Výsledky vyhledávání - "Anal and Rectal Disorders"

Sex-dependent development of Kras-induced anal squamous cell carcinoma in mice

Autor: Anne E. Turco, Oline K. Rønnekleiv, Manabu Nukaya, Sean M. Ronnekleiv-Kelly, Morgan T. Walcheck, Simon Blaine-Sauer, Jessica Noel, Kristina A. Matkowskyj

Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 11, p e0259245 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)

Anal squamous cell carcinoma (SCC) will be diagnosed in an estimated 9,080 adults in the United States this year, and rates have been rising over the last several decades. Most people that develop anal SCC have associated human papillomavirus (HPV) i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984fa99e9bd4862f3c9b30423e7f3ee2
https://pubmed.ncbi.nlm.nih.gov/34735515

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Use of advanced PET-volume metrics predicts risk of local recurrence and overall survival in anal cancer

Autor: Mekhail Anwar, Matthew S. Susko, Spencer C. Behr, Tom Hope, Katherine Van Loon, Ann A. Lazar, Chia-Ching Jackie Wang, Mary Feng

Publikováno v: PloS one, vol 16, iss 2
PLoS ONE, Vol 16, Iss 2, p e0246535 (2021)
PLoS ONE

Objective Anal cancer is an uncommon malignancy with the primary treatment for localized disease being concurrent radiation and chemotherapy. Pre-treatment PET/CT is useful for target delineation, with minimal exploration of its use in prognosticatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a9bef22022eb56c0ff8a5b825532b1
https://escholarship.org/uc/item/9np1r5p0

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Self-collected and clinician-collected anal swabs show modest agreement for HPV genotyping

Autor: Racheal S. Dube Mandishora, Joel M. Palefsky, Megan B. Fitzpatrick, Trine B. Rounge, Zvavahera M. Chirenje, Babill Stray-Pedersen, Irene Kraus Christiansen, Massimo Tommasino, Sonja Lagström, Ole Herman Ambur

Publikováno v: PloS one, vol 16, iss 4
PLoS ONE, Vol 16, Iss 4, p e0250426 (2021)
e0250426
PLOS ONE
PLoS ONE

Background & aimWomen with HIV/HPV coinfection and cervical lesions are at increased risk of developing HPV related anal cancer. Self-collection of anal swabs may facilitate HPV molecular testing in anal cancer screening, especially in high-risk grou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70d8b8d4b5388b6e1e87a0d1fb2766d
https://escholarship.org/uc/item/5h11w164

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Surgical treatment for cryptoglandular and Crohn's perianal fistulas: Protocol of an umbrella review

Autor: Li Yue, Peixin Du, Xuejun Yang, Chenyang Fang, Maojun Ge, Haikun Zhou, Qingming Wang, Zubing Mei, Yazhou He, Qin Feng, Bin Li, Zhuo Shao, Jinghua Gu

Publikováno v: PLoS ONE, Vol 16, Iss 5, p e0251460 (2021)
Mei, Z, Feng, Q, Du, P, Fang, C, Gu, J, Li, Y, Zhou, H, Shao, Z, Ge, M, He, Y, Yang, X & Wang, Q 2021, ' Surgical treatment for cryptoglandular and Crohn's perianal fistulas : Protocol of an umbrella review ', PLoS ONE, vol. 16, no. 5, pp. e0251460 . https://doi.org/10.1371/journal.pone.0251460
PLoS ONE

Introduction A high prevalence of cryptoglandular and Crohn’s perianal fistulas has been reported worldwide, and several surgical options are available for the management of anal fistula, with varying clinical efficacy. However, currently, the avai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c06edcc83a748bd8c2b83a202b35d8
https://doaj.org/article/206348bf4b434a63975897f35aa9ed78

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Prevalence and associated factors of hemorrhoids among adult patients visiting the surgical outpatient department in the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia

Autor: Mohammed Oumer, Anteneh Ayelign Kibret, Abebe Muche Moges

Publikováno v: PLoS ONE, Vol 16, Iss 4, p e0249736 (2021)
PLoS ONE

Introduction Hemorrhoidal disease is a very common benign anorectal disease. It affects millions of people around the world, and represent a major medical and socioeconomic problem. However, studies that determine the magnitude and risk factors are l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76dc9f67a10ac1f47abc9d4ec926ba0b
https://doaj.org/article/26b4106249d44074b1bce53fbd78755a

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Genome-wide host methylation profiling of anal and cervical carcinoma

Autor: Erin M. Siegel, Abidemi Ajidahun, Anders Berglund, Whitney Guerrero, Steven Eschrich, Ryan M. Putney, Anthony Magliocco, Bridget Riggs, Kathryn Winter, Jeff P. Simko, Jaffer A. Ajani, Chandan Guha, Gordon S. Okawara, Ibrahim Abdalla, Mark J. Becker, Joseph F. Pizzolato, Christopher H. Crane, Kevin D. Brown, David Shibata

Publikováno v: PLoS ONE, Vol 16, Iss 12 (2021)
PLoS ONE, Vol 16, Iss 12, p e0260857 (2021)
PLoS ONE

HPV infection results in changes in host gene methylation which, in turn, are thought to contribute to the neoplastic progression of HPV-associated cancers. The objective of this study was to identify joint and disease-specific genome-wide methylatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c219512ff31b13deb67d674906b65e
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659695/?tool=EBI

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Translation, validation and psychometric evaluation of the Persian (Farsi) version of the Low Anterior Resection Syndrome Score (LARS-P)

Autor: Mohammad Sadegh Fazeli, Ali Abbaszadeh-Kasbi, Behnam Behboudi, Alireza Kazemeini, Mohammad Reza Keramati, Seyed Mohsen Ahmadi-Tafti, Amir Keshvari

Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0247054 (2021)

Introduction Low anterior resection (LAR) for rectal cancer affects bowel function after the operation, causing a group of symptoms known as LAR Syndrome (LARS). LARS score is a patient-reported questionnaire to assess bowel dysfunction after the LAR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf591effb6e0d89b419ada1a1a50811
https://pubmed.ncbi.nlm.nih.gov/33630867

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Institutional mortality rate and cause of death at health facilities in Ghana between 2014 and 2018

Autor: Adobea Yaa Owusu, Mawuli Kushitor, Anthony Ofosu, Atsu Ayi, Sandra Boatemaa Kushitor, John Koku Awoonor-Williams

Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0256515 (2021)

Background The epidemiological transition, touted as occurring in Ghana, requires research that tracks the changing patterns of diseases in order to capture the trend and improve healthcare delivery. This study examines national trends in mortality r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0eea6c54fb9a2e78eee1d7080cf52e
https://pubmed.ncbi.nlm.nih.gov/34496000

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Human papillomavirus 16 L1 gene methylation as a potential biomarker for predicting anal intraepithelial neoplasia in men who have sex with men (MSM)

Autor: Tippawan Pankam, Parvapan Bhattarakosol, Arkom Chaiwongkot, Nittaya Phanuphak

Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0256852 (2021)

The human papillomavirus (HPV) 16 early promoter and L1 gene methylation were quantitatively measured using pyrosequencing assay in anal cells collected from men who have sex with men (MSM) to determine potential biomarkers for HPV-related anal cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f8865c2d4ba554712b09c4cf3ed552
https://doi.org/10.1371/journal.pone.0256852

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Improving five-year survival prediction via multitask learning across HPV-related cancers

Autor: David P. Widemann, André R. Gonçalves, Jan F. Nygård, Braden Soper, Ana Paula Sales, Mari Nygård, Priyadip Ray

Publikováno v: PLoS ONE
PLoS ONE, Vol 15, Iss 11, p e0241225 (2020)

Oncology is a highly siloed field of research in which sub-disciplinary specialization has limited the amount of information shared between researchers of distinct cancer types. This can be attributed to legitimate differences in the physiology and c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f21ded863d04519ea3b9bf504d75195
https://doi.org/10.1371/journal.pone.0241225

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