Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Anand S. Ramaian"'
Autor:
Sneha Mishra, Claudia Cosentino, Ankit Kumar Tamta, Danish Khan, Shalini Srinivasan, Venkatraman Ravi, Elena Abbotto, Bangalore Prabhashankar Arathi, Shweta Kumar, Aditi Jain, Anand S. Ramaian, Shruti M. Kizkekra, Raksha Rajagopal, Swathi Rao, Swati Krishna, Ninitha Asirvatham-Jeyaraj, Elizabeth R. Haggerty, Dafne M. Silberman, Irwin J. Kurland, Ravindra P. Veeranna, Tamilselvan Jayavelu, Santina Bruzzone, Raul Mostoslavsky, Nagalingam R. Sundaresan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Chronic stress induces skeletal muscle atrophy via upregulation of glucocorticoid levels. Here, the authors show that SIRT6 transcriptionally regulates glucocorticoid-induced muscle atrophy by modulating IGF/PI3K/AKT signalling.
Externí odkaz:
https://doaj.org/article/d4cbf3bac7a14798ba51e0d8aeaeb195
Autor:
Kannan Subramanian, Anand S Ramaian
Publikováno v:
Bioinformation
Dichloroacetate (DCA) is a synthetic compound that promotes the activity of pyruvate dehydrogenase (PDH) by inhibiting its repressor protein called pyruvate dehydrogenase kinase (PDHK). The activation of PDH leads to a reduction in ambient cellular l