Structural Conversion of Serotonin into Amyloid-like Nanoassemblies Conceptualizes an Unexplored Neurotoxicity Risk.

Autor: Prajapati KP; Biophysical and Biomaterials Research Laboratory, Room 310, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India., Mittal S; Biophysical and Biomaterials Research Laboratory, Room 310, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India., Ansari M; Biophysical and Biomaterials Research Laboratory, Room 310, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India., Mishra N; Biomolecular Self-Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India., Mahato OP; Biophysical and Biomaterials Research Laboratory, Room 310, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India., Tiku AB; Biophysical and Biomaterials Research Laboratory, Room 310, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India., Anand BG; Biomolecular Self-Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India., Kar K; Biophysical and Biomaterials Research Laboratory, Room 310, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.

Publikováno v: ACS nano [ACS Nano] 2024 Dec 17; Vol. 18 (50), pp. 34044-34062. Date of Electronic Publication: 2024 Dec 02.

Molecular insights into the phase transition of lysozyme into amyloid nanostructures: Implications of therapeutic strategies in diverse pathological conditions.

Autor: Roy S; Biomolecular Self-Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India., Srinivasan VR; Biomolecular Self-Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India., Arunagiri S; Biomolecular Self-Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India., Mishra N; Biomolecular Self-Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India., Bhatia A; Biomolecular Self-Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India., Shejale KP; Dept. of Chemical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Gyeongbuk 37673, South Korea., Prajapati KP; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India., Kar K; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.. Electronic address: karunakarkar@gmail.com., Anand BG; Biomolecular Self-Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India.. Electronic address: bibin.anand276@gmail.com.

Publikováno v: Advances in colloid and interface science [Adv Colloid Interface Sci] 2024 Sep; Vol. 331, pp. 103205. Date of Electronic Publication: 2024 May 23.

Tailoring the Molecular Structure of 6-Gingerol for Targeting the Phase Separation in Human Lysozyme.

Autor: Bonda R; Biomolecular Self-Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India., Mishra N; Biomolecular Self-Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India., Bhatia A; Biomolecular Self-Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India., Prajapati KP; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India., Acharya AY; Biomolecular Self-Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India., Manjunathan T; Department of Chemistry, SRM-Institute of Science and Technology, Kattankulathur, Chennai, 603203 Tamil Nadu, India., Gopinath P; Department of Chemistry, SRM-Institute of Science and Technology, Kattankulathur, Chennai, 603203 Tamil Nadu, India., Kar K; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India., Anand BG; Biomolecular Self-Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India.

Publikováno v: The journal of physical chemistry letters [J Phys Chem Lett] 2024 Aug 08; Vol. 15 (31), pp. 8032-8041. Date of Electronic Publication: 2024 Jul 31.

Initiation of Brain Extract Fibrillation and Effective Cellular Internalization of Tryptophan Fibrils Unveils Its Neurotoxicity Risk.

Autor: Prajapati KP; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India., Ansari M; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India., Mittal S; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India., Anand BG; Biomolecular Self-Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India., Kar K; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2023 Dec 20; Vol. 14 (24), pp. 4274-4281. Date of Electronic Publication: 2023 Nov 14.

Bioactivation of an orthodontic wire using multifunctional nanomaterials to prevent plaque accumulation.

Autor: Anand BG; Biomolecular Self Assembly Lab, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu-603203, India; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi- 110067, India. Electronic address: bibin.anand276@gmail.com., Shejale KP; Department of Chemical Engineering, Pohang University of Science and Technology, Pohang 37673, Republic of Korea., Rajesh Kumar R; School of Nanoscience and Technology, Indian Institute of Technology Kharagpur, West Bengal 721302, India., Thangam R; Dynamic Nano-Bioengineering Lab, Department of Materials Science & Engineering, Korea University, Seoul 02841, Republic of Korea., Prajapati KP; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi- 110067, India., Kar K; Biophysical and Biomaterials Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi- 110067, India., Mala R; Department of Biotechnology, Mepco Schlenk Engineering College, Sivakasi 626123, India. Electronic address: maalsindia@mepcoeng.ac.in.

Publikováno v: Biomaterials advances [Biomater Adv] 2023 May; Vol. 148, pp. 213346. Date of Electronic Publication: 2023 Feb 16.