappan Jaguva Vasudevan, Dieter Häussinger, Ariane Bähr, Carsten Münk, Anna Singer, Albert Zimmermann, Ramona Grothmann
Publikováno v:
Virology. 522
The MX dynamin GTPases inhibit diverse viruses at early post-entry phases. While MXA acts antiviral against influenza viruses, the anti HIV-1 activity of MXB was discovered recently. Here, we have studied the antiviral effect of MX proteins on murine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8491ba643fb937dc21ff9c57f249b520
https://pubmed.ncbi.nlm.nih.gov/30032029
https://pubmed.ncbi.nlm.nih.gov/30032029
Autor:
Ananda Ayyappan Jaguva Vasudevan, Baek Kim, Renate König, Karl S. Lang, Edmund Osei Kuffour, Jessica Holler, Kerstin Schott, Carsten Münk, Dieter Häussinger, Philipp A. Lang, Wolfgang A. Schulz
Publikováno v:
Journal of virology. 92(20)
The host intrinsic innate immune system drives antiviral defenses and viral restriction, which includes the production of soluble factors, such as type I and III interferon (IFN), and activation of restriction factors, including SAMHD1, a deoxynucleo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa250a9abdd57517a8d02a0e47e0da25
https://pubmed.ncbi.nlm.nih.gov/30068654
https://pubmed.ncbi.nlm.nih.gov/30068654