Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anand, Minajigi"'
Autor:
Jeannie T. Lee, Yunfei Chen, Robert Morris, Myriam Boukhali, Anand Minajigi, Chia-Yu Guh, Wilhelm Haas, Hsueh-Ping Chu, Yu-Hung Hsieh
Publikováno v:
Nature Protocols. 16:3672-3694
More than 90% of the human genome is transcribed into noncoding RNAs, but their functional characterization has lagged behind. A major bottleneck in the understanding of their functions and mechanisms has been a dearth of systematic methods for ident
Autor:
Hsueh-Ping, Chu, Anand, Minajigi, Yunfei, Chen, Robert, Morris, Chia-Yu, Guh, Yu-Hung, Hsieh, Myriam, Boukhali, Wilhelm, Haas, Jeannie T, Lee
Publikováno v:
Nature protocols. 16(7)
More than 90% of the human genome is transcribed into noncoding RNAs, but their functional characterization has lagged behind. A major bottleneck in the understanding of their functions and mechanisms has been a dearth of systematic methods for ident
Autor:
Bernhard Payer, Myriam Boukhali, Hongjae Sunwoo, Jeannie T. Lee, Barry Kesner, Derek Lessing, Anand Minajigi, David Colognori, John E. Froberg, Chunyao Wei, Wilhelm Haas
Publikováno v:
Science. 349
INTRODUCTION The mammal has evolved an epigenetic mechanism to silence one of two X chromosomes in the XX female to equalize gene dosages with the XY male. Once established, the inactivated X chromosome (Xi) is extremely stable and is maintained thro
In all living systems, the fidelity of translation is maintained in part by the editing mechanisms of aminoacyl-tRNA synthetases (ARSs). Some nonproteogenic amino acids, including β-hydroxynorvaline (HNV) are nevertheless efficiently aminoacylated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e7ec49fe29425ba71810d267cfcb6e
https://europepmc.org/articles/PMC3063515/
https://europepmc.org/articles/PMC3063515/
Aminoacyl-tRNA synthetases (aaRSs) join amino acids to 1 of 2 terminal hydroxyl groups of their cognate tRNAs, thereby contributing to the overall fidelity of protein synthesis. In class II histidyl-tRNA synthetase (HisRS) the nonbridging S p -oxygen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4123b7c042eca396834fcaf0132cd3
https://europepmc.org/articles/PMC2584683/
https://europepmc.org/articles/PMC2584683/
Publikováno v:
FEBS Letters. (2):366-375
During protein synthesis, tRNA serves as the intermediary between cognate amino acids and their corresponding RNA trinucleotide codons. Aminoacyl-tRNA is also a biosynthetic precursor and amino acid donor for other macromolecules. AA-tRNAs allow tran