Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Ananda A. Jaguva Vasudevan"'
Autor:
Ananda Ayyappan Jaguva Vasudevan, Michèle J. Hoffmann, Gereon Poschmann, Patrick Petzsch, Constanze Wiek, Kai Stühler, Karl Köhrer, Wolfgang A. Schulz, Günter Niegisch
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-7 (2022)
Measurement(s) RNA-seq assay • Proteome Technology Type(s) Whole Transcriptome Sequencing • Mass spectrometry intensity based label-free quantification method Factor Type(s) Effect of HDAC5 overexpression in a range of urothelial cancer cells Sam
Externí odkaz:
https://doaj.org/article/31a9b4a026c34b6694b497aa3c502bac
Autor:
Satarupa Sarkar, Kannan Balakrishnan, Kumaraswami Chintala, Krishnaveni Mohareer, Tom Luedde, Ananda Ayyappan Jaguva Vasudevan, Carsten Münk, Sharmistha Banerjee
Publikováno v:
Viruses, Vol 14, Iss 11, p 2503 (2022)
Human immunodeficiency virus-1 (HIV-1) is a retrovirus that integrates its reverse-transcribed genome as proviral DNA into the host genome to establish a successful infection. The viral genome integration requires safeguarding the subviral complexes,
Externí odkaz:
https://doaj.org/article/0e9767c1d0fb480f80ad0098bfcd9c92
Autor:
Aline Kaletsch, Maria Pinkerneil, Michèle J. Hoffmann, Ananda A. Jaguva Vasudevan, Chenyin Wang, Finn K. Hansen, Constanze Wiek, Helmut Hanenberg, Christoph Gertzen, Holger Gohlke, Matthias U. Kassack, Thomas Kurz, Wolfgang A. Schulz, Günter Niegisch
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-18 (2018)
Abstract Background Histone deacetylase inhibitors (HDACi) are promising anti-cancer drugs that could also be employed for urothelial carcinoma (UC) therapy. It is unclear, however, whether inhibition of all 11 zinc-dependent HDACs or of individual e
Externí odkaz:
https://doaj.org/article/e87d19bc77ef4eaa9cb7bb52c1e09692
Autor:
Kannan Balakrishnan, Ananda Ayyappan Jaguva Vasudevan, Krishnaveni Mohareer, Tom Luedde, Carsten Münk, Sharmistha Banerjee
Publikováno v:
Viruses, Vol 13, Iss 12, p 2459 (2021)
Staufen, the RNA-binding family of proteins, affects various steps in the Human Immuno-Deficiency Virus (HIV-1) replication cycle. While our previous study established Staufen-2–HIV-1 Rev interaction and its role in augmenting nucleocytoplasmic exp
Externí odkaz:
https://doaj.org/article/abe8a53fe1ae4f5d86e49817c5d77498
Publikováno v:
Viruses, Vol 13, Iss 3, p 504 (2021)
Non-human primates (NHP) are an important source of viruses that can spillover to humans and, after adaptation, spread through the host population. Whereas HIV-1 and HTLV-1 emerged as retroviral pathogens in humans, a unique class of retroviruses cal
Externí odkaz:
https://doaj.org/article/24839b380ec5447ea96a143050858d70
Autor:
Ananda Ayyappan Jaguva Vasudevan, Ulrike Kreimer, Wolfgang A. Schulz, Aikaterini Krikoni, Gerald G. Schumann, Dieter Häussinger, Carsten Münk, Wolfgang Goering
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
The most common mutational signature in urothelial carcinoma (UC), the most common type of urinary bladder cancer is assumed to be caused by the misdirected activity of APOBEC3 (A3) cytidine deaminases, especially A3A or A3B, which are known to norma
Externí odkaz:
https://doaj.org/article/206e42af2cc946109c614327ae659c65
Autor:
Ananda Ayyappan Jaguva Vasudevan, Dieter Häussinger, Carsten Münk, A Franken, Kannan Balakrishnan, Aikaterini Krikoni, Tom Luedde
Publikováno v:
Virology. 557:1-14
The human APOBEC3A (A3A) polynucleotide cytidine deaminase has been shown to have antiviral activity against HTLV-1 but not HIV-1, when expressed in the virus producer cell. In viral target cells, high levels of endogenous A3A activity have been asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f693a1cfe3cd1c8e6aabd687d2370ba
https://doi.org/10.1016/j.virol.2021.01.017
https://doi.org/10.1016/j.virol.2021.01.017
Autor:
Daniela Marino, Mario Perković, Anika Hain, Ananda A Jaguva Vasudevan, Henning Hofmann, Kay-Martin Hanschmann, Michael D Mühlebach, Gerald G Schumann, Renate König, Klaus Cichutek, Dieter Häussinger, Carsten Münk
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0155422 (2016)
APOBEC4 (A4) is a member of the AID/APOBEC family of cytidine deaminases. In this study we found a high mRNA expression of A4 in human testis. In contrast, there were only low levels of A4 mRNA detectable in 293T, HeLa, Jurkat or A3.01 cells. Ectopic
Externí odkaz:
https://doaj.org/article/d069d35ae6194d6e8b83106c7d23b739
Autor:
Caroline Küstermann, Ulrike Held, Zeli Zhang, Anucha Sangwiman, Christoph G. W. Gertzen, Ananda Ayyappan Jaguva Vasudevan, Carsten Münk, Holger Gohlke, Dieter Häussinger, Kannan Balakrishnan, Gerald G. Schumann, Sharmistha Banerjee, Ignacio G. Bravo, Fanni Borvetó
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, In press, ⟨10.1016/j.jmb.2020.10.014⟩
Journal of Molecular Biology, Elsevier, In press, ⟨10.1016/j.jmb.2020.10.014⟩
Journal of molecular biology 432(23), 6200-6227 (2020). doi:10.1016/j.jmb.2020.10.014
Journal of Molecular Biology, In press, ⟨10.1016/j.jmb.2020.10.014⟩
Journal of Molecular Biology, Elsevier, In press, ⟨10.1016/j.jmb.2020.10.014⟩
Journal of molecular biology 432(23), 6200-6227 (2020). doi:10.1016/j.jmb.2020.10.014
APOBEC3 deaminases (A3s) provide mammals with an anti-retroviral barrier by catalyzing dC-to-dU deamination on viral ssDNA. Within primates, A3s have evolved diversely via gene duplications and fusions. Human APOBEC3C (hA3C) efficiently restricts the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f173f7aa0e2470af1cdf875c4cc854
https://pubmed.ncbi.nlm.nih.gov/33068636
https://pubmed.ncbi.nlm.nih.gov/33068636
Autor:
Ronald Swanstrom, Cecilia Martinez Campos, Bryan R. Cullen, Ann Emery, Ananda Ayyappan Jaguva Vasudevan, Kevin Tsai
Publikováno v:
Cell Host Microbe
Covalent modifications added to individual nucleotides on mRNAs, called epitranscriptomic modifications, have recently emerged as key regulators of both cellular and viral mRNA function1,2 and RNA methylation has now been shown to enhance the replica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5b353010c0a3cf90ce68aaeade17e0
https://doi.org/10.1101/2020.01.31.925578
https://doi.org/10.1101/2020.01.31.925578
