Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Anand Krishnan V. Iyer"'
Publikováno v:
Stem Cells International, Vol 2017 (2017)
The presence of highly resistant cancer cells and the toxicity to normal cells are key factors that limit chemotherapy. Here, we used two models of highly resistant lung cancer cells: (1) adherent cells growing under prolonged periods of serum starva
Externí odkaz:
https://doaj.org/article/52c76cf51f3b462ba5aac97fe25cc01c
Autor:
Juan Sebastian Yakisich, Neelam Azad, Rajkumar Venkatadri, Yogesh Kulkarni, Clayton Wright, Vivek Kaushik, Anand Krishnan V. Iyer
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Like with most solid tumors, the presence of a subpopulation of cancer stem cells (CSCs) or cancer stem-like cells (CS-LCs) has been associated with chemoresistance and tumor relapse in lung cancer cells. In the absence of serum, CSCs/CS-LCs have the
Externí odkaz:
https://doaj.org/article/b443c3d6eefd453da896d3d0750ae297
Autor:
Neelam Azad, Vivek Kaushik, Kumar Felix, Juan Sebastian Yakisich, Anand Krishnan V. Iyer, Yogesh Kulkarni
Publikováno v:
World Journal of Stem Cells
The classical cancer stem cell (CSCs) theory proposed the existence of a rare but constant subpopulation of CSCs. In this model cancer cells are organized hierarchically and are responsible for tumor resistance and tumor relapse. Thus, eliminating CS
Publikováno v:
Pharmacological Reports. 69:788-797
Background Resveratrol is a dietary compound that has been widely reported for its anticancer activities. However, successful extrapolation of its effects to pre-clinical studies is met with limited success due to inadequate bioavailability. We inves
Autor:
Vivek Kaushik, Anand Krishnan V. Iyer, Juan Sebastian Yakisich, Neelam Azad, Clayton Wright, Yon Rojanasakul, Yogesh Kulkarni, Rajkumar Venkatadri
Publikováno v:
Journal of Cellular Physiology. 232:2497-2507
Lung cancer is a leading cause of cancer-related death in the United States. Although several drugs have been developed that target individual biomarkers, their success has been limited due to intrinsic or acquired resistance for the specific targets
Publikováno v:
Journal of Cellular Physiology. 232:2280-2286
In cancer cells, the reversible nature of the stemness status in terms of chemoresistance has been poorly characterized. In this study, we have simulated one cycle of environmental conditions to study such reversibility by first generating floating t
Publikováno v:
Journal of Cellular Physiology. 232:2033-2043
The efficacy of chemotherapy is hindered by both tumor heterogeneity and acquired or intrinsic multi-drug resistance caused by the contribution of multidrug resistance proteins and stemness-associated prosurvival markers. Therefore, targeting multi-d
Publikováno v:
Stem Cells International
Stem Cells International, Vol 2017 (2017)
Stem Cells International, Vol 2017 (2017)
The presence of highly resistant cancer cells and the toxicity to normal cells are key factors that limit chemotherapy. Here, we used two models of highly resistant lung cancer cells: (1) adherent cells growing under prolonged periods of serum starva
Autor:
Neelam Azad, Vivek Kaushik, C. Woodard, Juan Sebastian Yakisich, B. Brinceanu, Anand Krishnan V. Iyer, Rajkumar Venkatadri
Publikováno v:
Journal of Thoracic Oncology. 15:S36-S37
Autor:
Leslie Ochs, Jennifer Danielson, Nina Pavuluri, Timothy M. Moore, Anand Krishnan V. Iyer, Rajender R. Aparasu, Samit Shah, Christopher Williams, Kathleen M.K. Boje, Kurt A. Wargo, Shareen Y. El-Ibiary, Jennifer D. Robinson
Publikováno v:
American journal of pharmaceutical education. 83(6)
Members from Cohort 13 of the Academic Leadership Fellows Program (ALFP) 2016-2017 were challenged to present a debate on the topic: "In Turbulent Times, Pharmacy Education Leaders Must Take Aggressive Action to Prevent Further Declines in Enrollment