Zobrazeno 1 - 10
of 4 074
pro vyhledávání: '"Analgesic Activity"'
Autor:
M. V. Pugachev, N. V. Shtyrlin, M. N. Agafonova, O. S. Vasileva, E. M. Fafanova, Y. G. Shtyrlin
Publikováno v:
Учёные записки Казанского университета: Серия Естественные науки, Vol 166, Iss 4, Pp 608-622 (2024)
Prodrug bipharmacophore anti-inflammatory compounds based on pyridoxine and ketorolac were synthesized. A new laboratory method was developed to achieve > 98 % purity of these compounds, without the use of column chromatography. Compared to ketorolac
Externí odkaz:
https://doaj.org/article/d4e8bcf6261143a098b5043eb54f0103
Autor:
Gulam Muheyuddeen, Mohd Yaqub Khan, Tanzeem Ahmad, Shriyansh Srivastava, Stuti Verma, Mo. Suheb Ansari, Nilanchala Sahu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Imidazole moieties exhibit a broad range of biological activities, including analgesic, anti-depressant, anticancer, anti-fungal, anti-tubercular, anti-inflammatory, antimicrobial, antiviral, and antifungal properties. In this study, we expl
Externí odkaz:
https://doaj.org/article/6c4a424864594843a30a66dac9706cc6
Autor:
Mohamed El fadili, Mohammed Er-rajy, Somdutt Mujwar, Abduljelil Ajala, Rachid Bouzammit, Mohammed Kara, Hatem A. Abuelizz, Sara Er-rahmani, Menana Elhallaoui
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-22 (2024)
Abstract Based on a structural family of thirty-two NR2B-selective N-Methyl-D-Aspartate receptor (NMDAR) antagonists, two phenylpiperazine derivatives labeled C37 and C39 were conceived thanks to molecular modeling techniques, as novel NMDAR inhibito
Externí odkaz:
https://doaj.org/article/68b2ece01da4488b885bf6c3bc083b71
Autor:
Ahsan Ali Khan, Muhammad Haris, Sobia Haris, Farah Deeba, Mashal Tamsil, Tayaba Basharat, Muhammad Jehangir Khan
Publikováno v:
Proceedings, Vol 38, Iss 3 (2024)
Introduction: Chalcones, are a group of organic compounds containing two aromatic rings bridged by a three-carbon -a, ?; unsaturated carbonyl system. This attracted much attention because of their versatility in pharmacological profiles. Aims & O
Externí odkaz:
https://doaj.org/article/0a85d08560014c5682e405f884ea21b7
Autor:
Thanh Mai Phuong, Trang Tran Thi Thu, Khanh Do Thi Hong, Ngoc Tran Thi Hong, Dat Tran Tien, Trang Nguyen Thi Mai, Minh Phan Hong
Publikováno v:
Vietnam Journal of Science, Technology and Engineering, Vol 66, Iss 3 (2024)
This research evaluates subchronic toxicities and analgesic effects of Stephania tetrandra S. Moore (S. tetrandra) liquid extract through oral administration in experimental animals. Over 4 weeks of subchronic toxicity research, S. tetrandra was admi
Externí odkaz:
https://doaj.org/article/99180ac622be4d96bde740814b0e3354
Autor:
Mehmet Yilmaz, Bahadir Suleyman, Renad Mammadov, Durdu Altuner, Taha Abdulkadir Coban, Seval Bulut, Halis Suleyman, Resid Coskun
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 81, Iss 1, Pp 135-143 (2024)
The aim of the study was to investigate the effects of lacidipine, amlodipine and benidipine on the analgesic activity and toxicity of tramadol. Rats (n=6/each group) were divided into five groups as control(CG), tramadol(TRD), lacidipine+tramadol(LT
Externí odkaz:
https://doaj.org/article/a0de3c9171454b4d99104c0de52ca2cf
Autor:
Zouhri Aziz, Bouddine Toufik, Menyiy Naoual El, El-Mernissi Yahya, Laaroussi Hassan, Chebaibi Mohamed, Amhamdi Hassan, Elharrak Abdelhay, Nafidi Hiba-Allah, Sitotaw Baye, Jardan Yousef A. Bin, Bourhia Mohammed, Hajji Lhoussain
Publikováno v:
Acta Pharmaceutica, Vol 74, Iss 1, Pp 81-99 (2024)
This study aims to assess the chemical composition of the aqueous extract of Cistus albidus L. leaves, as well as the potential of aqueous and hydroethanol extracts of the leaves and seeds as analgesic, anti--inflammatory, and antioxidant agents. The
Externí odkaz:
https://doaj.org/article/1e628ab45b964ef997db592bcde35081
Autor:
Pavel A. Galenko-Yaroshevsky, Olga V. Shelemekh, Viktor L. Popkov, Andrey V. Zadorozhniy, Irina B. Nektarevskaya, Natalia D. Bunyatyan, Roman A. Murashko, Svetlana A. Lebedeva, Anait V. Zelenskaya, Aleksandr V. Uvarov, Olga N. Gulevskaya, Lusine O. Alukhanyan, Tereza R. Glechyan, Alina V. Sergeeva, Alina V. Kornetskaya, Nikolay E. Korovaykin
Publikováno v:
Research Results in Pharmacology, Vol 10, Iss 1, Pp 23-43 (2024)
Introduction: Although nonsteroidal anti-inflammatory drugs (NSAIDs) have a clear therapeutic benefit, they can also have serious side effects. The most serious of these is the ulcerogenic effect, which can result in a decline in the quality of life
Externí odkaz:
https://doaj.org/article/20e84e18beac4a2cb8b2e31e37c12aaf
Autor:
Anna Rapacz, Marcin Jakubiec, Michał Abram, Jakub Jasiński, Karolina Chrzan, Małgorzata Góra, Anna Dziubina, Katarzyna Wójcik-Pszczoła, Paulina Koczurkiewicz-Adamczyk, Katarzyna Ciepiela, Elżbieta Pękala, Jolanta Obniska, Krzysztof Kamiński
Publikováno v:
Pharmaceuticals, Vol 17, Iss 11, p 1532 (2024)
Background/Objectives: To address the unmet clinical needs in the treatment of epilepsy and pain, the continued development of more effective and safer anticonvulsants and analgesics is still necessary. Therefore, herein we report synthesis and antis
Externí odkaz:
https://doaj.org/article/a251ba8d7a9a4016a31cb678d9a9dcad
Autor:
Md S. ALAM, Bassam R. RAJHI, Mohammad F. ALAM, Malik M. HAMZI, Mohammed ALBRATTY, Hassan A. ALHAZMI, Asim NAJMI, Khalid ZOGHEBI, Zia ur REHMAN, Sivakumar S. MONI
Publikováno v:
Notulae Botanicae Horti Agrobotanici Cluj-Napoca, Vol 52, Iss 2 (2024)
Traditional healers have used the shrub Calotropis procera (CP) for many years for various therapies. The present study investigated the bioactive constituents of ethanolic extract of CP leaf and dried latex using gas chromatography-mass spectrometry
Externí odkaz:
https://doaj.org/article/4caae953e2d049f0962175644d40e0d3