Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Anand R. Asthagiri"'
Publikováno v:
PLoS ONE, Vol 15, Iss 9 (2020)
Epithelial-to-mesenchymal transition (EMT) and maturation of a fibrillar tumor microenvironment play important roles in breast cancer progression. A better understanding of how these events promote cancer cell migration and invasion could help identi
Externí odkaz:
https://doaj.org/article/e6d731ac923843409fbeda53a52682c4
Autor:
Stephen A Chapman, Anand R Asthagiri
Publikováno v:
Molecular Systems Biology, Vol 5, Iss 1, Pp 1-6 (2009)
Abstract Protein scaffolds bring together multiple components of a signalling pathway, thereby promoting signal propagation along a common physical ‘backbone’. Scaffolds play a prominent role in natural signalling pathways and provide a promising
Externí odkaz:
https://doaj.org/article/340f91c76c7f447b93b53250f4a31cea
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239188 (2020)
PLoS ONE
PLoS ONE
Epithelial-to-mesenchymal transition (EMT) and maturation of a fibrillar tumor microenvironment play important roles in breast cancer progression. A better understanding of how these events promote cancer cell migration and invasion could help identi
Epithelial-to-mesenchymal transition (EMT) and maturation of collagen fibrils in the tumor microenvironment play a significant role in cancer cell invasion and metastasis. Confinement along fiber-like tracks enhances cell migration. To what extent an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a67030bf4f8579ab08deb0bfe03469
https://doi.org/10.1101/308536
https://doi.org/10.1101/308536
Autor:
Mark L. Lalli, Anand R. Asthagiri
Publikováno v:
Cellular and Molecular Bioengineering. 8:247-257
During development and disease, cells migrate collectively in response to gradients in physical, chemical and electrical cues. Despite its physiological significance and potential therapeutic applications, electrotactic collective cell movement is re
Publikováno v:
Current Opinion in Biotechnology. 24:940-947
Juxtacrine cell-cell signaling mediated by the direct interaction of adjoining mammalian cells is arguably the mode of cell communication that is most recalcitrant to engineering. Overcoming this challenge is crucial for progress in biomedical applic
Collective cell migration plays an important role in wound healing, organogenesis, and the progression of metastatic disease. Analysis of collective migration typically involves laborious and time-consuming manual tracking of individual cells within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab258ec6437ab3ab965dc2656805c10e
https://europepmc.org/articles/PMC6816619/
https://europepmc.org/articles/PMC6816619/
The breast tumor microenvironment (TMEN) is a unique niche where protein fibers help to promote invasion and metastasis. Cells migrating along these fibers are constantly interacting with each other. How cells respond to these interactions has import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3756fadf522a02588f04a80b2a765158
https://europepmc.org/articles/PMC4850354/
https://europepmc.org/articles/PMC4850354/
Autor:
Anand R. Asthagiri, Daniel F. Milano, Senthil K. Muthuswamy, Catherine Y. Luo, Robert J Natividad, Yasuhiro Saito
Publikováno v:
Biophysical journal. 111(7)
Epithelial-mesenchymal transition (EMT) is a complex process by which cells acquire invasive properties that enable escape from the primary tumor. Complete EMT, however, is not required for metastasis: circulating tumor cells exhibit hybrid epithelia
Extent of EMT promotes invasive, contact-induced sliding on progressively narrower fiber-like tracks
Epithelial-mesenchymal transition (EMT) is a complex process by which cells acquire invasive properties that enable escape from the primary tumor. Complete EMT, however, is not required for metastasis: circulating tumor cells exhibit hybrid epithelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4867ce6d9801da4a8c4e7bd0dfb4a75b