Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Anam Qudrat"'
Publikováno v:
Integrative Biology. 10:166-173
As monoclonal antibodies have two epitopes for their target ligand, they should theoretically dimerize target receptors upon binding. In particular, the dimerization of the vascular endothelial growth factor (VEGF) receptor 2 (VEGFR2) stimulates earl
Autor:
Kevin Truong, Anam Qudrat
Publikováno v:
ACS Synthetic Biology. 7:531-539
The Ca2+ signaling toolkit is the set of proteins used by living systems to generate and respond to Ca2+ signals. The selective expression of these proteins in particular tissues, cell types and subcellular locations allows the Ca2+ signal to regulat
Autor:
Kevin Truong, Anam Qudrat
Publikováno v:
ACS Synthetic Biology. 6:1563-1571
Inflammatory lesions, often seen in diseases such as rheumatoid arthritis, atherosclerosis and cancer, feature an acidic (i.e., low pH) microenvironment rampant with cytokines, such as CSF1. For potential therapeutic intervention targeted at these CS
Autor:
Kevin Truong, Anam Qudrat
Publikováno v:
ACS Synthetic Biology. 6:582-590
The versatility of Ca2+ signals allows it to regulate diverse cellular processes such as migration, apoptosis, motility and exocytosis. In some receptors (e.g., VEGFR2), Ca2+ signals are generated upon binding their ligand(s) (e.g., VEGF-A). Here, we
Publikováno v:
Integrative biology : quantitative biosciences from nano to macro. 10(3)
As monoclonal antibodies have two epitopes for their target ligand, they should theoretically dimerize target receptors upon binding. In particular, the dimerization of the vascular endothelial growth factor (VEGF) receptor 2 (VEGFR2) stimulates earl
Publikováno v:
Molecular Basis and Emerging Strategies for Anti-aging Interventions ISBN: 9789811316982
Aging brings about many risks factors that can lead to age-related chronic disorders such as atherosclerosis, osteoporosis, and neurodegenerative diseases. Implicated in aging and age-related pathologies, the accumulation of senescent cells can preve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f8a151fa5881927111460a49d5770cc
https://doi.org/10.1007/978-981-13-1699-9_5
https://doi.org/10.1007/978-981-13-1699-9_5
Autor:
Anam, Qudrat, Kevin, Truong
Publikováno v:
ACS synthetic biology. 7(2)
The Ca
Autor:
Anam, Qudrat, Kevin, Truong
Publikováno v:
ACS synthetic biology. 6(3)
The versatility of Ca
Autor:
Anam Qudrat, Kevin Truong
Publikováno v:
BMC Biotechnology
Background To achieve synthetic control over how a cell responds to other cells or the extracellular environment, it is important to reliably engineer proteins that can traffic and span the plasma membrane. Using a modular approach to assemble protei
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1495
Protein trans-splicing is a posttranslational modification that joins two protein fragments together via a peptide a bond in a process that does not require exogenous cofactors. Towards achieving cellular control, synthetically engineered systems hav