Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anand S. Chintakrindi"'
Publikováno v:
Medicinal Chemistry Research. 27:1013-1025
A series of chalcone derivatives (1a–2i) were designed based on isoliquiritigenin (the most active natural chalcone non-competitive neuraminidase (NA) inhibitor). Molecular modeling studies revealed that isoliquiritigenin and its designed analogs o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7d4b4bde3cceac9eae51f741a482824
https://doi.org/10.1007/s00044-017-2124-2
https://doi.org/10.1007/s00044-017-2124-2
Autor:
Devanshi J. Gohil, Abhay Chowdhary, Sudha Srivastava, Sweta T. Kothari, Anand S. Chintakrindi, Mamata Joshi, H. Gonsalves, Khushboo D Malbari, Meena Kanyalkar
Publikováno v:
Acta virologica. 62:179-190
Considering the need for discovery of new antiviral drugs, in view to combat the issue of resistance particularly to anti-influenza drugs, a series of 2'-amino, 3'-amino and 2', 4'-dihydroxy chalcone derivatives were designed. Structure-based drug de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3f4155822d4db80195277ba1b5058f
https://doi.org/10.4149/av_2018_209
https://doi.org/10.4149/av_2018_209
Publikováno v:
Bioorganicmedicinal chemistry. 28(1)
We designed a series of substituted flavones and aurones as non-competitive H1N1 neuraminidase (NA) inhibitors and anti-influenza agents. The molecular docking studies showed that the designed flavones and aurones occupied 150-cavity and 430-cavity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c1c20eed10b849c3de52c7945ce08a
https://pubmed.ncbi.nlm.nih.gov/31744778
https://pubmed.ncbi.nlm.nih.gov/31744778
Autor:
Abhay Chowdhary, Anand S. Chintakrindi, Devanshi J. Gohil, Elvis A. F. Martis, Evans C. Coutinho, Meena Kanyalkar, Sweta T. Kothari
Publikováno v:
Current Computer Aided-Drug Design. 12:272-281
Background: With cases of emergence of drug resistance to the current competitive inhibitors of neuraminidase (NA) such as oseltamivir and zanamavir, there is a present need for an alternative approach in the treatment of avian influenza. With this i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c7e7becaad470c9a3c33e0ba1748f6
https://doi.org/10.2174/1573409912666160713111242
https://doi.org/10.2174/1573409912666160713111242
Autor:
Khushboo D Malbari, Sweta T. Kothari, Anand S. Chintakrindi, Meena Kanyalkar, Devanshi J. Gohil, Lata R. Ganji, Mamata Joshi
Publikováno v:
Molecular diversity. 23(4)
The rate of mutability of pathogenic H1N1 influenza virus is a threat. The emergence of drug resistance to the current competitive inhibitors of neuraminidase, such as oseltamivir and zanamivir, attributes to a need for an alternative approach. The d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02d9bf7f65636751714a2eab87618cd
https://pubmed.ncbi.nlm.nih.gov/30710224
https://pubmed.ncbi.nlm.nih.gov/30710224
Autor:
Anand S. Chintakrindi, Sweta T. Kothari, Pramod Shinde, Abhay Chowdhary, Meena Kanyalkar, Devanshi J. Gohil, Rhuta Meharunkar, Ranjana A Deshmukh, Rajas Warke
Publikováno v:
Infection, Genetics and Evolution. 29:75-81
Objective From its first instance in 1977, resistance to amantadine, a matrix (M2) inhibitor has been increasing among influenza A/H3N2, thus propelling the use of oseltamivir, a neuraminidase (NA) inhibitor as a next line drug. Information on drug s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66b2ca7d4126643540c8cfa1bcbf27b
https://doi.org/10.1016/j.meegid.2014.11.005
https://doi.org/10.1016/j.meegid.2014.11.005
Publikováno v:
Mini reviews in medicinal chemistry. 12(12)
The highly pathogenic influenza virus has caused many human fatalities and poses an increasing pandemic threat. Neuraminidase inhibitors such as oseltamivir and zanamivir have been widely used in the treatment and have gained remarkable success. Alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0859b4afe587eeea38b0ed14162a0f3f
https://pubmed.ncbi.nlm.nih.gov/22512586
https://pubmed.ncbi.nlm.nih.gov/22512586
Publikováno v:
Journal of molecular modeling. 18(4)
The availability of the crystal structure of falcipain-3, knowledge of the peptides carrying the 7-aminocoumarin moiety as falcipain-3 ligands/substrates, and a need for new antimalarial agents stimulated us to look at the possibility of finding some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457b8315ded290b96d55a5123a0a2e69
https://pubmed.ncbi.nlm.nih.gov/21785935
https://pubmed.ncbi.nlm.nih.gov/21785935