Výsledky vyhledávání

Akademický článek

P351: PROTEASOME INHIBITORS INDUCE DNA DAMAGE AND MITOTIC CATASTROPHE IN ACUTE LYMPHOBLASTIC LEUKAEMIA (ALL) VIA AUTOPHAGY-MEDIATED DEGRADATION OF WEE1

Autor: Chun Fung Sin, Rahman Ud Din, Anan Jiao, Kei-Ching Yuen

Publikováno v: HemaSphere, Vol 7, p e09566f7 (2023)

Externí odkaz: https://doaj.org/article/41d60fdf73b146fb9071da0b2ab00789

Zobrazit plný text záznamu

Homoharringtonine Is Effective in Treating T-ALL By Downregulating MCL-1 with Synergistic Effect When Combining with Venetoclax

Autor: Sin Chun-Fung, Anan Jiao, Kei-ching Yuen, Rahman Ud Din, On Yi, Phoebe Wong

Publikováno v: Blood. 140:11554-11556

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb9da612950ec86e50784ce9fe4d6b15
https://doi.org/10.1182/blood-2022-165941

Zobrazit plný text záznamu

Abstract 6199: Proteasome inhibitors induce DNA damage and mitotic catastrophe in acute lymphoblastic leukemia via autophagy-mediated degradation of WEE1

Autor: Chun-fung Sin, Rahman Ud Din, Anan Jiao, Kei-ching Yuen

Publikováno v: Cancer Research. 83:6199-6199

Acute lymphoblastic leukemia (ALL) is an aggressive hematolymphoid malignancy and the prognosis is poor in adults with long-term survival of only 30% due to the high prevalence of high-risk subtypes. Therefore, there is an urgent need to develop nove

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0cb41b42a4e1a2747e8b611c9d9f8073
https://doi.org/10.1158/1538-7445.am2023-6199

Zobrazit plný text záznamu

Abstract 1574: Homoharringtonine is effective in treating acute lymphoblastic leukaemia via modulation of apoptotic pathway

Autor: Anan Jiao, Kei Ching Yuen, Rahman Ud DIN, On Yi Phoebe Wong, Sin Chun-Fung

Publikováno v: Cancer Research. 83:1574-1574

Acute lymphoblastic leukaemia (ALL) is an aggressive and highly lethal malignancy caused by clonal mutations in lymphoid progenitor cells. The prognosis for adult ALL remains poor, with only 30-40% of adult patients achieving long-term remission. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba1f4c5ec640e053db3f682c2a5d404d
https://doi.org/10.1158/1538-7445.am2023-1574

Zobrazit plný text záznamu

Bortezomib Is Effective in Treating T-ALL, Inducting G2/M Cell Cycle Arrest and WEE1 Downregulation

Autor: Timothy Ming-Hun Wan, Sin Chun-fung, Aarmann Anil Mohinani Mohan, Anan Jiao, Yinxia Qiu

Publikováno v: Blood. 138:4360-4360

T lymphoblastic leukaemia (T-ALL) is an aggressive haematological malignancy with poor outcome, especially for relapse/refractory disease. Early T- cell precursor acute lymphoblastic leukaemia (ETP-ALL) is a recently identified subtype of T-ALL with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa870d291f0f330df294b3fc91c37456
https://doi.org/10.1182/blood-2021-149455

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání