Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anamarija Pfeiffer"'
Autor:
Anna-Kathrine Pedersen, Anamarija Pfeiffer, Gopal Karemore, Vyacheslav Akimov, Dorte B. Bekker-Jensen, Blagoy Blagoev, Chiara Francavilla, Jesper V. Olsen
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102321- (2021)
Summary: Neuroblastoma is a highly heterogeneous embryonal solid tumor of the sympathetic nervous system. As some tumors can be treated to undergo differentiation, investigating this process can guide differentiation-based therapies of neuroblastoma.
Externí odkaz:
https://doaj.org/article/5501645317bc4f13a024b87b28776561
Autor:
Vidyasiri Vemulapalli, Lily A Chylek, Alison Erickson, Anamarija Pfeiffer, Khal-Hentz Gabriel, Jonathan LaRochelle, Kartik Subramanian, Ruili Cao, Kimberley Stegmaier, Morvarid Mohseni, Matthew J LaMarche, Michael G Acker, Peter K Sorger, Steven P Gygi, Stephen C Blacklow
Publikováno v:
eLife, Vol 10 (2021)
SHP2 is a protein tyrosine phosphatase that normally potentiates intracellular signaling by growth factors, antigen receptors, and some cytokines, yet is frequently mutated in human cancer. Here, we examine the role of SHP2 in the responses of breast
Externí odkaz:
https://doaj.org/article/653eeb5ad6e5454e9488ec62514b8bc7
Autor:
Tanveer S. Batth, Moreno Papetti, Anamarija Pfeiffer, Maxim A.X. Tollenaere, Chiara Francavilla, Jesper V. Olsen
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2784-2796 (2018)
Summary: Despite its low cellular abundance, phosphotyrosine (pTyr) regulates numerous cell signaling pathways in health and disease. We applied comprehensive phosphoproteomics to unravel differential regulators of receptor tyrosine kinase (RTK)-init
Externí odkaz:
https://doaj.org/article/f690d33ca66c4ee0aed10d6c43b99a3d
Autor:
Jesper V. Olsen, Lars J. Jensen, Kim Theilgaard-Mönch, Stephen C. Blacklow, Vidyasiri Vemulapalli, Kristian Reckzeh, Ilaria Piga, Marie Locard-Paulet, Giulia Franciosa, Anamarija Pfeiffer
Supplementary Data from Phosphorylation of SHP2 at Tyr62 Enables Acquired Resistance to SHP2 Allosteric Inhibitors in FLT3-ITD–Driven AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e44e4fc3515e4df0e347ed1a54c643c
https://doi.org/10.1158/0008-5472.22430284
https://doi.org/10.1158/0008-5472.22430284
Autor:
Jesper V. Olsen, Lars J. Jensen, Kim Theilgaard-Mönch, Stephen C. Blacklow, Vidyasiri Vemulapalli, Kristian Reckzeh, Ilaria Piga, Marie Locard-Paulet, Giulia Franciosa, Anamarija Pfeiffer
The protein tyrosine phosphatase SHP2 is crucial for oncogenic transformation of acute myeloid leukemia (AML) cells expressing mutated receptor tyrosine kinases. SHP2 is required for full RAS-ERK activation to promote cell proliferation and survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78e5a2bf99c8efb8cfecfca5df859849
https://doi.org/10.1158/0008-5472.c.6513577.v1
https://doi.org/10.1158/0008-5472.c.6513577.v1
Autor:
Jesper V. Olsen, Lars J. Jensen, Kim Theilgaard-Mönch, Stephen C. Blacklow, Vidyasiri Vemulapalli, Kristian Reckzeh, Ilaria Piga, Marie Locard-Paulet, Giulia Franciosa, Anamarija Pfeiffer
Supplementary Table from Phosphorylation of SHP2 at Tyr62 Enables Acquired Resistance to SHP2 Allosteric Inhibitors in FLT3-ITD–Driven AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3670270ef0f89fb2bad014be2a715886
https://doi.org/10.1158/0008-5472.22430254.v1
https://doi.org/10.1158/0008-5472.22430254.v1
Autor:
Jesper V. Olsen, Lars J. Jensen, Kim Theilgaard-Mönch, Stephen C. Blacklow, Vidyasiri Vemulapalli, Kristian Reckzeh, Ilaria Piga, Marie Locard-Paulet, Giulia Franciosa, Anamarija Pfeiffer
Supplementary Figure from Phosphorylation of SHP2 at Tyr62 Enables Acquired Resistance to SHP2 Allosteric Inhibitors in FLT3-ITD–Driven AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a286fc679490997ba56e2737835e74
https://doi.org/10.1158/0008-5472.22430278
https://doi.org/10.1158/0008-5472.22430278
Autor:
Anamarija Pfeiffer, Giulia Franciosa, Marie Locard-Paulet, Ilaria Piga, Kristian Reckzeh, Vidyasiri Vemulapalli, Stephen C. Blacklow, Kim Theilgaard-Mönch, Lars J. Jensen, Jesper V. Olsen
Publikováno v:
Cancer Res
Pfeiffer, A, Franciosa, G, Locard-Paulet, M, Piga, I, Reckzeh, K, Vemulapalli, V, Blacklow, S C, Theilgaard-Mönch, K, Jensen, L J & Olsen, J V 2022, ' Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML ', Cancer Research, vol. 82, no. 11, pp. 2141-2155 . https://doi.org/10.1158/0008-5472.CAN-21-0548
Pfeiffer, A, Franciosa, G, Locard-Paulet, M, Piga, I, Reckzeh, K, Vemulapalli, V, Blacklow, S C, Theilgaard-Mönch, K, Jensen, L J & Olsen, J V 2022, ' Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML ', Cancer Research, vol. 82, no. 11, pp. 2141-2155 . https://doi.org/10.1158/0008-5472.CAN-21-0548
The protein tyrosine phosphatase SHP2 is crucial for oncogenic transformation of acute myeloid leukemia (AML) cells expressing mutated receptor tyrosine kinases. SHP2 is required for full RAS-ERK activation to promote cell proliferation and survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70518e71a8b0f7bfae33510da42823f
https://europepmc.org/articles/PMC9177641/
https://europepmc.org/articles/PMC9177641/
Autor:
Anamarija Pfeiffer, Steven P. Gygi, Michael G. Acker, Jonathan R. LaRochelle, Stephen C. Blacklow, Kartik Subramanian, Lily A. Chylek, Vidyasiri Vemulapalli, Alison R. Erickson, Ruili Cao, Kimberley Stegmaier, Khal-Hentz Gabriel, Matthew J. LaMarche, Peter K. Sorger, Morvarid Mohseni
Publikováno v:
Vemulapalli, V, Chylek, L A, Erickson, A, Pfeiffer, A, Gabriel, K H, Larochelle, J, Subramanian, K, Cao, R, Stegmaier, K, Mohseni, M, Lamarche, M J, Acker, M G, Sorger, P K, Gygi, S P & Blacklow, S C 2021, ' Time resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of shp2-dependent signaling ', eLife, vol. 10, e64251 . https://doi.org/10.7554/eLife.64251
eLife, Vol 10 (2021)
eLife
eLife, Vol 10 (2021)
eLife
SHP2 is a protein tyrosine phosphatase that normally potentiates intracellular signaling by growth factors, antigen receptors, and some cytokines, yet is frequently mutated in human cancer. Here, we examine the role of SHP2 in the responses of breast
Autor:
Lily A. Chylek, Khal-Hentz Gabriel, Kartik Subramanian, Kimberley Stegmaier, Vidyasiri Vemulapalli, Matthew J. LaMarche, Jonathan R. LaRochelle, Michael G. Acker, Peter K. Sorger, Stephen C. Blacklow, Alison R. Erickson, Steven P. Gygi, Ruili Cao, Anamarija Pfeiffer, Morvarid Mohseni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df87f7af9d99845bffe30ee9bd0ee0b0
https://doi.org/10.7554/elife.64251.sa2
https://doi.org/10.7554/elife.64251.sa2