Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Anand, Goswami"'
Autor:
Francesco Antoniani, Marco Cimino, Laura Mediani, Jonathan Vinet, Enza M. Verde, Valentina Secco, Alfred Yamoah, Priyanka Tripathi, Eleonora Aronica, Maria E. Cicardi, Davide Trotti, Jared Sterneckert, Anand Goswami, Serena Carra
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-16 (2023)
Abstract Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are two neurodegenerative disorders that share genetic causes and pathogenic mechanisms. The critical genetic players of ALS and FTD are the TARDBP, FUS and C9orf72 genes,
Externí odkaz:
https://doaj.org/article/6a9ffd2c23cc47febd11d60c19088ee9
Autor:
Anand Goswami, Serena Carra
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 9, Pp 1875-1876 (2024)
Externí odkaz:
https://doaj.org/article/2a4bb7f204db4f258617b26ae25542f9
Autor:
Alexander Trofimov, Dmitrii Pavlov, Anand Goswami, Anna Gorlova, Kirill Chaprov, Aleksei Umriukhin, Allan Kalueff, Alexey Deykin, Klaus-Peter Lesch, Daniel Clive Anthony, Tatyana Strekalova
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 33, Iss , Pp 100686- (2023)
CNS inflammation, including microglial activation, in response to peripheral infections are known to contribute to the pathology of both familial and sporadic neurodegenerative disease. The relationship between Fused-in-Sarcoma Protein (FUS)-mediated
Externí odkaz:
https://doaj.org/article/80e012cd55704c19bdc25c3f316432fc
Autor:
Priyanka Tripathi, Haihong Guo, Alice Dreser, Alfred Yamoah, Antonio Sechi, Christopher Marvin Jesse, Istvan Katona, Panagiotis Doukas, Stefan Nikolin, Sabrina Ernst, Eleonora Aronica, Hannes Glaß, Andreas Hermann, Harry Steinbusch, Alfred C. Feller, Markus Bergmann, Dick Jaarsma, Joachim Weis, Anand Goswami
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-18 (2021)
Abstract Mutations in RNA binding proteins (RBPs) and in genes regulating autophagy are frequent causes of familial amyotrophic lateral sclerosis (fALS). The P56S mutation in vesicle-associated membrane protein-associated protein B (VAPB) leads to fA
Externí odkaz:
https://doaj.org/article/9f78736de9224ba390eaa5a395c2084f
Autor:
Alfred Yamoah, Priyanka Tripathi, Haihong Guo, Leonie Scheve, Peter Walter, Sandra Johnen, Frank Müller, Joachim Weis, Anand Goswami
Publikováno v:
Cells, Vol 12, Iss 7, p 1094 (2023)
The retinal degeneration 10 (rd10) mouse model is widely used to study retinitis pigmentosa (RP) pathomechanisms. It offers a rather unique opportunity to study trans-neuronal degeneration because the cell populations in question are separated anatom
Externí odkaz:
https://doaj.org/article/43f65bd4a4144cb6b5183462d6a76708
Autor:
Marcel Naumann, Kevin Peikert, Rene Günther, Anneke J. van derKooi, Eleonora Aronica, Annemarie Hübers, Veronique Danel, Philippe Corcia, Francisco Pan‐Montojo, Sebahattin Cirak, Göknur Haliloglu, Albert C. Ludolph, Anand Goswami, Peter M. Andersen, Johannes Prudlo, Florian Wegner, Philip Van Damme, Jochen H. Weishaupt, Andreas Hermann
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 12, Pp 2384-2394 (2019)
Abstract Objective Mutations in Fused in Sarcoma (FUS or TLS) are the fourth most prevalent in Western European familial amyotrophic lateral sclerosis (ALS) populations and have been associated with causing both early and very late disease onset. FUS
Externí odkaz:
https://doaj.org/article/29d3f763bcef4f7cab2c7d82907db880
Autor:
Marcel Naumann, Arun Pal, Anand Goswami, Xenia Lojewski, Julia Japtok, Anne Vehlow, Maximilian Naujock, René Günther, Mengmeng Jin, Nancy Stanslowsky, Peter Reinhardt, Jared Sterneckert, Marie Frickenhaus, Francisco Pan-Montojo, Erik Storkebaum, Ina Poser, Axel Freischmidt, Jochen H. Weishaupt, Karlheinz Holzmann, Dirk Troost, Albert C. Ludolph, Tobias M. Boeckers, Stefan Liebau, Susanne Petri, Nils Cordes, Anthony A. Hyman, Florian Wegner, Stephan W. Grill, Joachim Weis, Alexander Storch, Andreas Hermann
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Abnormal cytoplasmic aggregates of FUS are a hallmark of some forms of amyotrophic lateral sclerosis (ALS). Here, using neurons derived from patients with FUS-ALS, the authors demonstrate that impairment of PARP-dependent DNA damage signaling is an e
Externí odkaz:
https://doaj.org/article/421d7fe19126448d9734fe819843c747
Abl kinase-mediated FUS Tyr526 phosphorylation alters nucleocytoplasmic FUS localization in FTLD-FUS
Autor:
Helena Motaln, Urša Čerček, Alfred Yamoah, Priyanka Tripathi, Eleonora Aronica, Anand Goswami, Boris Rogelj
Publikováno v:
Brain.
Nuclear to cytoplasmic mislocalization and aggregation of multiple RNA-binding proteins (RBPs), including Fused in sarcoma (FUS), are the main neuropathological features of the majority of cases of amyotrophic lateral sclerosis (ALS) and frontotempor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fea40063d25d11540aa3e3e286a063e5
https://doi.org/10.1093/brain/awad130
https://doi.org/10.1093/brain/awad130
Autor:
Anand Goswami, Alfred Yamoah, Priyanka Tripathi, Haihong Guo, Leoni Scheive, Peter Walter, Sandra Johnen, Frank Müller, Joachim Weis
The retinal degeneration 10 (rd10) mouse model is widely used to study retinitis pigmentosa (RP) pathomechanisms. It offers a rather unique opportunity to study trans-neuronal degeneration because the cell populations in question are separated anatom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb5fcf07e6f3e450d2644a3c536a6693
https://doi.org/10.21203/rs.3.rs-1937402/v1
https://doi.org/10.21203/rs.3.rs-1937402/v1
Autor:
Anika M. Helferich, Peter M. Andersen, Priyanka Tripathi, Vitaly Zimyanin, Sarah J Brockmann, Axel Freischmidt, Albert C. Ludolph, Hannes Glaß, Joachim Weis, Eleonora Aronica, Andreas Hermann, Peter J. Oefner, Karin M Danzer, Maria Demestre, Karlheinz Holzmann, Alfred Yamoah, Anand Goswami, Tobias M. Böckers, Jörg Reinders, Jochen H. Weishaupt, Katharina Limm, Ina Poser
Publikováno v:
Brain
Brain 144(4), 1214-1229 (2021). doi:10.1093/brain/awab018
Brain, 144(4), 1214-1229. Oxford University Press
Brain 144(4), 1214-1229 (2021). doi:10.1093/brain/awab018
Brain, 144(4), 1214-1229. Oxford University Press
Knowledge about converging disease mechanisms in the heterogeneous syndrome amyotrophic lateral sclerosis (ALS) is rare, but may lead to therapies effective in most ALS cases. Previously, we identified serum microRNAs downregulated in familial ALS, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691c4d51f5ea8d795f65a3e3483b9bef
https://doi.org/10.1093/brain/awab018
https://doi.org/10.1093/brain/awab018