Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ananda, Herath"'
Autor:
Ananda Herath, Nicholas D. P. Cosford
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 239-246 (2017)
A versatile continuous-flow synthesis of highly functionalized 1,2,4-oxadiazoles starting from carboxylic acids is reported. This process was applied to the multistep synthesis of imidazo[1,2-a]pyridin-2-yl-1,2,4-oxadiazoles, using a three reactor, m
Externí odkaz:
https://doaj.org/article/da9ca7fb939f4e3ebed7d45e80dbfada
Autor:
Loren Jon, Ananda Herath, Andrew Valiere, Jim Yuchen Chang, Ashley Chong, Takaoki Koyanagi, Valentina Molteni, Maxim Ratnikov
Publikováno v:
Organic Letters. 21:816-820
A one-pot electrochemical nickel-catalyzed decarboxylative sp2–sp3 cross-coupling reaction has been developed using redox-active esters prepared in situ from alkyl carboxylates and N-hydroxyphthalimide tetramethyluronium hexafluorophosphate (PITU).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ceeadbd7c15ba78bfa538def6d6c078
https://doi.org/10.1021/acs.orglett.8b04090
https://doi.org/10.1021/acs.orglett.8b04090
Publikováno v:
Organic Letters. 20:7429-7432
A versatile flow synthesis method for in situ formation of organozinc reagents and subsequent cross-coupling with aryl halides and activated carboxylic acids is reported. Formation of organozinc reagents is achieved by pumping organic halides, in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29cd9e9aa7a2d0c72cc3a0fa548d2683
https://doi.org/10.1021/acs.orglett.8b03156
https://doi.org/10.1021/acs.orglett.8b03156
Publikováno v:
Tetrahedron. 74:3165-3170
Benzodiazepinones are privileged scaffolds with activity against multiple therapeutically relevant biological targets. In support of our ongoing studies around allosteric modulators of metabotropic glutamate receptors (mGlus) we required the multigra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7906d31b10db831d6914b1abb577f460
https://doi.org/10.1016/j.tet.2018.03.068
https://doi.org/10.1016/j.tet.2018.03.068
Autor:
Takaoki, Koyanagi, Ananda, Herath, Ashley, Chong, Maxim, Ratnikov, Andrew, Valiere, Jim, Chang, Valentina, Molteni, Jon, Loren
Publikováno v:
Organic letters. 21(3)
A one-pot electrochemical nickel-catalyzed decarboxylative sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4256a599c10d0a918795cb4812b564e2
https://pubmed.ncbi.nlm.nih.gov/30673257
https://pubmed.ncbi.nlm.nih.gov/30673257
Autor:
Svetlana Semenova, Athina Markou, Shyama Sidique, Robert Ardecky, P. Jeffrey Conn, Russell Dahl, Raveendra-Panickar Dhanya, Ananda Herath, Nicholas D. P. Cosford, Douglas J. Sheffler, Li Yang, Hilary Highfield Nickols
Publikováno v:
Journal of Medicinal Chemistry. 54:342-353
The modification of 3′-((2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yloxy)methyl)biphenyl-4-carboxylic acid (BINA, 1) by incorporating heteroatoms into the structure and replacing the cyclopentyl moiety led to the development of new mG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcdb021d93fc36507b062a546e63c08
https://doi.org/10.1021/jm1012165
https://doi.org/10.1021/jm1012165
Publikováno v:
Journal of the American Chemical Society. 131:17024-17029
Strategies for the reductive coupling of enones or enals with alkynes have been developed. The reducing agents employed include organozincs, organoboranes, organosilanes, and methanol. The latter of these strategies is simple, cost-effective, and tol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13389c2a4fbb00bb51fc3018d07939e7
https://doi.org/10.1021/ja9083607
https://doi.org/10.1021/ja9083607
Autor:
Nicholas D. P. Cosford, Boris I. Ratnikov, Sergey A. Shiryaev, Alex Y. Strongin, Ananda Herath, Shyama Sidique, Ying Su
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:5773-5777
West Nile Virus (WNV) is a potentially deadly mosquito-borne flavivirus which has spread rapidly throughout the world. Currently there is no effective vaccine against flaviviral infections. We previously reported the identification of pyrazole ester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea815e5df39b961828f44a43199d047f
https://doi.org/10.1016/j.bmcl.2009.07.150
https://doi.org/10.1016/j.bmcl.2009.07.150
Publikováno v:
Journal of Materials in Civil Engineering. 19:986-992
Current pavement design procedures recommend the resilient modulus of subgrade materials for pavement design and analysis. The objective of this paper is to develop two statistical models to predict the resilient modulus of subgrade cohesive soils fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a677c8ee037ef54d49e76a9ce3d110e
https://doi.org/10.1061/(asce)0899-1561(2007)19:11(986)
https://doi.org/10.1061/(asce)0899-1561(2007)19:11(986)
Publikováno v:
Transportation Research Record: Journal of the Transportation Research Board. 1967:78-88
Pavement performance is related to resilient modulus and permanent deformation properties of pavement materials, as well as other factors such as environmental and traffic conditions. Current resilient modulus test procedures and correlations do not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::837b8227017869e33955e3ec22dc5aec
https://doi.org/10.1177/0361198106196700109
https://doi.org/10.1177/0361198106196700109