Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Anand S, Mehta"'
Autor:
Mengjun Wang, Stephane Grauzam, Muhammed Furkan Bayram, James Dressman, Andrew DelaCourt, Calvin Blaschke, Hongyan Liang, Danielle Scott, Gray Huffman, Alyson Black, Shaaron Ochoa-Rios, David Lewin, Peggi M. Angel, Richard R. Drake, Lauren Ball, Jennifer Bethard, Stephen Castellino, Yuko Kono, Naoto Kubota, Yujin Hoshida, Lisa Quirk, Adam Yopp, Purva Gopal, Amit Singal, Anand S. Mehta
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract Background Worldwide, hepatocellular carcinoma (HCC) is the second most lethal cancer, although early-stage HCC is amenable to curative treatment and can facilitate long-term survival. Early detection has proved difficult, as proteomics, tra
Externí odkaz:
https://doaj.org/article/46176303e9b94dac90d72d3c6c970e82
Autor:
Stephen C. Zambrzycki, Samaneh Saberi, Rachel Biggs, Najmeh Eskandari, Davide Delisi, Harrison Taylor, Anand S. Mehta, Richard R. Drake, Saverio Gentile, Amy D. Bradshaw, Michael Ostrowski, Peggi M. Angel
Publikováno v:
Matrix Biology Plus, Vol 24, Iss , Pp 100161- (2024)
While numerous approaches have been reported towards understanding single cell regulation, there is limited understanding of single cell production of extracellular matrix phenotypes. Collagens are major proteins of the extracellular microenvironment
Externí odkaz:
https://doaj.org/article/8655775cea6947d09f3fda8438964bbe
Autor:
Elizabeth N. Wallace, Connor A. West, Colin T. McDowell, Xiaowei Lu, Evelyn Bruner, Anand S. Mehta, Kiyoko F. Aoki-Kinoshita, Peggi M. Angel, Richard R. Drake
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract N-glycosylation is an abundant post-translational modification of most cell-surface proteins. N-glycans play a crucial role in cellular functions like protein folding, protein localization, cell–cell signaling, and immune detection. As dif
Externí odkaz:
https://doaj.org/article/b99fe5bd597d4068ad3081f8fb25956f
Autor:
Lyndsay E. A. Young, Paul J. Nietert, Rachel Stubler, Caroline G. Kittrell, Grace Grimsley, David N. Lewin, Anand S. Mehta, Chadi Hajar, Katherine Wang, Elizabeth C. O’Quinn, Peggi M. Angel, Kristin Wallace, Richard R. Drake
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Colorectal cancer (CRC) stands as a leading cause of death worldwide, often arising from specific genetic mutations, progressing from pre-cancerous adenomas to adenocarcinomas. Early detection through regular screening can result in a 90% 5-year surv
Externí odkaz:
https://doaj.org/article/2a26f4a5a123444dbc5e34be62f87024
Autor:
Calvin R. K. Blaschke, Elizabeth G. Hill, Anand S. Mehta, Peggi M. Angel, Christine Laronga, Richard R. Drake
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract While mammograms are the standard tool for breast cancer screening, there remains challenges for mammography to effectively distinguish benign lesions from breast cancers, leading to many unnecessary biopsy procedures. A blood-based biomarke
Externí odkaz:
https://doaj.org/article/30039b74b35f4833a22c6d10854fdf4e
Autor:
Benjamin Samuel Haslund-Gourley, Stéphane Grauzam, Anand S. Mehta, Brian Wigdahl, Mary Ann Comunale
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Lyme disease (LD) infection is caused by Borrelia burgdorferi sensu lato (Bb). Due to the limited presence of this pathogen in the bloodstream in humans, diagnosis of LD relies on seroconversion. Immunoglobulins produced in response to infection are
Externí odkaz:
https://doaj.org/article/5f5afd73120342ac9d2465520f56f12c
Autor:
Cassandra L. Clift, Yan Ru Su, David Bichell, Heather C. Jensen Smith, Jennifer R. Bethard, Kim Norris-Caneda, Susana Comte-Walters, Lauren E. Ball, M. A. Hollingsworth, Anand S. Mehta, Richard R. Drake, Peggi M. Angel
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Congenital aortic valve stenosis (CAVS) affects up to 10% of the world population without medical therapies to treat the disease. New molecular targets are continually being sought that can halt CAVS progression. Collagen deregulation is a h
Externí odkaz:
https://doaj.org/article/f870ac3e8279454988ad55f7c7a0b959
Autor:
Denys Rujchanarong, Danielle Scott, Yeonhee Park, Sean Brown, Anand S. Mehta, Richard Drake, George E. Sandusky, Harikrishna Nakshatri, Peggi M. Angel
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
A primary difference between black women (BW) and white women (WW) diagnosed with breast cancer is aggressiveness of the tumor. Black women have higher mortalities with similar incidence of breast cancer compared to other race/ethnicities, and they a
Externí odkaz:
https://doaj.org/article/ad6b7b1988c4497c8983ac99137ded23
Autor:
Danielle A. Scott, Mengjun Wang, Stephane Grauzam, Sarah Pippin, Alyson Black, Peggi M. Angel, Richard R. Drake, Stephen Castellino, Yuko Kono, Don C. Rockey, Anand S. Mehta
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Our group has recently developed the GlycoTyper assay which is a streamlined antibody capture slide array approach to directly profile N-glycans of captured serum glycoproteins including immunoglobulin G (IgG). This method needs only a few microliter
Externí odkaz:
https://doaj.org/article/8a44d0110f1a4b68bb8d426dd1c11463
Autor:
Xiaowei Lu, Colin T. McDowell, Calvin R. K. Blaschke, Liping Liu, Grace Grimsley, Luke Wisniewski, ChongFeng Gao, Anand S. Mehta, Brian B. Haab, Peggi M. Angel, Richard R. Drake
Publikováno v:
Analytical Chemistry. 95:7475-7486