Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Analytical treatment interruptions"'
Autor:
Karine Dubé, Thomas J. Villa, William Freshwater, Brittney Mauk, Annette Rid, Michael J. Peluso
Publikováno v:
Journal of Virus Eradication, Vol 10, Iss 3, Pp 100386- (2024)
Analytical treatment interruptions (ATIs) are widely used to evaluate HIV cure-related research interventions. However, sex partners of cure-related trial participants might be at risk of acquiring HIV during ATIs. Addressing this risk is key to ensu
Externí odkaz:
https://doaj.org/article/1f25c5f4b2ae45d09f5d26a33c64961a
Publikováno v:
HIV Research & Clinical Practice, Vol 25, Iss 1 (2024)
Background There is limited systematic information available about the perspectives of participants enrolled in intensive combination HIV cure-related trials inclusive of an extended analytical treatment interruption (ATI). Objective To assess and un
Externí odkaz:
https://doaj.org/article/a6422f2af70e4932834bd92cd9335ea5
Autor:
Andrea Bilger, Eion Plenn, Frances K. Barg, Katharine A. Rendle, William B. Carter, Andrea Lamour-Harrington, Nora Jones, Beth Peterson, John A. Sauceda, Pablo Tebas, Karam Mounzer, David Metzger, Luis J. Montaner, Karine Dubé
Publikováno v:
HIV Research & Clinical Practice, Vol 24, Iss 1 (2023)
Background A feature of HIV cure trials is the need to interrupt treatment to test the efficacy of experimental interventions—a process known as analytical treatment interruptions (ATIs). Objectives We report the experiences of participants after t
Externí odkaz:
https://doaj.org/article/c8680ade81e141539c7c29e476a65d43
Autor:
Karine Dubé, Harsh Agarwal, William B. Carter, Lynda Dee, Jeff Taylor, Christopher Roebuck, Beth Peterson, Hursch Patel, Samuel Ndukwe, Kenneth M. Lynn, Linden Lalley-Chareczko, Emily Hiserodt, Sukyung Kim, Daniel Rosenbloom, Brad R. Evans, Melanie Anderson, Daria J. Hazuda, Kevin Bateman, Bonnie J. Howell, Livio Azzoni, Karam Mounzer, Pablo Tebas, Luis J. Montaner
Publikováno v:
HIV Research & Clinical Practice, Vol 23, Iss 1, Pp 76-90 (2022)
Background: HIV cure-directed clinical trials using analytical treatment interruptions (ATIs) require participants to adhere to frequent monitoring visits for viral load tests. Novel viral load monitoring strategies are needed to decrease participant
Externí odkaz:
https://doaj.org/article/05fbd233a40d4f83afda13ea5699851d
Autor:
Karine Dubé, Deli Mthimkhulu, Wiseman Ngcobo, Deborah Mindry, Luyanda Maphalala, Vanessa Pillay, Whitney Tran, Ana Korolkova, Thumbi Ndung’u, Krista Dong
Publikováno v:
HIV Research & Clinical Practice, Vol 24, Iss 1 (2023)
Background Developing a cure for HIV remains a global scientific priority. In 2022, the Females Rising through Education, Support and Health (FRESH) cohort launched an HIV cure-related trial involving an analytical treatment interruption (ATI) in Dur
Externí odkaz:
https://doaj.org/article/ea969ceba76b4f8eb9b387c666b0c791
Akademický článek
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Akademický článek
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Publikováno v:
HIV Research & Clinical Practice, Vol 23, Iss 1, Pp 61-75 (2022)
Background: Research on stakeholder perspectives of HIV cure research has involved people with HIV (PWH), who generally cite the importance of HIV clinician advice in making decisions about trial participation. However, there has been little explorat
Externí odkaz:
https://doaj.org/article/912e814585a349f1a1221d4618e6b404
Autor:
Danielle M. Campbell, Karine Dubé, Portia D. Cowlings, Patricia Dionicio, Rowena M. Tam, Harsh Agarwal, Jamila K. Stockman, Judith D. Auerbach, John A. Sauceda, Amy A. Conroy, Mallory O. Johnson
Publikováno v:
BMC Public Health, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Most HIV cure-related studies involve interrupting antiretroviral treatment to assess the efficacy of pharmacologic interventions – also known as analytical treatment interruptions (ATIs). ATIs imply the risk of passing HIV to s
Externí odkaz:
https://doaj.org/article/87db71fcbe1f45ad81dbfc8d66817e8b
Autor:
Karine Dubé, John Kanazawa, Christopher Roebuck, Steven Johnson, William B. Carter, Lynda Dee, Beth Peterson, Kenneth M. Lynn, Linden Lalley-Chareczko, Emily Hiserodt, Sukyung Kim, Daniel Rosenbloom, Brad R. Evans, Melanie Anderson, Daria J. Hazuda, Lisa Shipley, Kevin Bateman, Bonnie J. Howell, Karam Mounzer, Pablo Tebas, Luis J. Montaner
Publikováno v:
HIV Research & Clinical Practice, Vol 23, Iss 1, Pp 120-135 (2022)
Background People with HIV (PWH) and community members have advocated for the development of a home-based viral load test device that could make analytical treatment interruptions (ATIs) less burdensome. Objective We assessed community acceptability
Externí odkaz:
https://doaj.org/article/d5f0d32e8dbc42dd958bb6aeb88bedaa