Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Anand R Nair"'
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243207 (2020)
BackgroundIntramyocardial hemorrhage following reperfusion is strongly associated with major adverse cardiovascular events in myocardial infarction (MI) patients; yet the mechanisms contributing to these outcomes are not well understood. Large animal
Externí odkaz:
https://doaj.org/article/763d66a17c0141b6b0b3a184de32ad41
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0160923 (2016)
Post-traumatic stress disorder (PTSD) is a trauma and stressor-related disorder that results in a prolonged stress response. It is associated with increased oxidative stress and inflammation in the prefrontal cortex (PFC) and hippocampus (HC). The on
Externí odkaz:
https://doaj.org/article/98ecd31867804db39bf7fe5cc4f04a52
Autor:
Gustavo S Masson, Anand R Nair, Rahul B Dange, Pedro Paulo Silva-Soares, Lisete C Michelini, Joseph Francis
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122850 (2015)
Toll-like receptor 4 (TLR4) signaling induces tissue pro-inflammatory cytokine release and endoplasmic reticulum (ER) stress. We examined the role of TLR4 in autonomic dysfunction and the contribution of ER stress.Our study included animals divided i
Externí odkaz:
https://doaj.org/article/dfd9302cb75a4048b630d95d18f059c1
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111976 (2014)
Metabolic syndrome (MetS) is characterized by a cluster of health factors that indicate a higher risk for cardio-renal diseases. Recent evidence indicates that antioxidants from berries are alternative to attenuate oxidative stress and inflammation.
Externí odkaz:
https://doaj.org/article/b512b3c0141c4428baf904654a9075e3
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58339 (2013)
The binding of renin or prorenin to the (pro)renin receptor (PRR) promotes angiotensin (Ang) II formation and mediates Ang II-independent signaling pathways. In the central nervous system (CNS), Ang II regulates blood pressure via inducing oxidative
Externí odkaz:
https://doaj.org/article/cdd4a632df794b98a8c6fbf836ab632c
Autor:
Ivan Cokic, Shing Fai Chan, Xingmin Guan, Anand R. Nair, Hsin-Jung Yang, Ting Liu, Yinyin Chen, Diego Hernando, Jane Sykes, Richard Tang, John Butler, Alice Dohnalkova, Libor Kovarik, Robert Finney, Avinash Kali, Behzad Sharif, Louis S. Bouchard, Rajesh Gupta, Mayil Singaram Krishnam, Keyur Vora, Balaji Tamarappoo, Andrew G. Howarth, Andreas Kumar, Joseph Francis, Scott B. Reeder, John C. Wood, Frank S. Prato, Rohan Dharmakumar
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
It is unclear why hemorrhagic myocardial infarctions (hMI) are destined for adverse outcomes. Here, the authors show that hMI drives fatty degeneration of infarct territories and contributes to adverse remodeling of the heart, which can be mitigated
Externí odkaz:
https://doaj.org/article/3fcbb124b97648aaa977eecd97230304
Publikováno v:
Frontiers in Cardiovascular Medicine. 10
Toll-like receptor 4 (TLR4) is an integral factor in the initiation of the innate immune response and plays an important role in cardiovascular diseases such as hypertension and myocardial infarction. Previous studies from our lab demonstrated that c
Publikováno v:
JACC: Basic to Translational Science
Corresponding Author
Autor:
Jing Wu, Shi Fang, Ko-Ting Lu, Gaurav Kumar, John J Reho, Daniel T Brozoski, Adokole J Otanwa, Chunyan Hu, Anand R Nair, Kelsey K Wackman, Larry N Agbor, Justin L Grobe, Curt D Sigmund
Publikováno v:
Function (Oxford, England). 3(3)
Human hypertension caused by in-frame deletion of CULLIN3 exon-9 (Cul3∆9) is driven by renal and vascular mechanisms. We bred conditionally activatable Cul3∆9 transgenic mice with tamoxifen-inducible Tie2-CREERT2 mice to test the importance of en
Publikováno v:
Inventive Computation and Information Technologies ISBN: 9789811667220
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b35f3e47184cd8e5763f475219fa8366
https://doi.org/10.1007/978-981-16-6723-7_12
https://doi.org/10.1007/978-981-16-6723-7_12