Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Anand Mayakonda"'
Autor:
Charlotte Smith, Ashish Goyal, Dieter Weichenhan, Eric Allemand, Anand Mayakonda, Umut Toprak, Anna Riedel, Estelle Balducci, Manisha Manojkumar, Anastasija Pejkovska, Oliver Mücke, Etienne Sollier, Ali Bakr, Kersten Breuer, Pavlo Lutsik, Olivier Hermine, Salvatore Spicuglia, Vahid Asnafi, Christoph Plass, Aurore Touzart
Publikováno v:
Haematologica, Vol 108, Iss 5 (2023)
T-cell acute lymphocytic leukemia protein 1 (TAL1) is one of the most frequently deregulated oncogenes in T-cell acute lymphoblastic leukemia (T-ALL). Its deregulation can occur through diverse cis-alterations, including SIL-TAL1 microdeletions, tran
Externí odkaz:
https://doaj.org/article/6e9c05fc1a7f4ebda3d21c7b4a8a919f
Autor:
Pavlo Lutsik, Annika Baude, Daniela Mancarella, Simin Öz, Alexander Kühn, Reka Toth, Joschka Hey, Umut H. Toprak, Jinyeong Lim, Viet Ha Nguyen, Chao Jiang, Anand Mayakonda, Mark Hartmann, Felix Rosemann, Kersten Breuer, Dominik Vonficht, Florian Grünschläger, Suman Lee, Maren Kirstin Schuhmacher, Denis Kusevic, Anna Jauch, Dieter Weichenhan, Jozef Zustin, Matthias Schlesner, Simon Haas, Joo Hyun Park, Yoon Jung Park, Udo Oppermann, Albert Jeltsch, Florian Haller, Jörg Fellenberg, Anders M. Lindroth, Christoph Plass
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The histone variant mutation H3.3-G34W occurs in the majority of giant cell tumor of bone (GCTB). By profiling patient-derived GCTB tumor cells, the authors show that this mutation associates with epigenetic alterations in heterochromatic and bivalen
Externí odkaz:
https://doaj.org/article/0ca3a08070bf40f2a72b5ae76155d70a
Autor:
Ye Chen, Liang Xu, Anand Mayakonda, Mo-Li Huang, Deepika Kanojia, Tuan Zea Tan, Pushkar Dakle, Ruby Yu-Tong Lin, Xin-Yu Ke, Jonathan W. Said, Jianxiang Chen, Sigal Gery, Ling-Wen Ding, Yan-Yi Jiang, Angela Pang, Mark Edward Puhaindran, Boon Cher Goh, H. Phillip Koeffler
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Liposarcoma (LPS) is a rare cancer that can acquire resistance to chemotherapy. Here, the authors map super-enhancers in LPS, finding BET-protein dependent mechanisms that can be targeted by a BET protein degrader, which also can overcome acquired re
Externí odkaz:
https://doaj.org/article/737f0325add94122b8c3c1a96fabd32f
Autor:
Kar-Tong Tan, Ling-Wen Ding, Qiao-Yang Sun, Zhen-Tang Lao, Wenwen Chien, Xi Ren, Jin-Fen Xiao, Xin Yi Loh, Liang Xu, Michael Lill, Anand Mayakonda, De-Chen Lin, Henry Yang, H. Phillip Koeffler
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
Abstract Background Clonal VDJ rearrangement of B/T cell receptors (B/TCRs) occurring during B/T lymphocyte development has been used as a marker to track the clonality of B/T cell populations. Methods We systematically profiled the B/T cell receptor
Externí odkaz:
https://doaj.org/article/ab73d11ede72491d9a1d5693f9503c26
Autor:
Yuan Jiang, Yan-Yi Jiang, Jian-Jun Xie, Anand Mayakonda, Masaharu Hazawa, Li Chen, Jin-Fen Xiao, Chun-Quan Li, Mo-Li Huang, Ling-Wen Ding, Qiao-Yang Sun, Liang Xu, Deepika Kanojia, Maya Jeitany, Jian-Wen Deng, Lian-Di Liao, Harmik J. Soukiasian, Benjamin P. Berman, Jia-Jie Hao, Li-Yan Xu, En-Min Li, Ming-Rong Wang, Xin-Gang Bi, De-Chen Lin, H. Phillip Koeffler
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Master regulator transcription factors TP63 and SOX2 have been reported to overlap in genomic occupancy in squamous cell carcinomas (SCCs). Here, the authors demonstrate that TP63 and SOX2 promote co-operatively long non-coding RNA CCAT1 expression t
Externí odkaz:
https://doaj.org/article/f927ec3e43a241b38907cdd1a8dba8c5
Autor:
Ling-Wen Ding, Qiao-Yang Sun, Anand Mayakonda, Kar-Tong Tan, Wenwen Chien, De-Chen Lin, Yan-Yi Jiang, Liang Xu, Manoj Garg, Zhen-Tang Lao, Michael Lill, Henry Yang, Allen Eng Juh Yeoh, H. Phillip Koeffler
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-4 (2017)
Abstract Relapsed acute lymphoblastic leukemia (ALL) is the leading cause of deaths of childhood cancer. Although relapse usually happens in the bone marrow, extramedullary relapse occasionally occurs including either the central nervous system or te
Externí odkaz:
https://doaj.org/article/2d6945d891304993add00aa0d096eaaf
Autor:
Zhen-Tang Lao, Ling-Wen Ding, Omer An, Norimichi Hattori, Qiao-Yang Sun, Kar-Tong Tan, Anand Mayakonda, Wong Gee Chuan, Vikas Madan, De-Chen Lin, Henry Yang, H. Phillip Koeffler
Publikováno v:
Haematologica, Vol 104, Iss 5 (2019)
Externí odkaz:
https://doaj.org/article/77c67a7b15774efc9fcef5c2921a3d7f
Autor:
Vikas Madan, Lin Han, Norimichi Hattori, Weoi Woon Teoh, Anand Mayakonda, Qiao-Yang Sun, Ling-Wen Ding, Hazimah Binte Mohd Nordin, Su Lin Lim, Pavithra Shyamsunder, Pushkar Dakle, Janani Sundaresan, Ngan B. Doan, Masashi Sanada, Aiko Sato-Otsubo, Manja Meggendorfer, Henry Yang, Jonathan W. Said, Seishi Ogawa, Torsten Haferlach, Der-Cherng Liang, Lee-Yung Shih, Tsuyoshi Nakamaki, Q. Tian Wang, H. Phillip Koeffler
Publikováno v:
Haematologica, Vol 103, Iss 12 (2018)
Chromosomal translocation t(8;21)(q22;q22) which leads to the generation of oncogenic RUNX1-RUNX1T1 (AML1-ETO) fusion is observed in approximately 10% of acute myelogenous leukemia (AML). To identify somatic mutations that co-operate with t(8;21)-dri
Externí odkaz:
https://doaj.org/article/ab6ad18f04b84ee8a7ee0e0cf60a7d89
Autor:
Pavithra Shyamsunder, Haresh Sankar, Anand Mayakonda, Lin Han, Hazimah Binte Mohd Nordin, Teoh Weoi Woon, Mahalakshmi Shanmugasundaram, Pushkar Dakle, Vikas Madan, H. Phillip Koeffler
Publikováno v:
Haematologica, Vol 103, Iss 8 (2018)
Maturation of granulocytes is dependent on controlled gene expression by myeloid lineage restricted transcription factors. CEBPE is one of the essential transcription factors required for granulocytic differentiation. Identification of downstream tar
Externí odkaz:
https://doaj.org/article/395f446f58d945c1b4d1c49dca432bed
Autor:
Deepti Talwar, Colin G. Miller, Justus Grossmann, Lukasz Szyrwiel, Torsten Schwecke, Vadim Demichev, Ana-Matea Mikecin Drazic, Anand Mayakonda, Pavlo Lutsik, Carmen Veith, Michael D. Milsom, Karin Müller-Decker, Michael Mülleder, Markus Ralser, Tobias P. Dick
Publikováno v:
Nature Metabolism. 5:660-676
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is known to contain an active-site cysteine residue undergoing oxidation in response to hydrogen peroxide, leading to rapid inactivation of the enzyme. Here we show that human and mouse cells expressin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4874348d43578ad40f44fe3760e1e2d
https://doi.org/10.1038/s42255-023-00781-3
https://doi.org/10.1038/s42255-023-00781-3