Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Anak A. S. S. K. Dharmapatni"'
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
The field of osteoimmunology has emerged in response to the range of evidences demonstrating the close interrelationship between the immune system and bone metabolism. This is pertinent to immune-mediated diseases, such as rheumatoid arthritis and pe
Externí odkaz:
https://doaj.org/article/f564784089f44760bd22bc23643ced7d
Autor:
Anak A. S. S. K. Dharmapatni, Melissa D. Cantley, Victor Marino, Egon Perilli, Tania N. Crotti, Malcolm D. Smith, David R. Haynes
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Objective. To investigate the effect of Embelin, an inhibitor of X-Linked Inhibitor of Apoptosis Protein (XIAP), on inflammation and bone erosion in a collagen antibody induced arthritis (CAIA) in mice. Methods. Four groups of mice (n=6 per group) we
Externí odkaz:
https://doaj.org/article/433908350b2a4c16926ee806317f55ec
Publikováno v:
Inflammation Research. 67:219-231
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that results in both local and systemic bone erosion, causing significant joint deformities and functional disability. The increased number of synovial fibroblasts, inflammatory c
Autor:
Kent Algate, Anak A S S K Dharmapatni, David R. Haynes, Gerald J. Atkins, Melissa Cantley, S. Saad, Tania N. Crotti, David M. Findlay
Publikováno v:
Acta Biomaterialia. 30:311-318
Peri-prosthetic osteolysis (PPO) occurs in response to prosthetic wear particles causing an inflammatory reaction in the surrounding tissue that leads to subsequent bone loss. Semaphorin-3a (SEM3A), neuropilin-1 (NRP1) and plexin-A1 (PLEXA1) are axon
Autor:
Tania N. Crotti, Jiake Xu, Anak A S S K Dharmapatni, David R. Haynes, Muhamad Syahrul Fitri Zawawi, Melissa Cantley, Egon Perilli, Victor Marino, P. Edward Purdue
Publikováno v:
Journal of Biomedical Materials Research Part A. 103:3572-3579
The study aimed to determine the effects of parthenolide (PAR) on bone volume (BV) and bone surface resorption as assessed by live-animal microcomputed tomography (μCT) and possible osteocyte death as indicated by empty lacunae histologically in pol
Publikováno v:
Journal of Immunology Research
Journal of Immunology Research, Vol 2015 (2015)
Journal of Immunology Research, Vol 2015 (2015)
The field of osteoimmunology has emerged in response to the range of evidences demonstrating the close interrelationship between the immune system and bone metabolism. This is pertinent to immune-mediated diseases, such as rheumatoid arthritis and pe
Autor:
Egon Perilli, Eleni Tsangari, Melissa Cantley, Tania N. Crotti, Romany L. Stansborough, Victor Marino, Rachel J. Gibson, Bonnie Williams, Anak A S S K Dharmapatni
Objective: To investigate the effect of caffeic acid phenethyl ester (CAPE) on local and systemic inflammation and bone loss in collagen antibody-induced arthritis (CAIA) mice. Methods: Four groups of mice (n = 8 per group) were allocated; control, C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cb522cd430f15c226ee0f9326b10cc
https://hdl.handle.net/11541.2/124511
https://hdl.handle.net/11541.2/124511
Autor:
Tania N. Crotti, David M. Findlay, A. C. Holding, Donald W. Howie, David R. Haynes, Anak A S S K Dharmapatni, Gerald J. Atkins, Ekram Alias
Publikováno v:
Acta Biomaterialia. 8:3104-3112
Wear particle-induced orthopaedic prosthesis loosening is associated with elevated osteoclast activity. The immunoreceptor tyrosine-based activation motif (ITAM)-related molecules OSCAR, FcRγ, TREM2 and DAP12 are important for osteoclast formation.
Publikováno v:
Rheumatology International. 32:535-540
The objective of the study was to determine whether cartilage expression of the bone regulating molecules receptor activator of nuclear factor κB ligand (RANKL) and osteoprotegerin (OPG) varies between the different grades of osteoarthritis (OA). Ca
Autor:
P. M. Bartold, Melissa Cantley, Anak A S S K Dharmapatni, Tania N. Crotti, Kent Algate, David R. Haynes
Publikováno v:
Journal of periodontal research. 51(2)
Background and Objective Histone deacetylase inhibitors (HDACi) are being considered to treat chronic inflammatory diseases at low doses. Currently HDACi that are more specific are being developed to target particular HDACs; therefore, this study aim