Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Analiese R. Fernandes"'
Autor:
Lindsay A. Welikovitch, Simon Dujardin, Amy R. Dunn, Analiese R. Fernandes, Anita Khasnavis, Lori B. Chibnik, Catherine C. Kaczorowski, Bradley T. Hyman
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105983- (2023)
Summary: The speed and scope of cognitive deterioration in Alzheimer's disease is highly associated with the advancement of tau neurofibrillary lesions across brain networks. We tested whether the rate of tau propagation is a heritable disease trait
Externí odkaz:
https://doaj.org/article/8b321675abc14004a7beb47a24a7e94f
Autor:
Bradley T. Hyman, Anastasie Maté de Gérando, Simon Dujardin, Matthew P. Frosch, Analiese R. Fernandes
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 80:912-921
The protein tau, when misfolded in neurodegenerative diseases, has several prion-like properties including being able to spread by cell-to-cell transfer, induce templated seeding, and exist in distinct conformational strains. These properties of tran
Autor:
Caitlin Commins, Bradley T. Hyman, Naomi Klickstein, Matthew P. Frosch, Simon Dujardin, Tarun V. Kamath, Analiese R. Fernandes, Derek H. Oakley
Publikováno v:
Brain Communications
The accumulation of tau aggregates throughout the human brain is the hallmark of a number of neurodegenerative conditions classified as tauopathies. Increasing evidence shows that tau aggregation occurs in a ‘prion-like’ manner, in which a small
Autor:
Riley N. Bannon, Tarun V. Kamath, Simon Dujardin, Bradley T. Hyman, Analiese R. Fernandes, Mark B. De Los Santos, Caitlin Commins
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Miwei Hu, Marta Perez-Rando, Bradley T. Hyman, Ashley B. Robbins, Analiese R. Fernandes, Tarun V. Kamath, Rachel E. Bennett, Simon Dujardin
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-16 (2020)
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-16 (2020)
Microangiopathy, including proliferation of small diameter capillaries, increasing vessel tortuosity, and increased capillary blockage by leukocytes, was previously observed in the aged rTg4510 mouse model. Similar gene expression changes related to
Autor:
Judith A. Steen, Dinorah Jean-Gilles, Pieter Beerepoot, Naomi Klickstein, Bradley T. Hyman, Mark B. De Los Santos, Tarun V. Kamath, Renee Moore, Arthur Viode, Aurélien Lathuilière, Lori B. Chibnik, Matthew P. Frosch, Ryan C. Clark, Derek H. Oakley, Alberto Serrano-Pozo, Benjamin D. Moore, Fiona Elwood, Rudolph E. Tanzi, Diana L. Corjuc, Simon Dujardin, Analiese R. Fernandes, Matthew E. Kennedy, Patrick M. Dooley, Bianca T. Corjuc, Kristina Mullin, Caitlin Commins, Kevin Atchison
Publikováno v:
Nat Med
Nature medicine, Vol. 26, No 8 (2020) pp. 1256-1263
Nature medicine, Vol. 26, No 8 (2020) pp. 1256-1263
Alzheimer's disease (AD) causes unrelenting, progressive cognitive impairments, but its course is heterogeneous, with a broad range of rates of cognitive decline1. The spread of tau aggregates (neurofibrillary tangles) across the cerebral cortex para
Autor:
Lori B. Chibnik, Benjamin D. Moore, Arthur Viode, Fiona Elwood, Tarun V. Kamath, Renee Moore, Patrick M. Dooley, Derek H. Oakley, Dinorah Jean-Gilles, Pieter Beerepoot, Alberto Serrano-Pozo, Diana L. Corjuc, Naomi Klickstein, Bradley T. Hyman, Kevin Atchison, Mark B. De Los Santos, Matthew P. Frosch, Aurélien Lathuilière, Judith A. Steen, Kristina Mullin, Analiese R. Fernandes, Matthew E. Kennedy, Caitlin Commins, Rudolph E. Tanzi, Simon Dujardin, Ryan C. Clark, Bianca T. Corjuc
Publikováno v:
Nature Medicine. 27:356-356