Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Anand Rotte"'
Autor:
Anand Rotte
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/8fa04f85681b4d22931fade7390683cc
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-10 (2023)
Abstract CAR-T cells are widely recognized for their potential to successfully treat hematologic cancers and provide durable response. However, severe adverse events such as cytokine release syndrome (CRS) and neurotoxicity are concerning. Our goal i
Externí odkaz:
https://doaj.org/article/bc11f9c5d417482aa163c574c355e2e3
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
The potential of chimeric antigen receptor (CAR) T cells to successfully treat hematological cancers is widely recognized. Multiple CAR-T cell therapies are currently under clinical development, with most in early stage, during which dose selection i
Externí odkaz:
https://doaj.org/article/a995f695359c4c84a198dd6a34b4b3b3
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Abstract The success of antibodies targeting Programmed cell death protein 1 (PD-1) and its ligand L1 (PD-L1) in cancer treatment and the need for improving response rates has led to an increased demand for the development of combination therapies wi
Externí odkaz:
https://doaj.org/article/8fd63636c8a94477b7f1c1f85769589f
Autor:
Anand Rotte
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-12 (2019)
Abstract Targeting checkpoints of immune cell activation has been demonstrated to be the most effective approach for activation of anti-tumor immune responses. Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (
Externí odkaz:
https://doaj.org/article/d8eb374f8cb6425b95e04acf0c2955d7
Publikováno v:
Journal of International Medical Research, Vol 49 (2021)
There are limited treatment options for patients with foot drop and associated lower back and/or leg pain. We present a case series of three patients who received permanent implantation of 10 kHz spinal cord stimulation (10 kHz SCS) devices. Followin
Externí odkaz:
https://doaj.org/article/54a7afdbbd094e42bf05c2043da7be3a
Publikováno v:
Pain Research and Management, Vol 2021 (2021)
Background. Spinal cord stimulation (SCS) has been used over decades for pain management, but migration of percutaneous leads has been the most common complication. Better surgical techniques and newer SCS technologies likely reduced the incidence of
Externí odkaz:
https://doaj.org/article/76da0c4991d443e384bf215ff6253a90
Autor:
Ashley Bailey-Classen, Amar Parikh, Nima Adimi, Deborah Edgar, Alice Yan, Anand Rotte, David Caraway
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 497 (2022)
In the rapidly evolving field of spinal cord stimulation (SCS), measures of treatment effects are needed to help understand the benefits of new therapies. The present article elaborates the number needed to treat (NNT) concept and applies it to the S
Externí odkaz:
https://doaj.org/article/0abb731d967746e998d505225a51999a
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1277 (2021)
Immune checkpoint blockers have dramatically improved the chances of survival in patients with metastatic cancer, but only a subset of the patients respond to treatment. Search for novel targets that can improve the responder rates and overcome the l
Externí odkaz:
https://doaj.org/article/1ff2710bd4dd4b988ef4bc425a0d3124
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-3 (2018)
Abstract This commentary wishes to highlight the 2018 Nobel Prize in Medicine awarded to two cancer immunotherapy scientists, Prof James Allison and Prof Tasuku Honjo, for their discovery on unleashing the body’s immune system to attack cancer. The
Externí odkaz:
https://doaj.org/article/399f7f2f2b074e69a42be0e9bcf71519